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Taub in the News Archive
2015-2016 | 2011-2014
CUMCGoing Retro: Obscure Protein Complex Furnishes Fresh Clues for Alzheimer's Investigators
By Andrea Crawford
November 12, 2014
"Columbia neurologist Scott Small, MD, was hot on the trail of a relatively unknown cellular AD illocomponent known as retromer and sure he was on to something big…" [read more]
NEW YORK TIMESTo Improve a Memory, Consider Chocolate
By Pam Belluck
October 26, 2014
"Science edged closer on Sunday to showing that an antioxidant in chocolate appears to improve some memory skills that people lose with age…" [read more]
Also covered by: WASHINGTON POST, NEW YORK TIMES, TIME, NBC TODAY, ABC NEWS, CBS NEW YORK, SCIENTIFIC AMERICAN, IFL SCIENCE!, and THE GUARDIAN.
NEW YORK TIMESBreakthrough Replicates Human Brain Cells for Use in Alzheimer's Research
By Gina Kolata
"For the first time, and to the astonishment of many of their colleagues, researchers created what they call Alzheimer's in a Dish…" [read more]
Also covered by: BOSTON GLOBE
THE WASHINGTON POSTAlzheimer's researchers hunt for new tools to identify disease's onset
By Fredrick Kunkle
July 13, 2014
"A simple test of a person's ability to identify odors and noninvasive eye exams might someday help doctors learn whether their patients are at risk of Alzheimer's disease…" [read more]
Also covered by:
THE TELEGRAPH: Eye tests 'could spot' early Alzheimer's disease
NBC NEWS: Worried You May Be Developing Alzheimer's? Check Your Eyes
THE WALL STREET JOURNAL: Key to Detecting Alzheimer's Early Could Be in the Eye
MEDICAL DAILY: Alzheimer's Early Detection May Soon Be Possible With Smell, Eye Exams
RESEARCHERS RECEIVE $12.6M NIH GRANT TO STUDY ALZHEIMER'S GENETICS"Researchers from Columbia University's Taub Institute for Research on Alzheimer's Disease and the Aging Brain and Departments of Neurology, Epidemiology, and Systems Biology are part of a five-university collaboration receiving a $12.6 million, four-year grant from the National Institute on Aging (NIA), part of the National Institutes of Health (NIH), to identify rare genetic variants that may either protect against or contribute to Alzheimer's disease risk." [read more]
SCIENCEPotential Alzheimer's Drug Spurs Protein Recycling
By Ken Garber
April 25, 2014
"Small's discovery that retromers are lacking in the precise area of the brain first affected by Alzheimer's disease offered a possible solution to one of the condition's biggest puzzles…" [read more]
Also covered by:
CUMC NEWSROOM: "Chaperone" Compounds Offer New Approach to Alzheimer's Treatment
COLUMBIA UNIVERSITY MEDICAL CENTERAging and the Changing Landscape of Memory
April 9, 2014
"We now know that the dentate gyrus is important for a particular kind of memory called pattern separation, which allows us to distinguish things that are similar, like faces, but also clearly distinct," says Dr. Small [read more]
COLUMBIA UNIVERSITY MEDICAL CENTEREver-So-Slight Delay Improves Decision-Making Accuracy
March 7, 2014
"Columbia University Medical Center (CUMC) researchers have found that decision-making accuracy can be improved by postponing…" [read more]
TODAY'S DIETITONThe Mediterranean Diet and Cognition
By Lindsey Getz
February 4, 2014
"Growing evidence suggests that following this eating pattern may improve memory and prevent neurodegenerative disease…" [read more]
HUFFINGTON POSTIs It Alzheimer's?
By Richard W. Besdine, M.D.
