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Department of Medicine

 

 

Address:

Columbia University, College of Physicians & Surgeons

161 Fort Washington Avenue

Herbert Irving Pavilion-312
New York, NY 10032

 

Phone: 212-305-5346

lls2@columbia.edu

 

 

 

Larry L. Schulman, M.D.

Professor of Clinical Medicine, Division of Pulmonary, Allergy and Critical Care Medicine

 

 

Education and Training

1974      B.A., Cornell University

1978      M.D., State University of New York – Downstate

1978-79 Intern in Medicine, Columbia University, College of Physicians & Surgeons, New York, NY (Dr. Thomas Q. Morris)

1979-81 Resident in Medicine, Columbia University, College of Physicians & Surgeons, New York, NY (Dr. Thomas Q. Morris)

1981-82  Clinical Fellow, Mount Sinai School of Medicine, New York, NY (Dr. Alvin S. Teirstein)       

1982-83  Visiting Fellow, Columbia University, College of Physicians and Surgeons, New York, NY (Dr. Rejane Harvey)

1983-86 Parker B. Francis Research Fellow, Columbia University, College of Physicians & Surgeons, New York, NY (Dr. Yale Enson)

 

Academic Appointments

1983-84 Instructor in Clinical Medicine, Columbia University, College of Physicians and Surgeons, New York, NY

1984 -1996 Assistant Professor of Clinical Medicine, Columbia           University, College of Physicians and Surgeons, New York, NY

1996 -2002 Associate Professor of Clinical Medicine, Columbia           University, College of Physicians and Surgeons, New York, NY

2002 -present  Professor of Clinical Medicine, Columbia University, College of Physicians and Surgeons, New York, NY

 

Hospital Appointments

1984-1996 Assistant Attending Physician, The Presbyterian Hospital in the City of New York, New York, NY

1996-2002 Associate Attending Physician, The Presbyterian Hospital in the City of New York, New York, NY

2002-present  Attending Physician, The Presbyterian Hospital in the City of New York, New York, NY

1985-2001 Founder and Medical Director of Lung Transplant Service            

2002-present  Medical Director, Quality Assurance, The Presbyterian Hospital in the City of New York, New York, NY

2005-present  Medical Director, Quality Assurance, The Presbyterian Hospital Allen Pavilion, New York, NY

 

Teaching Experience:

1984-present       Abnormal Human Biology                                                                

1987-90              Introduction to the Patient                                                              

1984- present     Medical Preceptor                                                                

1995-present       Sciences Basic to the Practice of Medicine and Dentistry                

 

Professional Organizations and Societies

Fellow, American College of Chest Physicians

American Thoracic Society

American Medical Association

International Society for Heart and Lung Transplantation

American Society of Transplant Physicians

Trudeau Society

 

Committees:

American College of Chest Physicians, Practice Management Committee (1999 – 2002)

Columbia University, Department of Medicine, Executive Committee (2002-present)

New York-Presbyterian Hospital, Quality and Patient Safety Committee (2003-present)

New York-Presbyterian Hospital, Significant Events Committee (2003-present)

 

 

RECENT PUBLICATIONS

 

1.      Gougoutas CA, Austin JHM, Schulman LL.   Gastroparesis after lung transplantation: analysis of the gastric air bubble on chest radiographs.   J Thorac Imaging, 2000, 15:65-70.  

 

2.      Garfein ES, McGregor CC, Galantowicz ME, Schulman LL.   Deleterious effects of telescoped bronchial anastomosis in single and bilateral lung transplantation.   Ann Transplant 2000,5:5-11.   

 

3.      Schulman LL, Htun T, Staniloae C, McGregor C, Austin JHM.   Pulmonary nodules and masses after lung and heart-lung transplantation.   J Thorac Imaging 2000,15:173-179.   

