Academic Appointments
- Professor of Neuropsychology (in Neurology, the Taub Institute for Research on Alzheimer's Disease and the Aging Brain and the Gertrude H. Sergievsky Center)
Dr. Brickman uses advanced neuroimaging techniques to understand cognitive aging and dementia. He is particularly interested in white matter abnormalities and the intersection between vascular disease and Alzheimer's disease.
Ongoing Research: The effect of age on neuromorphology and its cognitive consequences. His current research efforts focus primarily on "normal" cognitive and structural changes across the adult lifespan. Specifically, he uses structural magnetic resonance imaging (MRI) to try to identify specific areas in the brain or coordinated patterns of brain tissue that are most vulnerable to the effects of age. Although age-associated decline across several neurocognitive domains has been well-documented, how age-associated differences in the brain's structure impacts cognitive abilities is still poorly understood. He is addressing this issue with a focus on individual differences in cognitive aging and on potential moderators and mediators of the relationships among age, neuromorphology, and cognition. He is particularly interested in understanding how cognitive reserve and cerebrovascular risk factors interact with the aging brain and cognitive abilities. For MRI quantification, these studies use traditional manual-tracing region-of-interest (ROI) approaches, ROI templates, white matter hyperintensity quantification protocols, voxel based morphometry, and novel multivariate/covariance analytic techniques. He also has an interest in using structural and functional neuroimaging techniques, traditional neuropsychological approaches, and functional assessment to understand neuro/psychiatric disorders, such as schizophrenia and dementia.
Departmental Appointments
- Department of Neurology
Division of Cognitive Neuroscience
Education and Training
- Graduate School of the City University of New York
- Fellowship: NewYork-Presbyterian Hospital/Columbia University Medical Center
Centers / Institutes / Programs
- Gertrude H. Sergievsky Center
- Taub Institute for Research on Alzheimer's Disease and the Aging Brain
Links
NIH Grants
BLOOD PRESSURE AND ADRD IN AFRICAN AMERICANS: THE JACKSON HEART STUDY (Federal Gov)
Sep 15 2019 - May 31 2024
USING RDOC NEGATIVE AND POSITIVE VALENCE PARADIGMS TO INVESTIGATE THE MECHANISMS OF NEUROPSYCHIATRIC SYMPTOMS (NPS) IN ALZHEIMER S DISEASE AND RELATED DEMENTIAS (Federal Gov)
Aug 1 2019 - May 31 2024
METFORMIN IN ALZHEIMER S DEMENTIA PREVENTION (MAP) (Federal Gov)
Aug 15 2019 - Apr 30 2024
RECONFIG - RECOVERY OF CONCIOUSNESS FOLLOWING INTRACEREBRAL HEMORRHAGE (Federal Gov)
Jun 15 2019 - Mar 31 2024
