Jeremy R. Beitler, M.D., MPH

Assistant Professor of Medicine
Director of Clinical Research, Center for Acute Respiratory Failure

Bio

Dr. Jeremy Beitler is a pulmonary intensivist and Director of Clinical Research for the Center for Acute Respiratory Failure at Columbia University. Clinically, he cares for patients admitted to the medical intensive care units (MICUs) at New York-Presbyterian Hospital / Columbia University Medical Center. His NIH-funded research program focuses on optimizing mechanical ventilatory support for patients with acute respiratory failure, including acute respiratory distress syndrome (ARDS).

ARDS occurs in up to one-quarter of all critically ill adults receiving mechanical ventilation. Despite considerable advances in understanding of disease pathogenesis, ARDS remains associated with high risk of death—up to 45% mortality for severe disease. The most effective proven therapy for ARDS is to limit the degree of lung stretch with each machine-supported breath. Yet, how best to personalize ventilatory support to each individual patient’s unique risk of lung injury is unclear. Dr. Beitler’s research seeks to address this gap by advancing understanding of the interaction between pulmonary biomechanics and lung biology. He uses esophageal manometry to quantify lung stress in real-time at bedside, paired with serial measures of lung injury biomarkers to identify the patient-specific dose-response between lung stretch and biological injury.

Dr. Beitler would like to express his gratitude to the many patients and families who have advanced this research by participating in clinical studies. He sincerely believes your essential support ultimately will help improve survival and decrease morbidity for patients suffering from acute respiratory failure.

Education and Training

Undergraduate:
B.S. in Biology and Psychology, B.A. in Philosophy, Honors in Bioengineering, Pennsylvania State University
Graduate:
M.P.H in Clinical Effectiveness, Harvard School of Public Health
Medical School:
New York University School of Medicine
Residency:
New York University and Tufts Medical Center
Fellowship:
Clinical and research fellow, Harvard Combined Program at Massachusetts General Hospital, Brigham & Women’s Hospital, Beth Israel Deaconess Medical Center

Selected Honors and Awards

2018
Carmel Research Excellence Prize, Western Region, American Federation for Medical Research
2018
Faculty Teaching Award, University of California San Diego Medicine Chief Resident Selection
2016
Faculty Teaching Award, University of California San Diego Medicine Residency
2013
Fellow Teaching Award, Brigham & Women’s Hospital Residency
2010
Postgraduate Research Award, New York University Department of Medicine
2008
Award for Outstanding Community Service, Medical Society of the State of New York

Other Experience and Professional Membership

  • Critical Care Program Committee, American Thoracic Society (2015-present)
  • Publications Committee, American Thoracic Society (2015-2016)
  • Pleural Pressure Working Group, European Society of Intensive Care Medicine (2017-present)
  • Section on Acute Respiratory Failure, European Society of Intensive Care Medicine (2017-present)

Clinical

Specialties

  • Critical care medicine
  • Pulmonary disease

Clinical Expertise

  • Acute respiratory failure
  • Acute respiratory distress syndrome (ARDS)
  • Mechanical ventilation and patient-ventilator dyssynchrony
  • Post-cardiac arrest care
  • Septic shock
  • Critical care medicine

Clinical Centers

  • Center for Acute Respiratory Failure

Board Certifications

  • Critical Care Medicine Diplomate
  • Pulmonary Disease Diplomate
  • Internal Medicine Diplomate

Research

Research Interests

  • Acute respiratory failure
  • Acute respiratory distress syndrome (ARDS)
  • Ventilation-induced lung and extrapulmonary organ injury
  • Patient-ventilator dyssynchrony
  • Esophageal manometry
  • Post-cardiac arrest syndrome (PCAS)

Funding

Ongoing Research Support

NIH K23-HL133489 (PI: Beitler)
Breath stacking dyssynchrony in acute respiratory distress syndrome

American Thoracic Society Unrestricted Grant in Critical Care (PI: Beitler)
Sizing the “baby lung” for lung injury risk in acute respiratory distress syndrome

NIH U01-HL123004 (PI: Matthay; Ancillary study PI: Beitler)
RED ROSE: Reconciling Expected vs. Delivered tidal volumes in the ROSE Trial

NIH Loan Repayment Program (PI: Beitler)
Breath stacking dyssynchrony in acute respiratory distress syndrome

Completed Research Support

NIH UM1-HL108724 (PI: Talmor; site PI: Beitler)
EPVent2: A phase II trial of esophageal pressure-guided ventilation in ARDS

NIH T32-HL007633 (PI: Choi; fellow: Beitler)
Integrative training in respiratory research

NIH R01-HL063348 (PI: Ratcliff; student research associate: Beitler)
Quantitative analysis of left ventriculoplasty

Select Publications

  1. Anderson RJ, Jinadasa SP, Hsu L, Ghafouri TB, Tyagi S, Joshua J, Mueller A, Talmor D, Sell RE, Beitler JR. Shock subtypes by left ventricular ejection fraction following out-of-hospital cardiac arrest. Critical Care. 2018;22:162.
  2. Beitler JR, Ghafouri TB, Jindasa SP, Mueller A, Hsu L, Anderson RJ, Joshua J, Tyagi S, Malhotra A, Sell RE, Talmor D. Favorable neurocognitive outcome with low tidal volume ventilation after cardiac arrest. American Journal of Respiratory and Critical Care Medicine. 2017;195:1198-1206.
  3. Hepokoski M, Englert JA, Baron RM, Crotty-Alexander LE, Fuster MM, Beitler JR, Malhotra A, Singh P. Ventilator-induced lung injury increases expression of inflammatory mediators in the kidney. American Journal of Physiology Renal Physiology. 2017;312:F654-660.
  4. Beitler JR, Owens RL, Malhotra A. Unmasking a role for noninvasive ventilation in early acute respiratory distress syndrome. JAMA. 2016;315:2401-2403.
  5. Beitler JR, Goligher EC, Schmidt M, Spieth PM, Zanella A, Martin-Loeches I, Calfee CS, Cavalcanti AB, ARDSne(x)t Investigators. Personalized medicine for ARDS: the 2035 research agenda. Intensive Care Medicine. 2016;42:756-767.
  6. Beitler JR, Sands SA, Loring SH, Owens RL, Malhotra A, Spragg RG, Matthay MA, Thompson BT, Talmor D. Quantifying unintended exposure to high tidal volumes from breath stacking dyssynchrony in ARDS: the BREATHE Criteria. Intensive Care Medicine. 2016;42:1427-1436.
  7. Beitler JR, Majumdar R, Hubmayr RD, Malhotra A, Thompson BT, Owens RL, Loring SH, Talmor D. Volume delivered during recruitment maneuver predicts lung stress in acute respiratory distress syndrome. Critical Care Medicine. 2016;44:91-99.
  8. Beitler JR, Guérin C, Ayzac L, Mancebo J, Bates DM, Malhotra A, Talmor D. PEEP titration during prone positioning for acute respiratory distress syndrome. Critical Care. 2015;19:436.
  9. Beitler JR, Schoenfeld DA, Thompson BT. Preventing ARDS: progress, promise, and pitfalls. Chest. 2014;146:1102-1113.
  10. Beitler JR, Shaefi S, Montesi SB, Devlin A, Loring SH, Talmor D, Malhotra A. Prone positioning reduces mortality from acute respiratory distress syndrome in the low tidal volume era: a meta-analysis. Intensive Care Medicine. 2014;40:332-341.

For a complete listing of publications by Dr. Beitler, see his PubMed Bibliography.