Gertrude H. Sergievsky Center
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Faculty and Administrative Staff


Sylvie Goldman, PhD

Sylvie Goldman, PhD

Columbia University Medical Center
622 West 68th Street, PH 18-331
New York, NY 10032

Email: sg3253@cumc.columbia.edu

Biographical Sketch

Sylvie Goldman is an Assistant Professor of Neuropsychology in the Department of Neurology (Division of Child Neurology) and at the Gertrude H. Sergievsky Center.

Sylvie Goldman graduated from the Université Libre de Bruxelles, Belgium with a degree in Clinical and Industrial Psychology and Pedagogical Sciences. She obtained her PhD in Developmental Psychology from the City University of New York Graduate Center (CUNY). She published several articles from her dissertation work on autobiographical memory in children with autism spectrum disorders. She was a post-doctoral student under the mentorship of Isabelle Rapin at Albert Einstein College of Medicine in the department of Neurology (Child Neurology) and a LEND fellow - Leadership Education in Neurodevelopmental and Related Disabilities-fellow at the Kennedy Center. In addition to her research Dr. Goldman maintains her clinical activities administering diagnostic batteries for young children with developmental disorders including autism, Rett syndrome, and language disorders. Concomitantly to her research she worked for 8 years as a clinical psychologist at the McCarton Center for developmental pediatric in Manhattan. Before joining Columbia University in the Fall of 2014 she was the co-director of the NIH Human Clinical Phenotype Core of the Rose F Kennedy Intellectual Developmental Disabilities Research Center (RFK-IDDRC) at Albert Einstein College of Medicine, Bronx.

Ongoing Research Interests

My primary interests involve understanding the neuropathophysiology correlates of autism spectrum disorders (ASD) with regard to sensorimotor functioning in relationship with cognitive profiles. I have developed and published a video analysis scoring system for motor stereotypies in children with developmental disorders including ASD and Rett Syndrome. In view of the high prevalence (~85%) of motor impairments in children with ASD I am also developing collaborative projects with biomedical engineer and physical therapist to develop novel quantifiable and reliable measures to assess motor behaviors. In the context of the lack of objective and sensitive tools to measure treatment response in behavioral and pharmacological clinical trials in autism our goal is to develop and validate novel automated outcome motoric measures (e.g., gait, repetitive movements). These new metrics would help us refine the autism phenotype and implement new motor subtypes based on measurable characteristics.

Other Research Interests

My second line of research is at the intersection of clinical developmental psychology and social sciences and addresses the role of sex and gender differences in the diagnosis of children with ASD. Two major facts are affecting ASD research. First, epidemiological studies are reporting a significant increase in the diagnosis of ASD mainly due to better identification and change in diagnosis criteria. Second, genetic research is identifying more and more risk genes for ASD. My interest centers around the established yet poorly understood male to female ratio of 4:1 and the complex biological and social factors embedded in the diagnosis process. Clinical diagnosis of ASD are based solely on behavioral assessments using gendered biased instruments to measure deviation from the norms. However, females and males are not presenting and/or compensating for their symptoms the same way. The recognition of gender-based phenotypes may contribute to more accurate diagnosis ascertainment.

Representative Publications

Goldman, S (2008). Brief Report: Narratives of Personal Events in Children with Autism and Developmental Language Disorders: Unshared Memories. Journal of Autism and Developmental Disorders, 38, 1982-1988, 2008.

Goldman, S., Salgado, M., Wang, C., Kim, M., Greene, P., Rapin, I. (2009). Motor stereotypies in preschool children with autism and other developmental disorders, Developmental Medicine and Child Neurology, 51. 30-38.PMID: 19087102

Pfaff, D., Rapin, I., Goldman, S. (2011). Male Predominance in Autism: Neuro- endocrine influences on arousal and social anxiety. Autism Research, 4, 1-14, 2011. PMID: 21465671

LeMonda, B.C., Holtzer, R., Goldman, S. (2012). Relationship between executive functions and motor stereotypies in children with autistic disorder. Research in Autism Spectrum Disorders, 6(3), 1099–1106. PMID: 23637708

Goldman, S., Temudo, T. (2012). Hand stereotypies distinguish Rett syndrome from Autism Disorder. Movement Disorders. Movement Disorders, Jul;27(8):1060-1062. PMID: 22711266

Goldman, S., O’ Brien, L. M., Filipek, P.A., Rapin, I., Herbert, M. R. (2013) Motor stereotypies and volumetric brain alterations in children with autistic disorder. Research in Autism Spectrum Disorders, 7(1), 82-92. PMID: 23637709

Goldman, S., Greene, P. (2013). Perspective: Stereotypies in autism: a video demonstration of their clinical variability. Frontiers in Integrative Neuroscience. Research Topic: Autism: The Movement Perspective. January (6). PMID: 23316144

Goldman, S.
(2013) Opinion: Sex, gender, and the diagnosis of autism - A biosocial view of the male preponderance". Research in Autism Spectrum Disorders 7(6), 675–679. PMID: 23687516

Goldman, S., DeNigris, D (2014). Parents’ Strategies to Elicit Autobiographical Memories in Autism Spectrum Disorders, Language Disorders and Typically Developing Children. Journal of Autism and Developmental Disorders Oct 14. [Epub ahead of print]. PMID: 25312278




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Last updated: June 16, 2016
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