THE ROLE OF INFLAMMATION IN THE ASSOCIATION BETWEEN DIET AND ALZHEIMER S DISEASE (Federal Gov)
Mar 1 2019 - Nov 30 2023
TAU PET IMAGING IN RACIALLY/ETHNICALLY DIVERSE MIDDLE AGED ADULTS (Federal Gov)
Sep 1 2018 - Jun 30 2023
COLUMBIA CENTER FOR INTERDISCIPLINARY RESEARCH ON ALZHEIMER S DISEASE DISPARITIES (CIRAD) (Federal Gov)
Sep 1 2018 - Jun 30 2023
GENETIC CONTRIBUTION TO BRAIN ARTERIAL DILATATION AND ITS ROLE IN COGNITION AND DEMENTIA (Federal Gov)
May 1 2018 - Jun 30 2023
COGNITIVE FUNCTION, ALZHEIMER S DISEASE AND RELATED DISORDERS IN THE HAALSI COHORT (Federal Gov)
Sep 30 2018 - May 31 2023
NEUROANATOMICAL ASSOCIATIONS WITH THE FACTOR STRUCTURE UNDERLYING NEUROPSYCHIATRIC SYMPTOMS IN ALZHEIMER S DISEASE (Federal Gov)
Sep 30 2018 - May 31 2023
DIETARY MODULATION OF NEUROINFLAMMATION IN AGE-RELATED MEMORY DISORDERS (Federal Gov)
Sep 1 2018 - May 31 2023
OLFACTORY IMPAIRMENT IN OFFSPRING STUDY OF RACIAL DISPARITIES IN ALZHEIMERS DISEASE (Federal Gov)
Sep 1 2018 - May 31 2023
SUMMER OF TRANSLATIONAL AGING RESEARCH FOR UNDERGRADUATES (STARU) (Federal Gov)
Aug 1 2018 - Apr 30 2023
FUNCTIONAL CONNECTIVITY NETWORK IN DEFAULT MODE REGIONS PROVIDES THE UNDERLYING INFRASTRUCTURE FOR TASK-BASED FUNCTIONAL CO-DE/ACTIVATION NETWORKS (Federal Gov)
Jun 1 2018 - Apr 30 2023
ARE THERE ETHNIC DIFFERENCES IN BRAIN AMYLOID AND TAU IN THE SEVENTH DECADE OF LIFE? (Federal Gov)
Aug 1 2017 - Apr 30 2023
2/5 NEUROCOGNITIVE AND NEUROIMAGING BIOMARKERS: PREDICTING PROGRESSION TOWARDS DEMENTIA IN PATIENTS WITH TREATMENT RESISTANT LATE-LIFE DEPRESSION. (Federal Gov)
Sep 18 2017 - Jul 31 2022
COGNITIVE ANS NEURAL MECHANISMS OF THE ACCELERATED AGING PHENOTYPE IN PTSD (Federal Gov)
Sep 1 2017 - Jul 31 2022
RESILIENCE MECHANISMS UNDERLYING RACIAL/ETHNIC DISPARITIES IN ALZHEIMER S DISEASE (Federal Gov)
Aug 1 2017 - May 31 2022
AUDITORY, OLFACTORY, AND MOTOR CORRELATES OF IN-VIVO AD NEUROPATHOLOGY AND COGNITIVE DECLINE IN LATE-MIDDLE AGE (Federal Gov)
Jul 15 2019 - Jun 30 2021
WHICAP -GENETIC EPIDEMIOLOGY OF CEREBROVASCULAR FACTORS IN ALZHEIMER S DISEASE (Federal Gov)
Aug 1 2016 - Jun 30 2021
EFFECT OF LONG-TERM SLEEP RESTRICTION ON ENERGY BALANCE (Federal Gov)
Aug 17 2016 - May 31 2021
DIABETES STATUS AND BRAIN AMYLOID IN MIDDLE AGED HISPANICS (Federal Gov)
Sep 1 2015 - May 31 2021
VIDEO INFORMATION PROVIDER FOR HIV-ASSOCIATED NON-AIDS (VIP-HANA) SYMPTOMS (Federal Gov)
Jul 16 2015 - May 31 2021
ALZHEIMER S DISEASE RESEARCH CENTER - OVERALL (Federal Gov)
Jun 15 2015 - May 31 2021
BIOMARKERS OF ALZHEIMER S DISEASE IN ADULTS WITH DOWN SYNDROME (Federal Gov)
Sep 30 2015 - Apr 30 2021
OFFSPRING STUDY OF MECHANISMS OF RACIAL DISPARITIES IN ALZHEIMER S DISEASE (Federal Gov)
Sep 1 2016 - Mar 31 2021
