Gertrude H. Sergievsky Center
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Faculty and Administrative Staff


Lawrence S. Honig, MD, PhD

Lawrence S. Honig, MD, PhD

Sergievsky Center
630 West 168th Street
New York, New York 10032

Tel: (212) 305-9194
Fax: (212) 305-2526
Email: lh456@columbia.edu
Lawrence Honig is an Associate Professor of Clinical Neurology in the Gertrude H. Sergievsky Center, the Taub Institute for Research on Alzheimer's Disease and the Aging Brain, and in the Department of Neurology, Division of Aging and Dementia. He is the Director of the Clinical Core of the Alzheimer's Disease Research Center at Columbia University. He is also an Associate Attending in Neurology at New York Presbyterian Hospital and holds appointments at the New York State Psychiatric Institute, and Isabella Geriatric Center.

Biographical Sketch

Dr. Honig received his A.B. /cum laude/ in Biological Sciences from Cornell University (Ithaca, NY) College of Arts and Sciences, and his Ph.D. in Molecular Biology from the University of California, Berkeley (California). He subsequently obtained his M.D. from the University of Miami (Florida). His postgraduate medical training included internship in Medicine, followed by residency training in Neurology, both at Stanford University Medical Center (California). He was a Clinical Instructor and then Clinical Assistant Professor at Stanford University Medical Center, prior to moving in 1994 to take a position as Assistant Professor in the Department of Neurology at the University of Texas Southwestern Medical Center in Dallas (Texas), where he was also a Senior Investigator and the Neuroscience Research Coordinator in the Dallas Alzheimer's Disease Center. In the year 2000, he moved to his present position as Associate Professor of Clinical Neurology at Columbia University College of Physicians and Surgeons, where he is involved in clinical and research activities in the Sergievsky Center, the Taub Institute, and the Alzheimer's Disease Research Center. He has received a number of grants and honors, including Anna Fuller Fund and Walter V. & Idun Berry Fellowships, the UTSW Distinguished Young Research Award (1995), and the Ornish Award in Alzheimer's Disease Research (1999). He is a Diplomate in the specialty of Neurology (American Board of Psychiatry and Neurology), and holds subspecialty certification in Behavioral Neurology and Neuropsychiatry (United Council for Neurological Subspecialties). He is an Associate Editor of Archives of Neurology. He is an Active Member of the American Neurological Association and a Fellow of the American Academy of Neurology. He is a member of a number of other medical and scientific organizations, including Sigma Xi Scientific Society and the American Association for the Advancement of Science.

Summary of Activities

Dr. Honig's major interests are in dementia and neurodegenerative disease, including molecular, genetic, geriatric, epidemiologic, and behavioral aspects of neurology. His activities include patient care, clinical research, and laboratory-based research addressing aging and nervous system degeneration. Dr. Honig's clinical care activities include evaluation and treatment of memory and language dysfunction, and other cognitive and behavior changes in adults, and include providing consultations at the Columbia campus of New York Presbyterian Hospital, and office-based care at the Neurological Institute on West 168th Street and at Columbia University Medical Center. Dr. Honig's clinical research activities include directing the efforts of the clinical core of the Alzheimer's Disease Research Center at Columbia University, and various clinical research projects involving Alzheimer's disease, Parkinson's disease, cerebrovascular effects on cognition, frontotemporal and corticobasal degeneration, and essential tremor, using epidemiological, laboratory and neuroimaging modalities. Dr. Honig's laboratory-based research principally concerns developing biomarkers for neurodegenerative disease, and using molecular biological tools to analyze gene expression and tissue changes in aging and human brain diseases. Two major areas of interest are and assessing regional and molecular variation in gene expression in different neurodegenerative diseases, and determining the role of chromosomal telomere length as a marker for biological aging.





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Sergievsky Center
630 West 168 St. New York, NY 10032
Phone: 212-305-2515 • Fax: 212-305-2426

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Last updated: January 9, 2013
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