January 9, 2013
"…neurologist Scott Small, M.D., Ph.D., a Beeson scholar and recipient of a Hartford/AFAR Collaborative Research Award, published direct scientific evidence of the neurological difference between memory loss and Alzheimer's." [read more]
COLUMBIA UNIVERSITY MEDICAL CENTERStudy Shows Where Alzheimer's Starts and How It Spreads
December 22, 2013
"Using high-resolution functional MRI (fMRI) imaging in patients with Alzheimer's disease and in mouse models of the disease, Columbia University Medical Center (CUMC) researchers have clarified three fundamental issues about Alzheimer's…" [read more]
CHICAGO TRIBUNEVideo games may help fend off senior moments
November 27, 2013
"At age 70, Allan S. is not a gamer, but when his time comes to play Space Fortress for a Columbia study on the aging brain, he eagerly takes his seat in front of a computer monitor…" [read more]
HEADLINES & GLOBAL NEWSNew Method Could Predict When Alzheimer's Patients Will Need Extensive Assistance, Pass Away
By Rebekah Marcarelli
November 7, 2013
"A new method could predict the distance in time between when an individual is diagnosed with Alzheimer's to when they will need extensive assistance." [read more]
Also covered by: MEDICAL XPRESS and CUMC
CBS NEWS11 new gene variants linked to Alzheimer's disease
By Michelle Castillo
October 28, 2013
"In the largest genetic analysis of Alzheimer's ever completed, scientists have discovered 11 new genes that may be tied to the late-onset form of the dementia…" [read more]
ASSOCIATED PRESSScientists find clue to age-related memory loss
By Lauran Neergaard
August 28, 2013
"Scientists have found a compelling clue in the quest to learn what causes age-related memory problems, and to one day be able to tell if those misplaced car keys are just a senior moment or an early warning of something worse." [read more]
Also covered by: NPR: All Things Considered, REUTERS,U.S. NEWS & WORLD REPORT, BLOOMBERG NEWS, NEW YORK DAILY NEWS, HEALTHDAY NEWS, HUFFINGTON POST, HEALTH CENTRAL, and UNIVERSITY HERALD.
NPRNew Alzheimer's Research Could Lead To Treatments
By Carey Goldberg
July 25, 2013
"A new report in the journal Nature shows a significant step forward in figuring out what causes things to go wrong in the brain early on in Alzheimer's disease…" [read more]
Also covered by: WBUR RADIO (NPR, Boston, MA), GENOME WEB, EVERYDAY HEALTH, RED ORBIT, PRENSA LATINA, MEDICAL NEWS TODAY, MEDILEXICON, MEDICAL XPRESS, BIOSCIENCE TECHNOLOGY, TELESUR TV, EUROPA PRESS, ABC.ES, and JAKARTA GLOBE.
BLOOMBERG NEWSPath of Alzheimer's Disease Risk Gene Tracked, Scientists Say
By Elizabeth Lopatto
July 24, 2013
"Scientists mapped the step-by-step actions that lead to late-onset Alzheimer's disease…" [read more]
DIVERSE EDUCATION.COMN.C. A&T Alzheimer's Study Targets Blacks, The Group Most Affected by the Disease
By Katti Gray
July 16, 2013
"… study aims to discover why Alzheimer's strikes Blacks more than any other racial group in the United States." [read more]
REUTERSCould family longevity protect against dementia?
By Andrew M. Seaman
May 6, 2013
"It's not necessarily that these individuals never become cognitively impaired, but what it seems like is that there is a delayed onset of cognitive impairment," said Stephanie Cosentino, of the Columbia University Medical Center in New York. [read more]
BLOOMBERG BUSINESSWEEKAlzheimer's: The Costliest Killer
By Peter Coy
April 25, 2013
"In 2006 former television journalist Meryl Comer described in the Alzheimer's & Dementia journal what it's like to care for a husband with early-onset Alzheimer's disease …" [read more]
CBS NEWSAlzheimer's gene ABCA7 linked to increased disease risk in African-Americans
By Ryan Jaslow
April 10, 2013
"A new study has revealed that a gene that was once thought to be weakly associated with Alzheimer's disease risk in white people may almost double the risk of developing the debilitating neurological disease when it's present in African-Americans…" [read more]
Also covered by:
NBC NEWS: Study Finds Gene that May Raise Alzheimer's Risk in Blacks
USA TODAY: Gene Linked to Higher Alzheimer's Risk in Blacks
NEW YORK TIMES: In Blacks, Alzheimer's Study Finds Same Variant Genes as in Whites
BLOOMBERG NEWS: Gene Doubles Risk of Late-Onset Alzheimer's in Blacks
REUTERS: Study Finds Gene that may Raise Alzheimer's Risk in Blacks
