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Louisa Gross Horwitz Prize Lectures

The Louisa Gross Horwitz Prize was established under the will of the late S. Gross Horwitz through a bequest to Columbia University, and is named to honor the donor's mother. Louisa Gross Horwitz was the daughter of Dr. Samuel David Gross (1805-1889), a prominent surgeon of Philadelphia, and author of the outstanding Systems of Surgery, who served as President of the American Medical Association.  Each year, since its inception in 1967, the Louisa Gross Horwitz Prize has been awarded by Columbia University for outstanding basic research in the fields of biology or biochemistry. The purpose of this award is to honor a scientific investigator, or group of investigators, whose contributions to knowledge in either of these fields are deemed worthy of special recognition.

The Louisa Gross Horwitz Prize website

2017 Louisa Gross Horwitz Press Release



The 2017 Louisa Gross Horwitz Prize Lectures

Jeffrey I Gordon, MD

Jeffrey I Gordon, MD
Dr. Robert J Glaser Distinguished University Professor
Director, Edison Family Center for Genome Sciences and Systems Biology
Washington University School of Medicine

Lecture 1:
"The Gut Microbiota and Childhood Undernutrition: Looking at Human Developmental Biology from a Microbial Perspective"
Thursday, January 25, 2017
10:00 a.m.
Davis Auditorium (Rm. 412), Schapiro Center (CEPSR)
530 West 120th Street

Lecture 2:
"The Development of Microbiota-Directed Foods"
Thursday, January 25, 2017
3:30 p.m.
P&S Alumni Auditorium
650 West 168th Street, first floor

Jeffrey Gordon received his A.B. from Oberlin College and his M.D. from the University of Chicago. He completed his clinical training in internal medicine and gastroenterology at Barnes Hospital and Washington University and was a post-doctoral fellow in the Laboratory of Biochemistry at NIH's National Cancer Institute. In 1981, he joined the faculty of Washington University, where he has spent his entire career, first as a member of the Departments of Medicine and Biological Chemistry, then as Head of the Department of Molecular Biology and Pharmacology, and since 2003 as founding Director of the University's interdepartmental, interdisciplinary Center for Genome Sciences and Systems Biology. Dr. Gordon has had the privilege and pleasure of serving as research mentor to 127 PhD and MD/PhD students and post-doctoral fellows since he established his lab.

He is a member of the National Academy of Sciences, the American Academy of Arts and Sciences, the National Academy of Medicine, and the American Philosophical Society. His honors include the Selman A. Waksman Award in Microbiology from the National Academy of Sciences, the Robert Koch Award, the Passano Laureate Award, the Dickson Prize in Medicine, the King Faisal International Prize in Medicine, the Keio Medical Science Prize, the Steven C. Beering Award, and the Massry Prize.

Dr. Gordon's lab has used interdisciplinary approaches to characterize the assembly, operations, expressed properties, and biological effects of human gut microbial communities. The lab has done so by combining studies of twins as well as members of birth cohorts living in low- and high-income countries with studies of gnotobiotic animal models colonized with gut microbes from these individuals and fed components of their diets. His lab's results have emphasized how microbes function in a community context to impact health and disease. His discoveries of how diet and the gut microbiome interact have altered our understanding of two global health problems: obesity and childhood malnutrition. His group's work has provided a road map for establishing preclinical proof for a causal relationship between human microbial community configurations and health status and for identifying ways to alter community functions, including development of health-promoting foods during this time of rapid population growth and challenges to sustainable agriculture. This work has ushered in a new era of microbiome-based therapeutics and preventive medicine.



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PAST LOUISA GROSS HORWITZ PRIZE WINNERS

