Clinical Activities

Clinical Activities 

The Division of Pediatric Infectious Diseases provides subspecialty, consultative care to all children with a variety of infectious conditions seen at our hospital and affiliates. Clinical care includes laboratory evaluations, diagnosis, antimicrobial treatment, and management of children with bacterial, viral, fungal and parasite diseases. The Division frequently provides guidance in the management of infections in children with underlying conditions including:

  • Pulmonary infections - TB and TB exposure, complicated pneumonias
  • Heart disease – pre-operative consultation, prevention, and management of the complications of heart transplantation, congenital heart disease
  • GI disorders – management of infectious complications of IBD, short gut, central line infections
  • Orthopedics – management of bone infections, infectious complications of orthopedic devices
  • Transplant ID – The Division routinely evaluates patients pre-transplantation and follows them through their course of recovery

Our service provides 24/7 coverage for infectious disease issues in general pediatrics and affiliated subspecialties. The Division provides guidance on all positive blood cultures and assistance with antimicrobial stewardship activities as it relates to patient care and the prevention of antibiotic overuse.

The Division also works closely with the Department of Epidemiology to provide guidance for communicable infections and determination of isolation precautions as is needed. Peds ID also has a pediatric and adolescent HIV clinic with provides primary care and STD specific care to the pediatric and adolescent HIV patients.

Research

See the "Research" section on the Division of Pediatric Infectious Diseases for details on each investigator’s research program. Some of the topics being studied include the following:

Microbial Pathogenesis

  • A. Prince, MD, D. Parker, PhD - Molecular aspects of the pathogenesis of pneumonia and skin infection due to MRSA, K. pneumoniae, and P. aeruginosa. Role of T cells in the response to MRSA in the lung.
  • A. Moscona, MD, M. Porotto, PhD – Molecular basis for paromyxoviral entry into respiratory cells, engineering peptides to block entry of measles and henipaviruses, development of protease- resistant peptides as antivirals
  • A. Gershon, MD – Varicella-zoster virus infection of the enteric nervous system

Hospital Epidemiology

  • Lisa Saiman, MD, Philip Zachariah, MD – Infection control in Cystic Fibrosis, prevention of central line associated infections in the neonatal ICU, prevention of surgical site infection, use of the electronic medical record for epidemiological studies.
  • Philip Graham, MD – Hospital based infection prevention and control strategies

Clinical/Translational Research

  • Philip LaRussa, MD, A. Gershon MD - Safety of immunizations (CISA), efficacy and safety of varicella vaccine, Pediatric HIV prevention.
  • Natalie Neu, MD – Epidemiology of adolescent sexually transmitted disease and HIV, Infection control in pediatric long term care facilities
  • Marc Foca, MD – Infection prevention strategies in transplant patients, mitochondrial dysfunction and the pharmacology of antiretrovirals