Blood and Bone Marrow Transplantation

The Bone Marrow Transplantation (BMT) Service is under the leadership of Markus Y. Mapara, M.D., Ph.D., is dedicated to providing exceptional patient care and novel treatment options for patients with malignant and benign diseases of the blood-building system who require an autologous or allogeneic transplant. These conditions include:

Our protocols focus on enhancing outcome after allogeneic transplantation by reducing treatment-related complications and reducing disease recurrence after transplant. Laboratory and clinical research is focused on understanding the mechanisms underlying the biology of graft-versus-host disease and developing novel approaches for its prevention and treatment especially in patients undergoing mismatched transplants. Development of recurrent disease after transplant remains a major problem.

A particular interest of our program is aimed at providing stem cell transplantation for patients with lymphoid malignancies. In close collaboration with the Multiple Myeloma Service and the Lymphoma Center novel strategies are being developed to improve outcome of patients undergoing autologous and allogeneic BMT. Furthermore, in close collaboration with the Columbia Center for Translational Immunology directed by Megan Sykes, MD it is planned to develop protocols which allow combined transplantation of solid organs and bone marrow for induction of tolerance obviating the need for lifelong immunosuppression.



  • Clinical Coordinator   (212) 305-8619


New Patient Appointments
(212) 305-5098
NewYork-Presbyterian Operator
(212) 305-2500