 

4.      Schulman LL, Weinberg, AD,. McGregor CC, Galantowicz ME, Smith CR.   Influence of lung injury on early postoperative survival after lung transplantation.   Ann Transplant 2000, 5:20-25.

 

5.      Garfein ES, Ginsberg M, Gorenstein L, McGregor CC, Schulman LL.   Superiority of end-to-end telescoped bronchial anastomosis in single lung transplantation for pulmonary emphysema.   J Thorac Cardiovasc Surg, 2001 121:149-154.   

 

6.      Schulman LL, Weinberg AD, McGregor C, Suciu-Foca N, Itescu S.   Influence of donor and recipient HLA locus mismatching on development of obliterative bronchiolitis after lung transplantation.   Am J Respir Crit Care Med 2001, 163:437-442.  

 

7.      Imai K, Dalal SS, Chen ES, Downey R, Schulman LL, Ginsburg M, D'Armiento J.   Human collagenase (matrix metalloproteinase-1) expression in the lungs of patients with emphysema.   Am J Respir Crit Care Med 2001, 163:786-791.  

 

8.      Schulman LL. Anandarangam T, Leibowitz DW, DiTullio, MR, McGregor CC, Galantowicz ME, Homma S.   Four-year prospective study of pulmonary venous thrombosis after lung transplantation.   J Am Soc Echocardiogr 2001, 14:806-812.

 

9.      Talbot SM, Taub RN, Keohan ML, Edwards N, Galantowicz ME, Schulman LL.   Combined heart and lung transplantation for unresectable primary cardiac sarcomas.   J Thorac Cardiovasc Surg, 2002, 124:1145-1148.  

 

10.  Imai K, Mercer BA, Schulman LL, Sonett JR, D'Armiento JM.  Correlation of lung surface area to apoptosis and proliferation in human emphysema.  Eur Respir J. 2005, 25(2):250-258.

 

 

Case Reports

1.      Schulman LL, Enson Y.   Diffusing capacity to predict arterial desaturation during exercise. (Letter)   N Engl J Med 1984, 311:376.

 

2.      Schulman LL.   Oxygen therapy in sickle cell anemia. (Letter)   N Engl J Med 1984, 311:1119.

 

3.      Schulman LL, Grimes M.   Metastatic Kaposi's sarcoma and bilateral chylothorax.   NY State J Med 1986. 86(4):205-206.

 

4.      Kaufman DG, Schulman LL, Nagler HM.   Cystic fibrosis presenting in a forty-five year old man with infertility.   J Urol 1986, 136:1081-1082.

 

5.      Schulman LL.   Cytomegalovirus Pneumonitis and lobar consolidation.   Chest 1987, 91(4):558-561.

 

6.      Schulman LL, Enson Y.   Nocardia Pneumonitis and the adult respiratory distress syndrome.   Am J Med Sci 1987, 293(5):315-319.

 

7.      Smiley RM, Navedo AT, Kirby T, Schulman LL.   Postoperative independent lung ventilation in a single-lung transplant recipient.   Anesthesiology 1991, 74:1144-1148.

 

8.      Schulman LL, Austin JHM.   Paratracheal radiolucency as a sign of tracheal disruption after heart-lung transplantation.   J Thoracic Imaging 1994, 9:123-125.

 

9.      Lederman C. Spitz JL, Scully B, Schulman LL, Della-Latta P, Weitzman I, Grossman M.   Mycobacterium haemophilum cellulitis in a heart transplant recipient.   J Am Acad Dermatol 1994; 30(5):804-806.

 

10.  Simsir A, Greenebaum E, Nuovo G, Schulman, LL.   Late fatal adenovirus pneumonitis in a lung transplant recipient.   Transplantation 1998, 65: 592-594.

 

11.  Watanabe M, Homma S, Schulman LL.   Fatal cerebral emboli in two recipients of lung transplants from one donor.   Transplantation 2003, 75:2157-2158.