2016 Howard Cedar, MD, PhD
Emeritus Professor, Molecular Biology
Edmond J. Safra Distinguished Professor
Faculty of Medicine
Hebrew University of Jerusalem
Gary Felsenfeld, PhD
NIH Distinguished Investigator
Aharon Razin, PhD
Emeritus Professor, Biochemistry
Dr. Jacob Grunbaum Chair of Medical Science
Faculty of Medicine
Hebrew University of Jerusalem
2015 Lawrence Zipursky, PhD
Howard Hughes Medical Institute
University of California, Los Angeles
2014 James P. Allison, PhD
University of Texas
MD Anderson Cancer Center
2013 John Michael O'Keffe, PhD
University College London
Edvard I. Moser II, PhD
Norwegian University of Science and Technology
May-Britt Moser, PhD
Norwegian University of Science and Technology
2012 Joe Lutkenhaus, PhD
University of Kansas Medical School
Richard Losick, PhD
Harvard University
Lucy Shapiro, PhD
Stanford University School of Medicine
2011 Jeffery C. Hall, Ph.D.
Brandeis University
Michael Rosbash, Ph.D.
Brandeis University
Michael W. Young, Ph.D.
The Rockefeller University
2010 Thomas J. Kelly, M.D., Ph.D.
Memorial Sloan-Kettering Cancer Center
Bruce Stillman, Ph.D.
President, Cold Spring Harbor Laboratory
2009 Victor R. Ambrose, Ph.D.
University of Massachusetts Medical School
Gary Ruvkun, Ph.D. Harvard Medical School
2008 F. Ulrich Hartl, M.D., Max-Planck-Institute of Biochemistry Martinsried, Germany
Arthur Horwich, M.D., Yale University School of Medicine
2007 Joseph G. Gall, Carnegie Institution
Elizabeth H. Blackburn, University of California, San Francisco
Carol W. Greider, The Johns Hopkins University School of Medicine
2006 Roger D. Kornberg, Stanford School of Medicine
2005 Ada Yonath, Helen and Milton A. Kimmelman Center for Biomolecular Structure and Assembly of the Weizmann Institute of Science
2004 Tony Hunter, Salk Institute for Biological Studies
Anthony Pawson, University of Toronto
2003 Roderick MacKinnon, Rockefeller University
2002 James E. Rothman, Sloan-Kettering Institute
Randy W. Schekman, University of California, Berkeley
2001 Avram Hershko, Technion-Israel Institute of Technology, Israel
Alexander Varshavsky, California Institute of Technology, CA
2000 H. Robert Horvitz, Massachusetts Institute of Technology, Cambridge, MA
Stanley J. Korsmeyer, Harvard Medical School, Boston, MA
1999 Pierre Chambon, Institute Génétique et de Biologie Moleculaire et Cellulaire,
Université L. Pasteur, Illkirch-Strasbourg, France; Collége de France, Paris
Robert Roeder, Rockefeller University, New York, NY
Robert Tijan, Howard Hughes Medical Institute;University of California at Berkeley
1998 Arnold J. Levine, Rockefeller University, New York, NY
Bert Vogelstein, Johns Hopkins University, Baltimore, MD
1997 Stanley B. Prusiner, University of California, San Francisco
1996 Clay M. Armstrong, University of Pennsylvania, Philadelphia, PA
Bertil Hille, University of Washington, Seattle, WA
1995 Leland H. Hartwell, University of Washington, Seattle, WA
1994 Philippa Marrack, University of Colorado Health Sciences Center
John W. Kappler, University of Colorado Health Sciences Center
1993 Nicole Le Douarin, Institut d'Embryologie Cellulaire et Moléculaire, Nogent-sur-Marne, France
Donald Metcalf, The Walter and Eliza Hall Institute of Medicine, Victoria, Australia
1992 Christiane Nüsslein-Volhard, Max-Planck-Institut für Entwicklungbiologie, Tübingen, Germany
Edward B. Lewis, California Institute of Technology, Pasadena, CA
1991 Richard Ernst, Laboratorium für Physikalische Chemie, Zurich, Switzerland
Kurt Wuthrich, Swiss Federal Institute of Technology, Institut für Molekularbiologie und Biophysik, Zurich, Switzerland
1990 Stephen Harrison, Howard Hudges Medical Institute, Harvard University, Cambridge, MA
Michael G. Rossmann, Purdue University, West Lafayette, IN
Don C. Wiley, Howard Hughes Medical Center, Harvard Univ., Cambridge, MA
1989 Alfred G. Gilman, The University of Texas Southwestern Medical Ctr., Dallas, TX
Edwin G. Krebs, Howard Hughes Medical Institute Research Laboratories, University of Washington, Seattle, WA
1988 Thomas R. Cech, University of Colorado, Boulder, CO
Philip A. Sharp, Massachusetts Institute of Technology, Cambridge, MA
1987 Günter Blobel, The Rockefeller University, New York, NY
1986 Erwin Neher, Max-Planck Institute for Biophysical Chemistry, Gottingen, Germany
Bert Sakmann, Max-Planck Institute for Biophysical Chemistry, Gottingen, Germany
1985 Donald D. Brown, Carnegie Institution of Washington, Baltimore, MD
Mark Ptashne, Harvard University, Cambridge, MA
1984 Michael S. Brown, University of Texas Health Sciences Center, Dallas, TX
Joseph Goldstein, The University of Texas Southwestern Medical Center, Dallas, TX
1983 Stanley Cohen, Vanderbilt University School of Medicine, Nashville, TN
Vitkor Hamburger, Washington University, St. Louis, MO
Rita Levi-Montalcini, Instituto di Biologia Cellulare, Rome, Italy
1982 Barbara McClintock, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
Susumu Tonegawa, Massachusetts Institute of Technology, Cambridge, MA
1981 Aaron Klug, Medical Research Council, Laboratory of Molecular Biology, Cambridge, England
1980 Cesar Milstein, Medical Research Council, Laboratory of Molecular Biology, Cambridge, England
1979 Walter Gilbert, Harvard University, Cambridge, MA
Frederick Sanger, Medical Research Council of Molecular Biology, Cambridge, England
1978 David Hubel, Harvard University School of Medicine, Boston, MA
Vernon Mountcastle, Johns Hopkins Univ. School of Medicine, Baltimore, MD
Torsten Wiesel, Rockefeller University, New York, NY
1977 Michael Heidelberger, New York University School of Medicine, New York, NY
Elvin A. Kabat, Columbia University, New York, NY
Henry G. Kunkel, Columbia University, New York, NY
1976 Seymour Benzer, California Institute of Technology, Pasadena, CA
Charles Yanofsky, Stanford University, Stanford, CA
1975 K. Sune D. Bergstrom, Nobel Foundation, Stockholm, Sweden
Bengt Samuelsson, Karolinska Institute, Stockholm, Sweden
1974 Boris Ephrussi, Paris, France
1973 Renato Dulbecco, The Salk Institute, San Diego, CA
Harry Eagle, Albert Einstein College of Medicine
Theodore T. Puck, University of Colorado Medical Ctr., Denver, CO
1972 Stephen W. Kuffler
1971 Hugh E. Huxley, Medical Research Council, Laboratory of Molecular Biology,
Cambridge, England
1970 Albert Claude
George E. Palade, Yale University School of Medicine, New Haven, CT
Keith R. Porter, University of Maryland-Baltimore County, Catonsville, MD
1969 Max Delbrück, California Institute of Technology, Pasadena, CA
Salvador E. Luria, Massachusetts Institute of Techn., Cambridge, MA
1968 H. Gobind Khorana, Massachusetts Institute of Technology, Cambridge, MA
Marshall Warren Nirenberg, National Heart, Lung & Blood Institute, Bethesda, MD
1967 Luis F. Leloir, Instituto de Investigaciones Bioquimicas, Buenos Aires, Argentina


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