Rachel L. Miller, M.D.

Professor of Medicine (In Pediatrics) and Environmental Health Sciences
Director, Division of Pediatric Allergy, Immunology and Rheumatology
Director, Allergy and Immunology Fellowship Program
Co-Deputy Director, CCCEH

Bio

Dr. Miller is board certified in Pulmonary Disease, Critical Care Medicine and Allergy and Immunology. She has appointments in 3 departments in 2 Columbia schools and is the Director of the Allergy and Immunology Fellowship program and Director of Adult Allergy. She was named as top pulmonologist in the 2011 and 2012 US News and World Report report and is a Fellow at the American Academy of Allergy Asthma and Immunology. Her clinical office specializes in the treatment of asthma and allergies at the John Edsall-John Wood Asthma Center.

In addition, Dr. Miller is the Co-Deputy Director of the Columbia Center for Childrens Environmental Health (CCCEH). Her research concentrates on the mechanisms for the onset of asthma. One large research focus involves establishing and studying a birth cohort from Northern Manhattan (www.CCCEH.org), determining the importance of environmental allergens, traffic-related pollutants, and phthalate and bisphenol A exposure to the onset of allergies, asthma, and Th2 immune responses. A major emphasis is on the role of prenatal and early postnatal exposure on later pediatric and adolescent asthma risk. Additional areas of research include identifying novel genetic by environment interactions important to the onset of asthma. She also has established several mouse models examining the importance of prenatal and postnatal environmental exposures on asthma risk. More recent initiatives have been to build a program in environmental epigenetics and asthma by studying DNA methylation in cell, mouse and human systems.

Education and Training

Undergraduate:
Harvard University: A.B., Magna Cum Laude, 1982-1986
Medical School:
New York University School of Medicine: M.D., 1986-1990
Internship:
NewYork-Prebyterian Hospital/Columbia University Medical Center, 1990-1993
Residency:
NewYork-Prebyterian Hospital/Columbia University Medical Center, 1990-1993
Fellowship(s):
Pulmonary and Critical Care Medicine, NewYork-Prebyterian Hospital/Columbia University Medical Center, 1993-1997;
Allergy and Immunology, NewYork-Prebyterian Hospital/Columbia University Medical Center, 1997-1999

Selected Honors and Awards

  • Harvard College Dean’s List
  • 1985 Collegiate National Rowing Championship, second place
  • 1986 Thomas T. Hoopes Prize for excellent senior honors thesis
  • 1986 Faculty Prize for distinguished senior honors thesis in psychobiology
  • 1987-1988 President of NYU Chapter of American Medical Student Association
  • 1990 Eve Flechner Award in Internal Medicine
  • 1999 Florence and Herbert Irving Clinical Research Career Award
  • 2007 AAAAI Clinical Fellowship Award to Allergy and Immunology Training Program at Columbia to support training of Dr. Kathleen Donohue
  • 2011-12 US News and World Report Top Doctor (pulmonologist)

 

Other Experience and Professional Membership

07/2001-Present
Director, Asthma Project, Columbia Center for Children;s Environmental Health
6/2005-Present
Fellow, American Academy of Allergy, Asthma and Immunology
06/2007-Present
Editorial Board of Clinical Medicine: Respiratory and Pulmonary Medicine
07/01/2007-Present
Director of Allergy, New York Presbyterian Hospital
07/01/2007-Present
Associate Director, Lead Physician Scientist, P50 Disease Investigation through Specialized Clinically-Oriented Ventures in Environment Research
01/2008-Present
Editorial Board of the Open Allergy Journal
01/01/2009-Present
Co-Deputy Director, Columbia Center for Children's Environmental Health
01/04/2011-Present
Co-Investigaror/Lab Supervisor for ICAC (Inner City Asthma Consortium) Ureca study
03/2012-Present
Editorial Board of the Journal of Allergy and Clinical Immunology, Impact factor 11.003

Clinical

For appointments: 

622 West 168th Street, 8 Center
New York, NY 10032

P: (212) 305-0631
F: (212) 305-2277

Specialties

  • Allergy & Immunology
  • Critical Care Medicine
  • Pulmonary Disease Medicine

Clinical Expertise

  • Asthma
  • Allergy
  • Anaphylaxis
  • Clinical Immunology

Clinical Centers

Board Certifications

  • Internal Medicine, Diplomate, 1993; 2002
  • Pulmonary Disease, Diplomate, 1996; 2005
  • Critical Care Medicine, Diplomate, 1997; 2006
  • Allergy and Immunology, Diplomate, 1999; 2009

Research

Contact Information: 

Columbia University
College of Physicians & Surgeons
Miller Laboratory
630 W. 168th Street
P&S 8-430
New York, NY, 10032

Academic Office
P: (212) 305-7759
F: (212) 305-2277

Laboratory
P: (212) 342-1671

Email: rlm14@columbia.edu

Research Interests

  • Environmental epigenetics and asthma, allergy
  • Air pollution exposure and asthma
  • Chemical (phthalates, pesticides, bisphenol A) exposure and asthma

