Taub Institute: Genomics Core
AN NIA-FUNDED ALZHEIMER'S DISEASE RESEARCH CENTER

 

Columbia University
Irving Medical Center
Neurological Institute

710 West 168th Street, 3rd floor
(212) 305-1818


bottom bar
top
make an appointment

About Us

Taub Faculty

Catherine Marquer, PhD

Catherine Marquer, PhD

Assistant Professor of Pathology and Cell Biology (in the Taub Institute) at the CUMC

Email: cm3244@cumc.columbia.edu

Research in my lab focuses on the analysis of healthy vs. diseased neuronal function with a strong emphasis on the lipid signaling / endo-lysosomal trafficking interaction. We are specifically interested in Alzheimer’s disease (AD) and related disorders (Down Syndrome, Niemann-Pick type C, traumatic brain injury). Our general strategy is to delineate early molecular dysregulations leading to Alzheimer’s disease onset in order to provide key information on the disease progression and its possible treatment. Our translational approach combines in vitro (cell lines and cultured neurons) and in vivo (transgenic mice) model systems as well as human material from controls and patients. We study these systems using a wide array of microscopies (confocal, super-resolution, spinning-disk) as well as biochemical techniques (western blots, lipidomics, phosphoinositide quantification by HPLC).


bottom bar