WNYC RADIO: Study Finds Black and White Alzheimer's Patients Share Genes Variants
HEALTHDAY NEWS: Gene May Double Risk of Alzheimer's in Blacks
MEDPAGE TODAY: Gene Mutation in Blacks May Raise Alzheimer's Risk
ALZHEIMER RESEARCH FORUM: AD GWAS in African Americans Confirms, Reshuffles AlzGene List
PBS NEWSHOURAssessing Your Risk of Alzheimer's Disease
By Michelle Andrews and Kaiser Health News
April 4, 2013
"Alzheimer's disease can't be prevented or cured, and it ranks second only to cancer among diseases that people fear…" [read more]
HEALTH NEWS DIGESTDepression in Alzheimer's Patients Associated with Declining Ability to Handle Daily Activities
March 19, 2013
"More symptoms of depression and lower cognitive status are independently associated with a more rapid decline in the ability to handle tasks of everyday living…" [read more]
Also covered by:
DAILY RX: Depression Put Alzheimer's on Fast Track
MEDPAGE TODAYBrain Lesions May Play Role in Alzheimer's
January 23, 2013
"In a cohort of participants in the Alzheimer's Disease Neuroimaging Initiative, the two factors were independent predictors of Alzheimer's disease, according to Adam Brickman, PhD, of Columbia University…" [read more]
Also covered by:
HEALTH CANAL.COM: It's Not Just Amyloid: White Matter Hyperintensities and Alzheimer's Disease
DISCOVERFour Steps Against Alzheimer's
By Linda Marsa
January 23, 2013
"Alzheimerâ€™s disease has repeatedly defeated predictions that effective treatments were right around the corner. … But several 2012 advances improve the prospects for intervening …" [read more]
CARING FOR THE AGESDiscontinuing Risperidone?
By Mary Ann Moon
January 22, 2013
"Among patients with Alzheimer's disease who develop psychosis or agitation-aggression that responds to risperidone, discontinuing the drug as advised after 3-6 months is associated with a doubling of the rate of relapse…" [read more]
- Arlene Lawton, RN has been selected to receive the 2012 P&S Award for Excellence in Research. As her many nomination letters attest, Arlene "has been an example of excellence in research for over 20 years." As a research nurse at the Alzheimer's Disease Research Center (ADRC), coordinator for our Brain Donation program, and senior staff associate in the Taub Institute, Arlene has made a "lasting impression on countless individuals," "broaching difficult topics with extraordinary grace," and treating patients and colleagues alike with "genuine warmth and kindness" in a "poised and professional" manner.
- Dr. Yaakov Stern was one of several notable panelists to participate in the Alzheimer's Association Annual Meeting presentation, "Crosswords, Computers, and Cognition: What's Going on in Your Brain?", now available online. With nearly 400 people crowding the Times Center auditorium, this event was the most well-attended in the New York City chapter's history.
- Dr. Larry Honig's recent Archives of Neurology publication on telomere length is the subject of CUMC's latest Research Capsule. [read more]
- "Researchers in the Taub Institute at Columbia University Medical Center (CUMC) have identified a mechanism that appears to underlie the common sporadic (non-familial) form of Parkinson's disease…" [read more]
- Dr. Manly's work on the "Early Detection of Alzheimer's among Diverse Populations" is the topic of Columbia University Medical Center's Research Capsule.
- Drs. Wai Haung Yu and Jessica Wu of the Taub Institute received awards from the American Health Assistance Foundation for "Tau Homeostasis Via Proteasomal & Autophagic Activity" and "Conformation-Dependent Uptake and Secretion of Tau," respectively.
- Frontotemporal Dementia (FTD) is a group of poorly-understood, frequently misdiagnosed brain diseases that can result in drastic personality changes in affected individuals. Columbia Neurology FTD expert Dr. Edward Huey and Genetic Counselor Jill Goldman were recently featured in an in-depth New York Times article titled, "When Illness Makes A Spouse A Stranger," which chronicles one couple's courageous battle with this devastating neurological disorder.
- A new study by Dr. Nikolaos Scarmeas has found that consumption of omega-3 fatty acids, plentiful in fish and nuts, is associated with lower blood levels of beta-amyloid protein… read more in The New York Times.