 

 

Reviews, chapters and editorials

1.      Schulman LL.   Editorial: Quality of life after lung transplantation.   Chest 1995, 108:1489-1490.  

 

2.      Schulman LL.   Physiology of the transplanted lung (PP. 519-526) in: Primer on Transplantation.   Norman and Suki, editors, 1998, Slack Inc., Chelsea MI.  

 

3.      Schulman LL.   Editorial: Perioperative mortality and primary graft failure after lung transplantation.   Chest 1998, 114: 7-8.  

 

4.      Schulman LL.   Lung transplantation for Chronic Pulmonary Disease in: Clinics in Chest Medicine, 2000, 21:894-866.

 

5.      Schulman LL.   Lung Transplantation Update.   J Respir Dis 2000, 21:634-642.  

 

6.      Schulman LL.   Quality of life Issues in transplantation: thoracic organ transplantation.   Transplant Proc 2001, 33:1878-1879.  

 

7.      Schulman LL.   Physiology of the transplanted lung (PP. 674-680) in: Primer on Transplantation, Second Edition.   Norman and Turka, editors, 2001, American Society of Transplantation, Mt. Laurel, NJ.  

 

8.      Schulman LL.   Relationship between lung transplantation and LVRS in the treatment of advanced for pulmonary emphysema (PP. 237-264) in: Lung Volume Reduction Surgery for End-stage Emphysema. Argenziano editors, 2002, Humana Press Inc.  

 

9.      Schulman LL, Estenne M.   Effects of transplantation on lung and exercise physiology (PP. 220-244) in: Lung Transplantation. Boe, Estenne, Weder editors, 2003, European Respiratory Society, Sheffield UK.  

 

Abstracts

1.      Schulman LL. Enson Y.  Effects of hyperoxia and prostaglandin inhibition on pulmonary vascular resistance in canine granulomatous lung disease.  Am Rev Resp Dis 1984, 129(4):331.

 

2.      Schulman LL, Wood JA, Enson Y.  Prostanoids attenuate hypoxic vasoconstriction in canine granulomatous lung disease.  Clin Res 1984, 32(20):530.

 

3.      Schulman LL, Enson Y.  Determinants of shunt flow in canine granulomatous lung disease.  Physiologist 1984,  27(4):280.

 

4.      Schulman LL, Enson Y.  Oxygen enrichment induces pulmonary vasodilation after prostaglandin inhibition.  Am Rev Resp Dis 1985, 131(4):424.

 

5.      Lennon PF, Schulman LL, Enson Y.  Effect of air trapping on single breath diffusing capacity measurement.  Am Rev Resp Dis 1985, 131(4):61.

 

6.      Schulman LL, Enson Y.  Hyperoxia induces pulmonary vasodilation after cyclooxygenase inhibition.  Chest 1985, 88:465.

 

7.      Schulman LL, Lennon PF, Ratner SJ, Enson Y.  Vasodilator prostanoids regulate perfusion in acute oleic acid pulmonary edema.  Am Rev Resp Dis 1986, 133(4):160.

 

8.      Schulman LL, McCullough P, Lennon PF, Wood JA, Enson Y.  Pulmonary vascular resistance in emphysema.  Am Rev Resp Dis 1986, 133(4):223.

 

9.      Schulman LL, Smith CR, Drusin R, Rose EA, Enson Y.  Respiratory complications of cardiac transplantation.   J Heart Transplantation 1987, 5(5)387.

 

10.  Schulman LL, Smith CR, Drusin R, Rose EA, Enson Y, Reemtsma K.  Utility of airway endoscopy in the diagnosis of respiratory complications of cardiac transplantation.  Am Rev Respir Dis 1987, 135(4):110.

 

11.  Schulman LL, Smith CR, Drusin R, Rose EA, Enson Y, Reemtsma K.  Respiratory complications of cardiac transplantation.  Am Rev Respir Dis 1987, 135(4):43.

