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The complete 1999 annual report can be
downloaded as a PDF as can individual sections of this report from the
links below. The table of contents is given below.
For annual reports from previous years click here.
Physics, Biophysics, and Risk Estimation [PDF]
Technical
Characteristics of the Columbia University Single-Ion Microbeam
Gerhard Randers-Pehrson, Charles R. Geard, Gary W. Johnson, and David
J. Brenner
Electrostatic Lens Design for the Columbia Microbeam
Alexander D. Dymnikov, David J. Brenner, Gary Johnson, and Gerhard
Randers-Pehrson
The
Low-Energy Neutron Facility
Stephen A. Marino, Dusan Srdoc, and Gary W. Johnson
Risks
from Less than 10 Millisievert: What Do We Really Know? How Can We Learn
More?
David J. Brenner
The Risk
of Fatal Cancer from Pediatric Computed Tomography
David J. Brenner, Carl D. Elliston, Eric J. Hall, and Walter E.
Berdon
A
Polymer, Random Walk Model for the Size-Distribution of Large DNA
Fragments After High-LET Radiation
David J. Brenner, with Artem Ponomarev and Rainer Sachs, and Lynn
Hlatky
Microbeam: Cellular Studies [PDF]
Induction of a Bystander Mutagenic Effect of Alpha Particles on
Mammalian
Hongning Zhou, Gerhard Randers-Pehrson, and Tom K. Hei
Intra- and Inter-Cellular Reponses Following Cell-Site-Specific
Microbeam Irradiation
Charles R. Geard, Gerhard Randers-Pehrson, Stephen A. Marino, Gloria
Jenkins-Baker, Tom K. Hei, Eric J. Hall, and David J. Brenner
Single Alpha-Particle Traversals and Tumor Promoters
Richard C. Miller, Satin Sawant, Gerhard Randers-Pehrson, Stephen A.
Marino, Charles R. Geard, Eric J. Hall, and David J. Brenner
Bystander Effect of Radiation on Oncogenic Transformation
Satin G. Sawant, Gerhard Randers-Pehrson, Charles R. Geard, and Eric
J. Hall
Role of Oxyradicals in DNA Damage Induced by Cytoplasmic Irradiation in
Mammalian Cells
An Xu, Gerhard Randers-Pehrson, and Tom K. Hei
Cellular Studies [PDF]
RBE and Microdosimetry of Low-Energy X Rays
Stephen A. Marino, Dusan Srdoc, Satin Sawant, Charles R. Geard, and
David J. Brenner, in collaboration with Zugen Fu
Establishment of an Alpha-Particle-Induced Estrogen-Dependent Breast
Cancer Model
Gloria M. Calaf and Tom K. Hei
Genotoxicity Versus Carcinogenicity: Implications From Fiber Toxicity
Studies
Tom K. Hei, An Xu, Darren Louie, and Yong-Liang Zhao
Induction of Reactive Oxygen Species by Crocidolite Asbestos in
Mammalian Cells
An Xu and Tom K. Hei
Focal Adhesion Motility Revealed in Stationary Fibroblasts
Lubomir B. Smilenov with Alexei Mikhailov, and Robert J. Pelham, Jr.,
Eugene E. Marcantonia, and Gregg G. Gundersen
Transformation of Human Bronchial Epithelial Cells by the
Tobacco-Specific N-Nitrosamine, NNK
Hongning Zhou and Tom K. Hei
Protein Expression in Tumorigenic Human Breast Epithelial Cells
Transformed by Alpha Particles
Gloria M. Calaf and Tom K. Hei
Microsatellite Instability in Tumorigenic Human Bronchial Epithelial
Cells Induced by Alpha Particles and Fe-56 Ions
Chang Q. Piao and Tom K. Hei
Malignant Transformation of Human Bronchial Epithelial Cells by Arsenite
Chang Q. Piao and Tom K. Hei
Radon, Arsenic, and Mutagenesis
Su X. Liu and Tom K. Hei
Cytogenetic Studies [PDF]
Chromosomal Aberrations in Tumorigenic Human Bronchial Epithelial Cells
Transformed by Chrysolite Asbestos
Masao Suzuki, Chang-Qing Piao, and Tom K. Hei
Cytogenetic Effects of Heavy-Ion Beams in Normal Human Bronchial
Epithelial Cells
Masao Suzuki, Chang-Qing Piao, and Tom K. Hei
Molecular Studies: Cell-Cycle Checkpoints
[PDF]
Physical Interactions Among Human Checkpoint Control Proteins HHUS1p,
HRAD1p, and HRAD9p, and Implications for the Regulation of Cell-Cycle
Progression
Haiying Hang and Howard B. Lieberman
Two-Hybrid Interactions Between the Human HRAD9p Checkpoint Control
Protein and the Tumor Suppressor p53
Sarah J. Rauth, Wei Zheng, and Howard B. Lieberman
Defective G2 Checkpoint by Inactivation of 14-3-3 Gene Influences
Telomere Function
Sonu Dhar, Jain Kaung, Jeremy A. Squire, Charles R. Geard, Raymund J.
