Basic Research into Lymphoma

The primary focus of our laboratory program is to translate the latest scientific discoveries directly into new treatments for patients with lymphoma. This operation involves everything from early discovery and chemistry of new small molecules through preclinical drug development and biochemical pharmacology. Central to our laboratory focus on developing the most promising drugs as quickly as possible, is the reliance on the development of novel animal models of the disease. These unique models allow us to assess safety and efficacy very early in the development process, and to refine the optimal strategies for application in the clinic. Additionally, we believe that no drug being developed today will be used exclusively as a single agent; hence, we initiate the evaluation of drugs in combination in order to identify only the most promising and synergistic combination to move forward into the clinic. These techniques employ the use of high-throughput combinatorial screening.