 

12.  Schulman LL, Smith CR, Drusin R, Rose EA, Enson, Y, Reemtsma K.  Cytomegalovirus Pneumonitis after cardiac transplantation.  Chest 1987, 92(2):55S.

 

13.  Austin JHM, Mastrobattista JD, Schulman LL.  Pulmonary infection in cardiac transplant recipients clinical-radiologic correlations.  Am Rev Respir Dis 1988, 137(4):245.

 

14.  Kirby TK, Smith C, Schenkel F, Vargo R, Barr M, Rice TW, McCarthy PM, Schulman LL, Mehta A.  Changing indications  for single lung transplantation.  Chest 1991, 100(2):464S.

 

15.  Kirby TK, Smith C, Schenkel F, Vargo R, Barr M, Rice TW, McCarthy PM, Schulman LL, Mehta A.  Immediate postoperative  steroids and normal bronchial healing in lung transplantation.  Chest 1991, 100:64S.

 

16.  Auteri JS, Michler RE, Schulman LL, McGregor C, Schenkel FA, Smith C.  Steroids and bronchial healing in lung transplantation: early clinical experience.  J Heart Lung Transplant 1992, 11:216.

 

17.  Shreeniwas R, Marboe C, McGregor C, Zanger D, Schulman LL.  Adhesion molecules in pulmonary allograft rejection.  Am Rev Respir Dis 1993, 147(4):A197.

 

18.  Berkowitz N, Schulman LL, McGregor C, Markowitz D.  Gastroparesis after lung transplantation:  Potential role in postoperative complications.  Am Rev Respir Dis 1993, 147(4):A605.

 

19.  Schulman LL, Ho E, Reed E, Marboe C, Suciu-Foca N.  Association between infiltrating lymphocyte growth and acute rejection in lung allograft recipients.  Am Rev Respir Dis 1994; 149(4): A1095.

 

20.  Schulman LL, McGregor C, Ho E, Reed E, Suciu-Foca N.  The role of anti-HLA antibodies in lung transplantation  Am Rev Respir Dis 1994; 149(4): A1096.

 

21.  Leibowitz D, Michler R, Smith C, Ginsburg M, Schulman L, McGregor C, Weslow R, DiTullio M, Homma S.  Complications involving the pulmonary venous anastomoses after lung transplantation:  a prospective transesophageal echocardiographic study.  J Heart Lung Transplantation 1994, 13:S29.

 

22.  Leibowitz D, Caputo A, Shapiro G, Schulman L, McGregor C, Ginsburg M, Michler R, Smith C, DiTullio M, Homma S.  Yield of coronary angiography in smokers undergoing evaluation for lung transplantation.  J. Heart Lung Transplantation 1994, 13:S86.

 

23.  Leibowitz D, Michler R, Smith C, Ginsburg M, Schulman L, McGregor C, Weslow R, DiTullio M, Homma S.  Importance of imaging the pulmonary veins after lung transplantation : a prospective transesophageal echocardiographic study.   J Am Coll Cardiol 1994, 24(2):357A.  

 

24.  Leibowitz D, Caputo A, ,Shapiro G, Schulman L, McGregor C, Ginsburg M, Michler R, Smith C, DiTullio M, Homma S.  Is routine use of coronary angiography justified for smokers undergoing lung transplantation evaluation?  J Am Coll Cardiol 1994, 24(2):435A.  

 

25.  Shane E, Schulman LL, McGregor C, Addesso V, Staron RB, Factor-Litvak P.  Skeletal status in patients with end-stage lung disease may increase risk of fracture after transplantation.  J Heart Lung Transplantation 1995; 14: S38.

 

26.  Shreeniwas R, Austin JHM, Berkmen Y, McGregor C, Schulman LL.  Opportunistic bronchopulmonary infections after lung transplantation: clinical and radiologic correlations.  Am J Respir Crit Care Med 1995; 151(4): A90.

