Keith Brenner, M.D.

Assistant Professor of Clinical Medicine

Bio

Dr. Brenner graduated from the Johns Hopkins School of Medicine and performed postgraduate training at Columbia University Medical Center, completing residency in internal medicine and fellowship in pulmonary and critical care medicine.

Dr. Brenner’s focus is on providing excellent care to patients with pulmonary disease in the office and hospital setting. His clinical interests include interventional bronchoscopy, lung cancer screening, COPD, asthma, and interstitial lung disease. He participates in research studies of COPD treatment, bronchoscopic lung volume reduction for emphysema, and novel applications of extracorporeal membrane oxygenation (ECMO) as a treatment for respiratory failure.

Education and Training

Undergraduate:
B.S.  Rutgers, the State University of New Jersey Rutgers College, New Brunswick, NJ, 1996-2000
Medical School:
Johns Hopkins University School of Medicine, Baltimore, MD, 2001-2005
Residency:
Internal Medicine, New York Presbyterian Hospital, Columbia University Medical Center, New York, NY, 2005-2008
Chief Residency:
Internal Medicine, New York Presbyterian Hospital, Columbia University Medical Center, New York, NY, 2008-2009
Fellowship(s):
Pulmonary and Critical Care Medicine, New York Presbyterian Hospital, Columbia University Medical Center, New York, NY,  2009-2012

Selected Honors and Awards

  • 2005 Alpha Omega Alpha
  • 2008 Arnold P. Gold Foundation, Humanism and Excellence in Teaching Award
  • 2008-2009 Chief Resident, Internal Medicine Residency New York Presbyterian Hospital, Columbia University Medical Center
  • 2011 American Thoracic Society Travel Award

 

Clinical

For appointments: 

Columbia Pulmonary Associates
Herbert Irving Pavilion
161 Fort Washington Avenue, 3rd Floor
New York, NY 10032

P: 212-305-7448
F: 212-305-0242

Specialties

  • Pulmonary Disease Medicine
  • Critical Care Medicine

Clinical Expertise

  • General pulmonary disease
  • COPD
  • Lung cancer screening and diagnosis
  • Interventional bronchoscopy
  • Interstitial lung disease
  • Bronchial thermoplasty for severe asthma

Clinical Centers

Board Certifications

  • Internal Medicine Diplomate, 2008
  • Pulmonary Disease Diplomate, 2011
  • Critical Care Medicine (Eligible 2012)

Research

Research Interests

  • Bronchoscopic lung volume for emphysema
  • COPD treatment after acute exacerbation
  • Long-term outcomes after ECMO for ARDS
  • Extracorporeal CO2 removal for COPD exacerbation

Selected Publications

  1. Brenner K, Cunningham J, Bacchetta M, Brodie D. Catheter Associated Deep Vein Thrombosis
    And Level Of Anticoagulation In Adult Patients Requiring Extracorporeal Membrane Oxygenation
    For Respiratory Failure. American Thoracic Society. May 2012. Abstract 27987.
  2. Brenner K, Baldwin MR, Agerstrand CL, Burkart KM, Bulman WA, Bacchetta MD, Brodie D.
    Improvements in dynamic pulmonary compliance with a very low tidal volume ventilation strategy
    and extracorporeal membrane oxygenation for severe acute respiratory distress syndrome. Am J
    Respir Crit Care Med 183; 2011:A1648.
  3. Baldwin MR, Bacchetta M, Brodie HD, Brenner K, Agerstrand C.L., Burkart K.M., Bulman W.A.,
    Veno-venous extra corporeal membrane oxygenation with bi-caval dual lumen internal jugular
    catheter permits safe transport of adult patients with severe acute respiratory distress syndrome.
    Am J Respir Crit Care Med 183; 2011:A1649.
  4. Agerstrand CA, Baldwin MR, Brodie HD Brenner K, Agerstrand C.L., Burkart K.M., Bulman W.A.
    Conservative blood transfusion strategies are effective for the management of adult patients with
    severe acute respiratory distress syndrome requiring extracorporeal membrane oxygenation.
    Am J Respir Crit Care Med 183; 2011:A1655.
  5. Brenner K, Yip C, Cole S. A 25 year old pregnant woman with a large lung mass. Am J Respir
    Crit Care Med 181; 2010:A6873.
  6. Keating CL, Wang S, Brenner K, Wang T, Powell C, Circulating Progenitor Cells in Non-Small Cell
    Lung Cancer Patients. American Thoracic Society. May 2008. Abstract 542.
  7. Zimmer M, Ebert BL, Neil C, Brenner K, Papaioannou I, Melas A, Tolliday N, Lamb J, Pantopoulos
    K, Golub T, Iliopoulos O. Small-molecule inhibitors of HIF-2a translation links its 5’UTR ironresponsive element to oxygen sensing. Molecular Cell. 2008. 32: 838-48.
  8. Abukhdeir AM, Vitolo MI, Argani P, De Marzo AM, Karakas B, Konishi H, Gustin JP, Lauring J,
    Garay JP, Pendleton C, Konishi Y, Blair BG, Brenner K, Garrett-Mayer E, Carraway H, Bachman
    KE, Park BH. Tamoxifen-stimulated growth of breast cancer due to p21 loss. Proceeding of the
    National Academy of Science. 2008. 105: 288-93.
  9. Huang Y, Keen JC, Pledgie A, Marton LJ, Zhu T, Sukumar S, Park BH, Blair B, Brenner K, Casero
    RA Jr, Davidson NE. Polyamine analogues down-regulate estrogen receptor alpha expression in
    human breast cancer cells. Journal of Biological Chemistry. 2006. 281:19055-63.
  10. Abukhdeir AM, Blair BG, Brenner K, Karakas B, Konishi H, Lim J, Sahasranaman V, Huang Y,
    Keen J, Davidson N, Vitolo MI, Bachman KE, Park BH. Physiologic estrogen receptor alpha
    signaling in non-tumorigenic human mammary epithelial cells. Breast Cancer Research and
    Treatment. 2005. 99:23-33.

*Please see CV for complete list of publications