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P&S Journal

P&S Journal: Winter 1995, Vol.15, No.1
P&S News
Center to Develop Medications for Substance Abuse

The National Institute of Mental Health has awarded $1.045 million to the Division on Substance Abuse at the New York State Psychiatric Institute to establish a center dedicated to the development of novel medications to treat cocaine and heroin abuse.
Headed by Dr. Herbert Kleber, P&S professor of psychiatry, and Dr. Marian Fischman, P&S professor of behavioral biology in psychiatry, the center is one of three new federally funded centers in the country (two existing centers received renewed funding). The center is based on the belief that because the addict population is heterogenous, effective medications that help subgroups are more likely than universal antidotes for the entire population.
With that philosophy in mind, three center projects have been funded for the first year of the five-year grant: a laboratory model for heroin abuse that could increase understanding of aspects of heroin use in human subjects and help develop new medications; brain imaging to measure cocaine effects that could serve as markers in medication development; and new approaches to medications for cocaine abuse.

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