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Long-term Use of Osteoporosis Drugs Associated with Unusual Fractures

Most hip fractures due to osteoporosis follow the same pattern: a fall and the bone around the hip joint shatters into pieces. Two to three years ago, orthopedic surgeons began seeing an increase in unusual breaks that snapped the thighbone in two, often with no warning.

Such “atypical femur fractures” are associated with long-term use of a widely prescribed class of drugs for osteoporosis, as found by an expert panel led by Elizabeth Shane, M.D., professor of medicine at P&S.

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