Selected Funding

  • 2R01ES13163-6A1
  • 5P01ES09600/RD-83214101
  • RO1 ES020926
  • R21 AI101296
  • 1R01HL118612A1

Selected Publications (from total list of 106 publications)

  1. Rastogi, D., Chaodong Wang, Xia Mao, Cynthia Lendor, Paul B. Rothman, Rachel L. Miller. Antigen-specific immune responses to influenza vaccine in utero, Journal of Clinical Investigation, 117 (6):1637-46, 2007.
  2. Donohue, Kathleen M., Umaima Al-alem, Matthew S. Perzanowski, Ginger L. Chew, Alina Johnson, Adnan Divjan, Elizabeth A. Kelvin, Lori A. Hoepner, Frederica P. Perera, Rachel L. Miller. Anti-cockroach, mouse IgE is associated with early wheeze and atopy in an inner-city birth cohort, Journal of Allergy and Clinical Immunology, 122(5):914-20, 2008.
  3. Miller, Rachel L and Shuk-mei Ho Environmental epigenetics and asthma: Current concepts and call for studies, American Journal of Respiratory and Critical Care Medicine, 177:567-573, 2008.
  4. Miller, Rachel L. Prenatal maternal diet and asthma risk. The Journal of Clinical Investigation, 118(10):3265-3268, 2008.
  5. Patel, Molini M., Lori Hoepner, Robin Garfinkel, Steven Chillrud, Andria Reyes, Frederica Perera, Rachel L. Miller. Ambient metals and elemental carbon in fine particulate matter predict wheeze and cough in very young urban children, American Journal of Respiratory and Critical Care Medicine, 180 (11):1107-1113. 2009.
  6. Marilyn Reyes , Matthew S. Perzanowski, Robin M. Whyatt, Elizabeth A. Kelvin, Andrew G. Rundle, Diurka Diaz, Beatriz Plaza, Lori Hoepner, Frederica P. Perera, Virginia Rauh, Rachel L. Miller. Maternal demoralization is associated with childhood wheeze, but not IgE, at age five years in an inner-city cohort, Annals of Allergy, Asthma and Immunology, 107 (1): 42-49, 2011.
  7. Phillip Factor, Alexander Akhmedov, Jake MacDonald, Anna Xu, Jie Wu, Trisha Das, Raymond Panettieri, Frederica Perera, and Rachel L. Miller. Polycyclic aromatic hydrocarbons impair b2AR function in airway epithelial and smooth muscle cells, The American Journal of Respiratory Cell and Molecular Biology, 45: 1045-1049, 2011.
  8. Molini M. Patel, James W. Quinn, Kyung Hwa Jung, Lori Hoepner, Diurka Diaz, Matthew Perzanowski, Andrew Rundle, Patrick L. Kinney, Frederica P. Perera, and Rachel L. Miller. Traffic density and point sources of air pollution associated with asthma and allergy from birth to age 5 years among New York City children, Environmental Research, 111(8): 1222-29, 2011.
  9. Rachel L. Miller and Cara L. Agerstrand. Targeting indoor air pollution: Interpreting the RESPIRE trial, The Lancet, 378:1682-83, 2011.
  10. Allan C. Just, Robin M. Whyatt, Matthew S. Perzanowski, Antonia M. Calafat, Frederica P. Perera, Inge F. Goldstein, Qixuan Chen, Andrew G. Rundle, Rachel L. Miller. Prenatal exposure to butylbenzyl phthalate and early eczema in an urban cohort, Environmental Health Perspectives, 120 (10):1475-80, 2012.
  11. Matthew S. Perzanowski, Ginger L. Chew, Adnan Divjan, Kyung Hwa Jung, Robert Ridder, Deliang Tang, Diurka Diaz, Inge F. Goldstein, Patrick L. Kinney, Andrew G. Rundle, David E. Camann, Frederica P. Perera, Rachel L. Miller. Early-life cockroach allergen and polycyclic aromatic hydrocarbon exposures predict cockroach sensitization among inner-city children. J. Allergy and Clinical Immunology, 131(3):886-893, 2013
  12. Kyung Hwa Jung, Matthew Perzanowski, Andrew Rundle, Kathleen Moors, Beizhan Yan, Steven N. Chillrud, Robin Whyatt, David Camann, Frederica P. Perera, Rachel L. Miller. Polycyclic aromatic hydrocarbon exposure, obesity and childhood asthma in an urban cohort, Environmental Research, 128:35-41, 2014.
  13. Robin M. Whyatt, Matthew S. Perzanowski, Allan C. Just, Andrew G. Rundle, Kathleen M. Donohue, Antonia M. Calafat, Lori Hoepner, Frederica P. Perera, Rachel L. Miller. Prenatal exposure to phthalates and asthma development among inner-city children. Environmental Health Perspectives, provisionally accepted, 2014.

View Dr. Miller's full list of publications from PubMed