 

27.  Shreeniwas R, Schulman LL, McGregor C, Ginsburg ME, Michler RE, Oz MC, Smith CR.  Relation between anastomotic technique and airway complications after lung transplantation.  Am J Respir Crit Care Med 1995; 151(4): A90.

 

28.  Shane E, Schulman LL, McGregor C, Donovan D, Addesso V, Staron RB, Factor-Litvak P.  Osteoporosis in patients  awaiting lung transplantation.  Am J Respir Crit Care Med 1995; 151(4): A91.

 

29.  Gougoutas CA, Austin JHM, Schulman LL.  Gastroparesis after lung transplantation: analysis of the gastric air bubble on chest radiographs.  Am J Respir Crit Care Med 1995; 151(4): A82.

 

30.  Shreeniwas R, Austin JHM, Berkmen Y, McGregor C, Schulman LL.   Radiographic patterns of CMV pneumonitis after lung transplantation.   Chest 1995, 108: 205S.  

 

31.  DiMango AM, Schulman LL, McGregor C, Simonelli PF.   Expression of transforming growth factor (TGF) -b1 RNA by bronchoalveolar lavage cells obtained from lung transplant recipients.   Chest 1995, 108: 126S.  

 

32.  Leibowitz DW, Schulman LL, DiTullio MR, McGregor CC, Ellison JP, Michler RE, Smith CR, Homma S.  Variability of right ventricular functional recovery following lung transplantation.   Chest 1995, 108: 170S.  

 

33.  DiMango AM, Schulman LL, McGregor C, Tester W, Simonelli PF.   Transforming growth factor (TGF) -b1 RNA by bronchoalveolar lavage cells obtained from lung transplant recipients is increased during episodes of acute rejection.   Am J Respir Crit Care Med 1996, 153(4): A151.  

 

34.  Schulman LL, McGregor C, Ho E, Michler R, Ginsburg M Suciu-Foca N.  Immunologic evaluation of lung allograft recipients.  Am J Respir Crit Care Med 1996; 153(4): A154.

 

35.  O’Hair DP, Schulman LL, McGregor C, Simonelli PF, Jellen P, Ginsburg M.   Contralateral lung volume reduction surgery after single lung transplantation for emphysema.   Chest 1996, 110: 174S.  

 

36.  O’Hair DP, Umana JP, McGregor C, Ginsburg M, Smith CR, Galantowicz ME, Schulman LL.   Lung transplantation using mycophenolate mofetil.   Chest 1996, 110: 220S.  

 

37.  Anadarangam T, Schulman L, Leibowitz D, McGregor C, Michler R, Ginsburg M, Homma S, Gerow-Smith R, Jorgensen B, Smith CR.   Pulmonary venous anastomotic complications after lung transplantation. Chest 1996, 110: 225S.  

 

38.  Fisher PE, Igwebe TE, McGregor CC, Schulman LL.   Histopathologic predictors of obliterative bronchiolitis (OB) versus freedom from OB after lung transplantation.   J Heart Lung Transplant 1997, 16: 46.  

 

39.  O’Hair DP, Schulman LL, McGregor C, Simonelli PF, Jellen P, Ginsburg ME. Lung volume reduction surgery following single lung transplantation for emphysema. J Heart Lung Transplant 1997, 16: 54.  

 

40.  Schulman LL, Burke E, Weinberg AD, Tung TC, Smith CR, Suciu-Foca N, Galantowicz ME, Itescu S.   Donor and recipient matches at HLA-DR and HLA-B loci are risk factors for high grade cellular rejections in lung transplantation.   J Heart Lung Transplant 1997, 16: 68.  

 

41.  Itescu S, Weinberg AD, Burke E, Bosworth B, Smith CR, Suciu-Foca N, Galantowicz ME, Schulman LL.   Risk factors for early onset obliterative bronchiolitis after lung transplantation: influence of HLA-DR4 type.   J Heart Lung Transplant 1997, 16: 69.  

