Research Training

During the second research year, the fellow has access to a wide range of investigative problems and technologies in clinical investigation, cell and molecular biology, and immunology in ongoing programs throughout the Medical Center and School of Public health. The project and mentor are chosen with the advice of the most senior members of the Division during the first year, and the entire second year is devoted to acquiring the necessary technology and pursuing the project. The fellow is expected to present his or her investigation results at a national meeting and prepare a manuscript for publication. Areas of focus include Immunology/Inflammation; Lung Biology; Asthma; Immune Deficiency; Food Allergy; Transplantation; Pulmonary Fibrosis; Ezcema; Environmental Health Sciences; Autoimmunity; Urticaria.

Additional research experience is often needed both to qualify for faculty appointment and to bring interesting projects to fruition. When the quality of performance during the second year suggests special aptitude for development in this direction, we will offer further post-doctoral experience and resources while supervising the fellow's application for independent support.

Bench/Translational Research

Divisional bench researchers are actively engaged in cutting edge research in environmental epigenetics and asthma, interstitial lung disease, immunology, and allergic immune responses and lung development. Additionally, Columbia University offers a diverse and expansive resource for fellows interested in bench/translational research training program some examples include the Columbia Center for Translational Immunology, the Columbia Center for Children’s Environmental Health (CCCEH) , and the Irving Institute for Clinical and translational research.  Fellows pursuing a career in basic or translational research of lung biology are eligible for funding through an NIH-funded T-32 training grant.

Examples of basic science investigators and laboratories available to fellows:

  • Dr. Rachel Miller is the Co-director of CCCEH  (environmental epigenetics and asthma, allergy)
  • Dr. Jining Lu (microRNAs as critical posttranscriptional regulators in airway epithelial or lung mesenchymal cell differentiation in response to injury)
  • Dr. Christian Schindler (Role of the JAK-STAT pathway in cytokine signal transduction)
  • Dr. Hans Snoeck (stem cell biology, lung development from human pluripotent stem cells with a focus on modeling of idiopathic pulmonary fibrosis)
  • Dr. Wellington Cardoso (mechanisms that regulate lung progenitor cell fate during lung development)

Clinical Research

The investigators in our division and our collaborators areas of clinical investigation include epidemiology, clinical trials, outcomes research, public health and health disparities. In addition, Columbia University offers a diverse and expansive resource for fellows interested in a clinical investigation training program. Columbia University Mailman School of Public Health is recognized as a leader in public health policy, education, research and environmental health sciences. Several members of our division have co-appointments in the Department of Environmental Health Sciences at Mailman School of Public Health with a particular interest in environmental health. We have collaborations with researchers investigating health effects of indoor air pollution exposure from biomass fuels in developing countries and the Pediatric Pulmonary Division.

The Mailman School offers Master of Science (MS) degrees in Biostatistics and Epidemiology. The Master of Science in Biostatistics has a Patient Oriented Research (POR) track for which there are 4-6 highly competitive full-tuition scholarships a year. Fellows in our Division have successfully competed for scholarships in years past. This is a two-year, 30 credit Master’s degree program supported through the NIH-funded Clinical and Translational Science Award program at Columbia. The goal of POR program is to prepare trainees to compete successfully for peer-reviewed research funding in clinical investigation. Trainees are required to complete a Master’s essay in the form of an NIH-style grant application that is written under the direct-supervision of a program faculty member.

Examples of Clinical Investigators:

  • Dr. Emily DiMango (clinical trials and epidemiology in Cystic Fibrosis and Asthma)
  • Dr. Irene Louh (critical care quality improvement)
  • Dr. Darby Jack (epidemiology, effects of biomass fuel on health in developing countries)
  • Dr. Rachel Miller (air pollution exposure and asthma, chemical exposure and asthma; Children's Respiratory Research and Environment Workgroup (CREW)
  • Dr. Yesim Demirdag (Primary immune deficiency)
  • Dr. Joyce Yu (Food Allergy)
  • Dr. Charles Emala (Airway remodeling)
  • Dr. Mathew Perzanowski (Fungal exposure and allergic disease; noninvasive methods for measuring airway inflammation)
  • Dr. Alexis Boneparth (Juvenile idiopathic arthritis)
  • Dr. Graham Barr (Epidemiology of COPD/emphysema, endothelial dysfunction and chronic lower respiratory disease)
  • Dr. Meyer Kattan (Inner City Asthma Consortium)