Masanori Ichise, M.D.

Name, Title
Contact Information
Masanori Ichise, M.D.
Professor of Clinical Radiology

Neurological Institute
Hatch Center
710 West 168th Street Mail Code: 48
New York NY 11032
Tel: +1 212 342 0721
Email: mi2193@columbia.edu

 
Biography                                 Specialty                             Publications
 

Biography

Masanori Ichise, MD, FRCPC, is Professor of Clinical Radiology at Columbia University College of Physicians and Surgeons. An internationally recognized researcher in PET and SPECT imaging of patients with neuropsychiatric disorders such as Alzheimer’s and Parkinson’s diseases, he is well known for his expertise in the quantification of imaging results. He has authored numerous articles and pioneered multiple techniques for PET/SPECT analysis of brain chemistry. Before coming to Columbia, he was Director of the Brain Molecular Imaging Program at Brigham and Women’s Hospital in Boston and conducted research at Harvard Medical School. Previously, he was a molecular imaging principal investigator at the NIH.

Specialty

Nuclear Medicine

Publications

  1. Ichise M, Kim YJ, Erami SS, Ballinger JR, Vines D, Tanaka F, Lang AE. SPECT imaging of pre- and post-synaptic dopaminergic alterations in dopa-untreated PD. Neurology 52: 1206-1214, 1999.
  2. Ichise M, Fujita M, Seibyl JP, Verhoeff NP, Baldwin RM, Zoghbi SS, Rajeevan N, Charney DS, Innis RB. Graphical analysis and simplified quantification of striatal and extrastriatal D2 receptor binding with I-123-epidepride SPECT. J Nucl Med 40: 1902-1912,1999
  3. Ichise M, Meyer JH, Yonekura Y. An introduction to PET/SPECT neuroreceptor quantification models. J Nucl Med  42:755-763, 2001.
  4. Ichise M, Toyama H, Innis RB, Carson RE. Strategies to improve neuroreceptor parameter estimation by linear regression analysis. J Cereb Blood Flow Met  22:1271-1281, 2002.
  5. Ichise M, Liow J-S, Ku J-Q, Takano A, Modell K, Toyama H, Suhara T, Innis RB, Carson RE. Linearized reference tissue parametric imaging methods: Application to PET imaging of the serotonin transporter with [11C]DASB in human brain. J Cereb Blood Flow Met 23:1096-1112, 2003 .
  6. Toyama H, Ichise M, Liow J-S, Vines DC, Modell KJ, Esaki T, Seidel J, Sokoloff L, Green MV, Innis RB. Absolute Quantification of Regional Cerebral Glucose Utilization in Mice by [18F]FDG Small Animal PET Scanning and 2-[14C]DG Autoradiography. J Nucl Med 2004; 45: 1398-1405.
  7. Ichise M, Vines DC, Gura T, Suomi SJ, Higley JD, Innis RB Effects of early life stress on [11C]DASB PET imaging of serotonin transporters in adolescent peer- and mother-reared rhesus monkeys. J Neurosci 2006; 26:4638-4643.
  8. Cannon DM, Ichise M, Fromm S,  Nugent AC,  Sciullo D,  Gandhi SK, Klaver JM, Charney DS, Manji HK, Drevets WC. Serotonin transporter binding in bipolar disorder assessed using [11C]DASB and positron emission tomography. Biolol Psychiatry 2006; 60: 207-217.
  9. Cannon DM, Ichise M, Rollis D, Klaver JM, Gandhi SK, Charney DS et al. Elevated Serotonin Transporter Binding in Major Depressive Disorder Assessed Using Positron Emission Tomography and [11C]DASB; Comparison with Bipolar Disorder. Biol Psychiatry 2007; 62:870-877.
  10. Ichise M, Cohen RM, Carson RE. Noninvasive Estimation of Normalized Distribution Volume: Application to the Muscarinic-2 Ligand [18F]FP-TZTP. J Cereb Blood Flow Met 2007 Jul 25; PMID: 17653129 [Epub ahead of print]