Wellinger, and Tej K. Pandita
Molecular Studies: Damage
Responsiveness [PDF]
Ionizing Radiation Activates ATM Kinase Throughout the Cell Cycle
Tej K. Pandita, Howard B. Lieberman, Dae-Sik Lim, Sonu Dhar, Wei Zhen,
Yoichi Taya, and Michael B. Kastan
Ataxia Telangiectasia: Chronic Activation of Damage-Responsive Functions
is Reduced by Alpha-Lipoic Acid
Magtouf Gatei, Dganit Shkedy, Kum Kum Khanna, Tamar Uziel, Yosef Shiloh,
Tej K. Pandita, Martin F. Lavin, and Galit Rotman
Activation of Abl Tyrosine Kinase by Ionizing Radiation Requires ATM But
Not DNA-PK
Sanjeev Shangary and Tamara Lataxes, Tej K. Pandita, Guillermo E.
Taccioli, and R. Baskaran
Atm Inactivation Results in Aberrant Telomere Clustering During Meiotic
Prophase
Tej K. Pandita, Christoph H. Westphal, Melanie Anger, Satin G. Sawant,
Charles R. Geard, Raj K. Pandita, and Harry Scherthan
Influence of ATM Function on Telomere Chromatin Structure
Lubomir Smilenov, Sonu Dhar, and Tej K. Pandita
Expression of the Catalytic Subunit of Telomerase in Developing Brain
Neurons: Evidence for a Cell-Survival-Promoting Function
Weiming Fu, Michael Killen, and Carsten Culmsee, Sonu Dhar, Tej K.
Pandita, and Mark P. Mattson
The Human Homologue of Schizosaccharomyces pombe Rad9 protein, HRAD9p,
Interacts with Bcl-2/Bcl-xL and Promotes Apoptosis
Howard B. Lieberman, Haiying Hang, Kevin Hopkins, and Wei Zheng, in
collaboration with Kiyoshi Komatsu, Toshiyuki Miyashita, Sandy Cuddeback,
Massao Yamada, and Hong-Gang Wang
Molecular Studies Oriented
Towards Cancer [PDF]
Identification of THG1 as a Potential Suppressor of Testicular
Tumorigenesis
Yuxin Yin
Molecular Mechanism of Radiation-Induced Transformation of Human
Bronchial Epithelial Cells by High-LET Radiation
Yong L. Zhao, Chang Q. Piao, and Tom K. Hei
Expression of Transforming Genes and Allelic Imbalance in Human Breast
Epithelial Cells Induced by High-LET Radiation
Debasish Roy, Gloria Calaf, and Tom K. Hei
Aberrant Hypermethylation of the 14-3-3 Gene is Associated with Gene
Silencing in Breast Cancer
Anne T. Ferguson, Ella Evron, Christopher Umbricht, Tej K. Pandita,
Heiko Hermeking, Jeffrey Marks, Andrew Futreal, Martha R. Stampfer, and
Saraswati Sukumar
Studies
Related to Radiation Therapy [PDF]
A More Robust Biologically Based Ranking Criterion for Treatment
David J. Brenner and Rainer K. Sachs
Tumor Heterogeneity and its Effect on Parameters Estimated Using the
Linear-Quadratic Model
David J. Brenner and Eric J. Hall
The Radiological Research Accelerator Facility an NIH-Supported
Resource Center [PDF]
Dir, David J Brenner, PhD, DSc; Chief Physicist, Randers-Pehrson, PhD;
Mnger, Stephen A Marino, MS
The Radiation Safety Office [PDF] |