 

42.  O’Hair DP, Umana JP, McGregor C, Ginsburg ME, Smith CR, Schulman LL, Galantowicz ME.   Lung transplantation using mycophenolate mofetil.   J Heart Lung Transplant 1997, 16: 75.  

 

43.  Schulman LL, Burke E, Weinberg AD, Tung TC, Suciu-Foca N, Itescu S.   Influence of HLA-DR locus on high grade cellular rejection and early onset obliterative bronchiolitis after lung transplantation.   Am J Respir Crit Care Med 1997, 155(4): A272.  

 

44.  Schulman LL, Burke E, Weinberg AD, Tung TC, Suciu-Foca N, Itescu S.   Influence of HLA-DR locus on high grade cellular rejection and early onset obliterative bronchiolitis after lung transplantation.   Am J Respir Crit Care Med 1997, 155(4): A272.  

 

45.  Bjekic G, DiMango AM, Schulman LL, McGregor C, Tester W, Liu ZL, Simonelli PF.   Platelet-derived growth factor (PDGF) RNA detection is highly correlated with Transforming growth factor (TGF) -b1 RNA in bronchoalveolar lavage cells obtained from lung transplant recipients.   Am J Respir Crit Care Med 1997, 155(4): A272.  

 

46.  Chen ES, Dalal SS, Downey R, Ginsberg ME, Schulman LL, Chada K, D’Armiento J.   Collagenase (MMP) overexpression in human emphysema.   Am J Respir Crit Care Med 1997, 155(4): A588.  

 

47.  Chong DH, Hembree W, McGregor C, Simonelli PF, Galantowicz ME, Schulman LL.   Gonadal dysfunction in men with advanced lung disease.   Am J Respir Crit Care Med 1997, 155(4): A717.  

 

48.  Igwebe T, McGregor C, Garfeind E, Goldstein D, Schulman LL.   Early allograft function after lung transplantation.   Chest 1997, 112(3): 119S.  

 

49.  Keshavjee SH, Davis RD, Zamora MR, Schulman LL, Levin J, Ryan U, Patterson GA.   Inhibition of complement in human lung transplant reperfusion injury: a multicenter clinical trial.   J Heart Lung Transplant 1998, 17: 43.  

 

50.  Schulman LL, Anadarangam T, Leibowitz D, Nahar T, M. DiTullio, McGregor C, Smith CR, Homma S.   A prospective study of pulmonary venous thrombosis after lung transplantation.   Am J Respir Crit Care Med 1998, 157:523.  

 

51.  Shane E, Papadopoulos A, Staron RB, Addesso V, Donovan D, McGregor C, Schulman LL.   A prospective study of bone loss and fracture after lung transplantation. Am J Respir Crit Care Med 1998, 157:525.

 

52.  Garfein ES, Milliken EE, McGregor C, Galantowicz ME, Schulman LL.   Deleterious effects of telescoped anastomosis in single and double lung transplantation.   Chest 1998, 114(4): 283S.  

 

53.  Schulman LL, Htun T, Staniloae C, McGregor C, Austin JHM.   Pulmonary nodules and masses after lung transplantation.   Am J Respir Crit Care Med 1999, 159:A537.  

 

54.  Bade MA, Rajasinghe HA, Beniaminowitz A, Galantowicz ME, Schulman LL, Sinha P, Goldstein DJ, Rose EA, Edwards NM.   Orthotopic heart and heart-lung transplantation for locally advanced cardiac tumors.   J Heart Lung Transplant 2000, 19: 95.

 

 

MANUSCRIPTS IN PREPARATION

 

1.      Schulman LL, Chong DH, McGregor C, Hembree W .   Gonadal dysfunction in men with advanced lung disease.   in preparation.  

 

2.      Walter K, Austin JHM, Mancini D, Edwards N, Schulman LL.   Screening Chest CT in preoperative cardiac transplant patients.   in preparation.  

 

 

 

 

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