CUMC
Department of Radiation Oncology

Faculty

Simon K. Cheng, M.D., Ph.D.

Tony Wang

  • New Patients Tel – 212 305-5050
  • Administrative Office Tel – 323 305-7077
  • Fax – 212-305-5935

Outpatient Office Location

  • The Irving Radiation Oncology Center
  • Columbia University Medical Center
  • 622 West 168th Street,
  • New York, NY 10032

Physician Summary

Simon Cheng, M.D., Ph.D. is Assistant Professor of Radiation Oncology at NewYork-Presbyterian/Columbia University Medical Center and Director of the Radiation Oncology Residency Program. Dr. Cheng cares for patients with all types of cancer, with a special interest in Lung, Brain, Esophagus and Spine cancers. He is an expert on stereotactic radiosurgery including Gamma Knife radiosurgery, body radiosurgery of lung and spine. Dr. Cheng is widely recognized amongst his peers as a leading research scientist at New York Presbyterian/Columbia University Medical Center. His ongoing research trials relating to the treatment of thoracic cancers is to enhance overall treatment outcomes for the patient. Dr. Cheng received his M.D./Ph.D. degree from New York University School of Medicine. He then received his preliminary internal medicine training at St. Mary’s Medical Center, San Francisco. Dr. Cheng received his radiation oncology training at New York University School of Medicine, where he was on the ABR Holman Research Pathway, an intensive research-focused honors program.

Dr. Cheng is the director of his thoracic radiation oncology research laboratory at Columbia University, and was the recipient of the highly prestigious ASCO Conquer Cancer Foundation Young Investigator Award in 2010. His current research is supported by the Louis V. Gerstner, Jr. Scholar Award for his study of “Immunomodulation of Thoracic Radiation Therapy”, and the LUNGevity Foundation Targeted Therapeutics Award “Identification of Predictive Biomarkers of Chemoradiotherapy in Lung Cancer”. He has numerous publications in his area of expertise and is a Journal Reviewer for “The Journal of Radiation Research”. r. Cheng was Gamma Knife Radiosurgery trained at the University of Pittsburgh Medical Center - Center for Image-Guided Neurosurgery, pioneers in the field of stereotactic radiosurgery for brain cancers and malformations.

Dr. Cheng is very involved in residency education and serves as Director of the Radiation Oncology residency program. He is a member of numerous committees and is an Investigator for RTOG, a nationally recognized organization for clinical trials.

Clinical Expertise

  • Lung / Thoracic cancers
  • Brain cancers / Brain benign lesions
  • Spine tumors
  • Esophageal cancers
  • Gamma Knife Stereotactic Radiosurgery
  • Stereotactic Radiosurgery of the Body (SBRT)

Board Certifications

  • Radiation Oncology

Appointments

  • Assistant Professor of Radiation Oncology at Columbia University Medical Center

Education

  • M.D. /Ph.D., New York University School of Medicine

Internship and Residency

  • Internal Medicine, St. Mary’s Medical Center, San Francisco
  • Radiation Oncology, New York University School of Medicine

Publications

Wang TJ, Saad S, Qureshi YH, Jani A, Isaacson SR, Sisti MB, Bruce JN, McKhann GM 2nd, Lesser J, Cheng SK, Clifford Chao KS, Lassman AB. Outcomes of gamma knife radiosurgery, bi-modality & tri-modality treatment regimens for patients with one or multiple brain metastases: the Columbia University Medical Center experience. J Neurooncol. 2015 Feb 17.


Horowitz DP, Wang TJ, Wuu CS, Feng W, Drassinower D, Lasala A, Pieniazek R,Cheng S, Connolly EP, Lassman AB. (2014) Fetal radiation monitoring and dose minimization during intensity modulated radiation therapy for glioblastoma in pregnancy.J Neurooncol. 2014 Nov;120(2):405-9.


Berry SL, Polvorosa C, Cheng S, Deutsch I, Chao KS, Wuu CS.(2013) Initial Clinical Experience Performing Patient Treatment Verification With an Electronic Portal Imaging Device Transit Dosimeter. Int J Radiat Oncol Biol Phys. 88: 204–209.


