Taub Institute: Genomics Core
AN NIA-FUNDED ALZHEIMER'S DISEASE RESEARCH CENTER

 

Columbia University
Medical Center
Neurological Institute

710 West 168th Street, 3rd floor
(212) 305-1818


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About Us

Taub Faculty

Catherine Marquer, PhD

Catherine Marquer, PhD

Assistant Professor of Pathology and Cell Biology (in the Taub Institute) at the CUMC

Email: cm3244@cumc.columbia.edu

Dr. Catherine Marquer received her PhD from University Pierre and Marie Curie (Paris, France). From 2008 to 2012, she trained as a post-doctoral researcher in the Brain and Spine Institute (Paris, France). She then joined Columbia University for a second post-doctoral experience. In 2016, she became a Faculty member of the Department of Pathology and Cell Biology and the Taub Institute for Research on Alzheimer’s Disease and the Aging Brain at Columbia University.

Dr. Marquer is a cellular neurobiologist who focuses on the analysis of healthy vs. diseased neuronal function through understanding of basic cell biology, with a strong emphasis on the lipid signaling / endo-lysosomal trafficking interaction. She is specifically interested in the pathogenesis of Alzheimer's disease (AD) and related disorders (Down Syndrome, Niemann-Pick type C, traumatic brain injury). She has contributed to the delineation of early molecular dysregulations –e.g. cholesterol modifications- leading to Alzheimer's disease onset. Her long-term objective is to provide key information on the progression and possible treatment of these disorders. Dr Marquer’s translational approach combines in vitro (cell lines and cultured neurons) and in vivo (transgenic mice) model systems as well as human material from controls and patients. Her lab studies these systems using a wide array of microscopies (confocal, super-resolution, spinning-disk) as well as biochemical techniques (western blots, lipidomics, phosphoinositide quantification by HPLC).


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