Taub Institute: Genomics Core
AN NIA-FUNDED ALZHEIMER'S DISEASE RESEARCH CENTER

 

Columbia University
Medical Center
Neurological Institute

710 West 168th Street, 3rd floor
(212) 305-1818


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About Us

Taub Faculty


 Andrew Sproul, PhD

Andrew Sproul, PhD

Assistant Professor of Pathology & Cell Biology
Director of the Stem Cells and Cellular Models Platform, Taub Institute

Email: aas2003@cumc.columbia.edu
Tel: 646-379-1812

Research Summary:

I am the founding Director of the Stem Cell and Cellular Models Platform at the Taub Institute for Research on Alzheimer's Disease and the Aging Brain, a core facility that was established with the goal to implement pluripotent stem cell technology as a resource for neurodegenerative and neurological disease researchers at Columbia University. Our laboratory's main focus is developing robust differentiation protocols for large-scale production of disease-relevant neurons and other CNS cell types, and using gene-editing strategies to create allelic series of isogenic disease and control pluripotent stem cell (PSC) lines. These tools will greatly aid mechanistic studies of disease mechanisms and provide a better platform for therapeutic screening. In addition to partnering with a variety of Taub investigators on disease-related research, our laboratory is interested in elucidating novel mechanistic links between aberrant APP processing and Tau dysregulation.

Education and Training:

PhD: Columbia University, 2008




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