INTERDISCIPLINARY RESEARCH TO UNDERSTAND THE INTERPLAY OF DIABETES, CEREBROVASCULAR DISEASE AND ALZHEIMER S DISEASE (Federal Gov)
Sep 30 2015 - Aug 31 2020
COOK FOR YOUR LIFE: MAINTAINING DIETARY CHANGE AMONG BREAST CANCER SURVIVORS (Federal Gov)
Apr 15 2015 - Jun 30 2020
WHITE MATTER HYPERINTENSITIES IN AGING AND DEMENTIA (Federal Gov)
Sep 30 2016 - Aug 31 2019
EXAMINATION OF THE EARLIEST SYMPTOMS AND BIOMARKERS OF FTLD MAPT CARRIERS (Federal Gov)
Sep 21 2012 - Jul 31 2019
ALEX HOUCK HHMI AWARD (Private)
Jul 2 2018 - Jun 29 2019
NOVEL COGNITIVE AND FUNCTIONAL MEASURES FOR ALZHEIMER S DISEASE PREVENTION TRIALS (Federal Gov)
Sep 1 2018 - May 31 2019
PSYCHOSOCIAL PROTECTIVE FACTORS IN COGNITIVE AND BRAIN AGING (Federal Gov)
Sep 30 2016 - Mar 30 2019
GENE-ENVIRONMENT INTERACTION IN COGNITION IN VENEZUELAN FAMILIES (Federal Gov)
Aug 1 2011 - Apr 30 2018
MRI, GENETIC AND COGNITIVE PRECURSORS OF AD AND DEMENTIA (Federal Gov)
Sep 15 2012 - Aug 31 2017
MRI, GENETIC AND COGNITIVE PRECURSORS OF AD AND DEMENTIA (Federal Gov)
Sep 15 2012 - May 31 2017
EXERCISE, AGE-RELATED MEMORY DECLINE, AND HIPPOCAMPAL FUNCTION (Federal Gov)
Sep 15 2010 - May 31 2017
EPIDEMIOLOGY OF BIOMARKERS OF RISK AND PROGRESSION IN LOAD (Federal Gov)
May 1 2010 - Apr 30 2017
RE-VISITING METHODS FOR MCI DIAGNOSIS TO IMPROVE BIOMARKER AND TRIAL FINDINGS (Federal Gov)
Mar 15 2016 - Feb 28 2017
MECHANISMS OF ANTIDEPRESSANT NONRESPONSE IN LATE LIFE DEPRESSION (Federal Gov)
Jan 1 2015 - Dec 31 2016
PSYCHOSOCIAL PROTECTIVE FACTORS IN COGNITIVE AND BRAIN AGING (Federal Gov)
Sep 30 2016 - Dec 29 2016
INTEGRATING NEUROIMAGING WITH STUDIES OF COGNITIVE AGING IN THE DOMINICAN REPUBLIC (Federal Gov)
Sep 30 2012 - Aug 31 2016
HIPPOCOMPAL AND COGNITIVE FUNCTION, EXERCISE, AND OVARIAN CANCER: A PILOT STUDY (Federal Gov)
Aug 1 2014 - Jul 31 2016
NEUROPATHOGENESIS OF CLADE C HIV IN SOUTH AFRICA (Federal Gov)
Jul 1 2015 - Dec 31 2015
NEUROIMAGING-GUIDED HISTOPATHOLOGICAL EXAMINAION OF WHITE MA TTER ABNORMALITIES IN AGING AND DEMENTIA (Private)
Jun 1 2012 - May 31 2014
UNDERSTANDING THE POTENTIAL ROLE OF CF WITH REGARD TO BRAIN FUNCTION AND COGNITION (Private)
Apr 16 2009 - May 15 2014
MEDITERRANEAN DIET AND OTHER DIETARY PATTERNS IN ALZHEIMER S DISEASE (Federal Gov)
Mar 1 2008 - Feb 28 2014
AN EX-VIVO STUDY OF WHITE MATTER HYPER INTENSITIES IN AGING AND ALZHEIMER S DISEASE (Private)
Oct 1 2010 - Sep 30 2013
ADULT NEUROGENESIS: BRIDGING THE GAP BETWEEIN MACRO AND MICRO-NEUROSCIENCES (Private)
Sep 14 2007 - Mar 14 2013
COGNITIVE BENEFITS OF CARDIAC REHABILITATION IN HEART FAILURE (Federal Gov)
Jun 1 2010 - Nov 30 2012
THE EFFECT OF AGE ON NEUROMORPHOLOGY AND ITS COGNITIVE (Federal Gov)
May 15 2007 - Apr 30 2012
EFFECT OF SLEEP DEPRIVATION ON FMRI-MEASURED COGNITIVE NETWO RKS (Federal Gov)
Mar 15 2002 - Oct 31 2010