CUMC
Department of Radiation Oncology

Faculty

Eileen P. Connolly, M.D., Ph.D.

Eileen Connolly, MD, PhDEileen P. Connolly, MD, PhD
Assistant Professor in Clinical Radiation Oncology

Columbia University College of Physicians and Surgeons


Areas of Expertise:
Pediatric Cancer
Brain                                                     
Gamma Knife
Lymphoma & Hematologic Malignancies
Sarcoma
Breast

Credentials:

TYPE INSTITUTION
Medical School   New York University School of Medicine
Internship   New York University School of Medicine
Residency   New York University School of Medicine

Primary Practice Location:

New York Presbyterian Hospital and Columbia University Medical Center (NYP-CUMC)
Department of Radiation Oncology
622 West 168th Street
New York, NY 10032

Phone: (212) 305-5050
Fax: (212) 305-5935

Recent Publications:

Connolly, E., Braunstein, S., Formenti, S., and Schneider, R.J.  Hypoxia inhibits protein synthesis through a 4E-BP1 & elongation factor 2 kinase pathway controlled by mTOR and uncoupled in breast cancer cells. Mol Cell. Biol. 2006 May; 26(10):3955-65.

Connolly, E, Thuiller, V., Rouy, D., Bouetard, G., and Schneider, R.J. Inhibition of Cap-Initiation complexes linked to a novel mechanism of eIF4G depletion in acute myocardial ischemia. Cell Death and Diff. 2006 Sept;13(9):1586-94.

Ioffe E, Moon B, Connolly E, Friedman JM. Abnormal regulation of the leptin gene in the
pathogenesis of obesity. Proc. Natl. Acad. Sci. USA 1998; 95:11852-7.

Li C, Ioffe E, Fidahusein N, Connolly E., Friedman J.M. Absence of soluble leptin receptor in plasma from dbPas/dbPas and other db/db mice.J Biol Chem. 1998. 273:10078-82.

Hung CF, Holzmacher R, Connolly E, Berenbaum MR, Schuler MA. Conserved promoter elements in the CYP6B gene family suggest common ancestry for cytochrome P450 monooxygenases mediating furanocoumarin detoxification. Proc. Natl. Acad. Sci. USA 1996.93:12200-5.

Abstracts & Presentations:

Connolly E.P., Silvera D., Badura, M.L., Venuto T.A., Schneider R.J. (2011). Over-expression of translation initiation factor eIF4G confers robust radioresistance to the cancer stem cell population in inflammatory breast cancer. American Society for Therapeutic Radiology and Oncology (ASTRO) 53nd Annual Meeting, Miami, FL – Oral presentation

Connolly E.P., Silvera D., Venuto T.A., Sawai R., Schneider R.J. (2011). TORC1/2 inhibition with concurrent radiation controls inflammatory breast cancer in a preclinical animal model through selective blockade of translation. American Society for Therapeutic Radiology and Oncology (ASTRO) 53nd Annual Meeting, Miami, FL – Poster

Connolly E.P., Silvera D., Venuto T.A., Formenti S.C., Schneider R.J. (2011). Catalytic but not allosteric inhibition of mTOR radiosensitizes inflammatory breast cancer tumors in an animal model. AACR special conference – Targeting PI3K/mTOR signaling in Cancer, San Francisco, CA – Poster

Silvera D., Connolly E.P., Badura, M.L., Venuto T.A., Schneider R.J. (2011). Translation initiation factor eIF4G confers radio-resistance to the cancer stem cell population in advanced breast cancers. AACR special conference – Targeting PI3K/mTOR signaling in Cancer, San Francisco, CA – Poster

 

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