Wang TJC, Chang C, Wei Y, Horowitz DP, Connolly EP, Cheng SK, Feng WZ, Chao KSC, Deutsch I. (2013) Comparison of effects of rectal volume delineation methods on dose constraint endpoints in the treatment of prostate cancer with intensity-modulated radiation therapy. J Radiat Oncol. DOI 10.1007/s13566-013-0104-9


Wang TJC, Menda Y, Cheng SK, Wu CC, Lee NY. (2012) New Tracers PET in Head and Neck Squamous Cell Carcinoma. PET Clinics 7: 431-441.


Wang TJC, Riaz N, Cheng SK, Lu JJ, Lee NY. (2012) Intensity-Modulated Radiation Therapy for Nasopharyngeal Carcinoma: A Review. Journal of Radiation Oncology 1:129-146.


Wen G, Hong M, Li B, Liao W, Cheng SK, Hu B, Calaf GM, Lu P, Partridge MA, Tong J, Hei TK. (2011) Transforming growth factor-β-induced protein (TGFBI) suppresses mesothelioma progression through the Akt/mTOR pathway. Int J Oncol 39:1001-1009.


Wen G, Partridge MA, Li B, Hong M, Liao W, Cheng SK, Zhao Y, Calaf GM, Liu T, Zhou J, Zhang Z, Hei TK. (2011) TGFBI expression reduces in vitro and in vivo metastatic potential of lung and breast tumor cells. Cancer Lett 308: 23-32.


Bennett JT, Joubin K, Cheng S, Aanstad P, Herwig R, Clark M, Lehrach H, Schier AF (2007) Nodal signaling activates differentiation genes during zebrafish gastrulation. Dev Bio 304: 525-540.


Cheng SK, Olale F, Brivanlou AH, Schier AF (2004) Lefty blocks a subset of TGFβ signals by antagonizing EGF-CFC coreceptors. PLoS Biology 2: 215-226.


Cheng SK, Olale F, Bennett JT, Brivanlou AH, Schier AF (2003) EGF-CFC proteins are essential coreceptors for the TGFβ signals Vg1 and GDF1. Gen Dev 17: 31-36.


Gritsman K, Zhang J, Cheng S, Heckscher E, Talbot WS, Schier AF. (1999) The EGF-CFC protein One-eyed pinhead is essential for Nodal signaling. Cell 97: 121–132.


Chung S, Licong J, Cheng S, Furneaux H (1996) Purification and properties of HuD, a Neuronal RNA-binding protein. J Biol Chem 271:11518-11524.


Ma WJ, Cheng S, Campbell C, Wright A, Furneaux H (1996) Cloning and characterization of HuR, a ubiquitously expressed Elav-like protein. J Biol Chem 271:8144-8151.


Chung S, Licong J, Cheng S, Furneaux H (1996) Purification and properties of HuD, a Neuronal RNA-binding protein. J Biol Chem 271:11518-11524.


Gritsman K, Zhang J, Cheng S, Heckscher E, Talbot WS, Schier AF. (1999) The EGF-CFC protein One-eyed pinhead is essential for Nodal signaling. Cell 97: 121–132.


Cheng SK, Olale F, Bennett JT, Brivanlou AH, Schier AF (2003) EGF-CFC proteins are essential coreceptors for the TGFß signals Vg1 and GDF1. Gen Dev 17: 31-36.


Cheng SK, Olale F, Brivanlou AH, Schier AF (2004) Lefty blocks a subset of TGFß signals by antagonizing EGF-CFC coreceptors. PLoS Biology 2: 215-226.


Bennett JT, Joubin K, Cheng S, Aanstad P, Herwig R, Clark M, Lehrach H, Schier AF (2007) Nodal signaling activates differentiation genes during zebrafish gastrulation. Dev Bio 304: 525-540.

 

  • Residency/Medical Education
  • Advanced Technology
  • Patients
  • CUMC Scene