- Dr. Scott Small and colleagues from Neurology and the Taub Institute examined the association of depressive symptoms, antidepressant use and brain volumes on MRI, in a large cohort of nondemented, elderly individuals from the Washington/Hamilton Heights-Inwood Columbia Aging Project (WHICAP). Their results, currently published online in the Journal of Alzheimer's Disease, suggest that late life depression is associated with more global brain atrophy, more atrophy of the hippocampus, and more white matter lesions, mainly driven by antidepressant use.
- Drs. Roy Alcalay, Nikolaos Scarmeas, and others from Neurology and Taub Institute found Mediterranean-style diet adherence to be associated with reduced odds for Parkinson's disease (PD). Their study, currently published in an online version of Movement Disorders, also suggests an association between higher MeDI adherence and later PD age at onset.
- Dr. Scott Small on recent developments in Alzheimer's, featured on Charlie Rose.
- Dr. Adam Brickman on "Silent Strokes Tied to Memory Loss Among Older Adults," featured on Voice of America, USA Today.
- Drs. Karen Duff, Scott A. Small, and Li Liu on "Path Is Found for the Spread of Alzheimer's," featured in The New York Times.
- Dr. Jennifer J. Manly on "US wants effective Alzheimer's treatment by 2025," featured in the Associated Press.
- The work of Dr. Scott Small and colleagues from Neurology and the Taub Institute, that implicated the polyamine pathway in Parkinson's disease pathogenesis, was highlighted in Chapter 1 of the NIH's Clinical and Translational Science Awards Progress Report 2009 – 2011. [read report]
- Dr. Adam Brickman, was selected to receive the Early Career Award from the International Neuropsychological Society. He will be delivering an award address titled "Reconsidering the Role of White Matter Disease in Cognitive Aging and Dementia" at the 40th annual meeting of the Society next month in Montreal.
- Bernadette Boden-Albala, DrPH, Department of Neurology, and Jose Luchsinger, MD, Taub Institute, have received $3.9 million over five years from the National Institute on Minority Health and Health Disparities for "Northern Manhattan Initiative for Minority Involvement in Clinical Trials (NIMICT)."
- Eric A. Schon, PhD, Lewis P. Rowland Professor of Neurology in Genetics and Development has received an award from the Alzheimer's Drug Discovery Foundation for his project, "Mitochondria-Associated Membranes in the Pathogenesis of Alzheimer's Disease: A New Target for Drug Discovery."
- Dr. Adam Brickman, has been selected to receive the 2011 Margaret M. Cahn Research Award, for his research on white matter hyperintensities in aging and Alzheimer's disease, from the Alzheimer's Association Hudson Valley/Rockland/Westchester, NY Chapter.
- Elan Louis, MD, MS, Professor of Neurology and Epidemiology answers questions on "the essentials of essential tremor" in the most recent P&S Five in Five series. [watch the video]
- Yaakov Stern, PhD, Professor of Clinical Neuropsychology in the Departments of Neurology, Psychiatry, and Psychology has been awarded a new RO1 and two 5-year renewals from the NIH for his projects: "Exploring Cognitive Aging Using Reference Ability Neural Networks"; "Predictors of Severity in Alzheimer's Disease"; and "Imaging of Cognition, Learning, and Memory in Aging."
- Edward D. Huey, MD, Assistant Professor of Psychiatry and Neurology and Jill Goldman, MS, MPhil, Genetic Counselor, both in the Taub Institute, are co-directing a CME program, "Is it Alzheimer's Disease or Frontotemporal Degeneration? An Update on Diagnosis, Management, and Research," on Monday, December 12, 12:15-4:45 PM, in the NI Auditorium.
- Scott Small, MD, Professor of Neurology in the Taub Institute and Sergievsky Center and colleagues have reviewed recent neuroimaging findings that indicate common brain disorders, from Alzheimer's disease and cognitive ageing to schizophrenia and depression, differentially target distinct functional and molecular subregions of the hippocampus, suggesting a unified pathophysiological framework of hippocampal dysfunction.
- Karen Marder, MD, MPH, Sally Kerlin Professor of Neurology and Psychiatry was appointed as one of three site investigators to serve on the Executive Committee of the NINDS NeuroNEXT project. The NeuroNEXT network of 25 sites nationwide, including Columbia in partnership with Weill-Cornell, will provide a standardized, accessible infrastructure to facilitate rapid development and implementation of protocols in adult and pediatric neurological disorders.