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Division of Pulmonary, Allergy &

Critical Care Medicine

Clinical Centers	Cardiopulmonary Sleep and Ventilatory Disorders Center Program Director: Robert C. Basner, M.D. Associate Professor of Clinical Medicine Director, Adult Pulmonary Diagnostic Unit Director, Cardiopulmonary Sleep and Ventilatory Disorders Center Address: Columbia University Medical Center 630 West 168^th Street, PH 8 Center, Room 859, New York, New York 10032 Appointments: For consultation appointments and/or polysomnographic evaluation, please call (212) 305-7591 or fax to (212) 342-4759.
Asthma Center
Cystic Fibrosis Program
Interventional Bronchoscopy and Endobronchial Therapy Center
Jo-Ann F. LeBuhn Center for Chest Disease & Respiratory Failure
John Edsall-John Wood Asthma Center
Lung Reduction
Lung Transplantation
Medical Intensive Care Unit
Pediatric Pulmonary Medicine
Pulmonary Clinic
Pulmonary Function Testing
Sleep Studies Unit
Stress Test
Tuberculosis Clinic
CPPN Physicians Network	The Sleep Center is directed by Robert C. Basner, M.D. Dr. Basner, board certified in the specialties of internal medicine, pulmonary diseases, critical care, and sleep medicine, is a nationally recognized clinician, researcher, and educator in sleep medicine and physiology, with a particular interest in ventilatory control and cardiopulmonary interactions during sleep. The Columbia University Cardiopulmonary Sleep and Ventilatory Disorders Center is a comprehensive program of the Department of Medicine, Division of Pulmonary, Allergy, and Critical Care Medicine. The Sleep Center is a state of the art clinical and research facility established by Columbia University in 2000 to provide an academic service, education, and research center for the Columbia Presbyterian medical community. The sleep center is dedicated to providing expert and compassionate care to adult and pediatric patients of all demographic and payor origins, and to fostering an academic environment emphasizing clinical and basic research, as well as the education of the Columbia Presbyterian medical community. Clinical Activities The sleep center provides both in-patient and outpatient comprehensive consultative and diagnostic services. Specific clinical problems addressed in the sleep laboratory include the wide array of breathing disorders associated with sleep such as: Obstructive Sleep Apnea Apnea and periodic breathing associated with congestive heart failure and neurologic disease Sudden Infant Death Syndrome Nocturnal Asthma Disorders of ventilation associated with obesity, chronic obstructive lung disease, and neuromuscular disorders such as muscular dystrophy and motor neuron disease The center also studies patients with excessive daytime somnolence, including: Narcolepsy disordered initiation of sleep and sleep disruption circadian rhythm disorders parasomnias movement disorders associated with sleep. The center's examination rooms and sleep facilities are located in the Presbyterian Hospital, PH -8 Center, contiguous with the adult pulmonary function testing laboratory and adjacent to the Department of Medicine and Division of Pulmonary Medicine offices. The rooms are private and comfortable with shower facilities. The center is readily accessible to the Milstein Pavillion and medical intensive care units. All equipment necessary for state of the art performance and recording of polysomnography (electroencephalographic, electromyographic, respiratory, and cardiovascular physiologic parameters) and performance of nocturnal ventilation and oxygen titration is present in the Sleep Center. Patients with a wide array of neurologic disorders, both adults and children, are studied in the sleep center, including patients with movement disorders related to sleep, parasomnias (including REM behavior disorder, linked to neurologic disorders including cerebrovascular disease), Parkinson’s Disease (whose patients are prone to an array of sleep problems), patients with cerebrovascular disease who are prone to have sleep disordered breathing, epilepsy patients suspected of nocturnal seizures, and patients with motor neuron disease and sleep related apnea and hypoventilation. Pediatric patients are seen routinely in the sleep center for parasomnias, movement disorders, excessive sleepiness and behavioral disorders associated with sleep disorders, and sleep disordered breathing associated with pulmonary hypertension, obesity, craniofacial abnormalities, congenital heart disorders, neuromuscular associated sleep apnea and hypoventilation, and adenotonsilar hypertrophy associated with sleep apnea. The sleep center maintains close clinical and research collaboration with a wide base of expert clinicians and researchers within the CPMC community, including the lung failure center, the heart failure center, the lung transplant service, rehabilitation medicine, behavioral medicine, exercise physiology, adult and pediatric otolaryngology, neurology, and pediatric pulmonary medicine, as well as with the School of Public Health, the Harlem Lung Center, the School of Dentistry, the School of Nursing, and Teacher's College. Research Activities The sleep center laboratory maintains a particular interest in investigating the physiologic contributors to chronic hypertension and the metabolic syndrome associated with sleep-disordered breathing in urban minority populations, and the study of cardiovascular perturbations associated with sleep deprivation. Autonomic analysis of heart rate and blood pressure, as well as vascular reactivity analysis, are particular interests of the laboratory. Ongoing research protocols include investigations in stress-related autonomic and vasomotor regulation in normal subjects and patients with diverse breathing disorders during sleep, sleep-related arousals, sleep deprivation, hypoxemia, and exercise; effect of respiratory frequency and volume changes during exercise on heart rate variability measurement; activity of upper airway dilator and constrictor muscles awake and during sleep related to negative pressure, hypoxemia, and hypercapnia; studies of sleep disordered breathing in patients with COPD during acute respiratory decompensation; studies of sleep disordered breathing in patients with acute cardiovascular decompensation; and studies of self-management strategies for treating obstructive sleep apnea. Education and Training A major component of the sleep center program is its role in providing expert education in sleep medicine and physiology to the Columbia Presbyterian Medical Center (CPMC) community of patients and providers. CPMC fellows, resident physicians, and medical students receive instruction in the interpretation of polysomnography, the diagnosis and treatment of sleep disorders, and the techniques of measurement and interpretation of the physiology of sleep and breathing, in the sleep laboratory. The center currently trains all pulmonary, allergy, and critical care fellows at Columbia University in sleep medicine. The center has contractual arrangements to formally train pulmonary fellows from other medical institutions including international fellows. All medical house staff at CPMC rotate through the sleep center during their ambulatory medicine block.

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