Division of Pulmonary,
Allergy and Critical Care Medicine
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Mailing Address: College
of Physicians & Surgeons Phone: (212)
305-8625 Clinical Office Address:
College
of Physicians & Surgeons Phone: (212)
304-7166 |
Robert Charles Basner, M.D. Associate
Professor of Clinical Medicine, Division of Pulmonary Allergy and Critical
Care Medicine Clinical Interests: Sleep
Disordered Breathing; Abnormal Pulmonary Physiology Awake and During Sleep,
Non-invasive Ventilation. Research Interests: Cardiopulmonary
Interactions Awake and During sleep; Cardiovascular Complications of Sleep
Deprivation; Pathophysiology, Cardiovascular
Complications, and Treatment of Obstructive Sleep Apnea Syndrome;
Non-Invasive Ventilation in
Amyotrophic Lateral Sclerosis (ALS); Pulmonary Function Testing in Emphysema
and ALS Education and Positions: M.D., Intern and Resident in
Internal Medicine, Beth Israel Hospital/Harvard Medical School, Boston MA,
1983-1986 Clinical and Research Fellow,
Respiratory Division, Brigham and Women's Hospital/Harvard Medical School, Instructor in Medicine, Assistant Professor of
Medicine, Associate Professor of
Medicine, University of Illinois College of Medicine, Chicago, IL 1995-1999 Diplomate:
American Board of Internal Medicine; American Board of Internal
Medicine, Sub-specialty in Pulmonary Diseases, Sub-specialty in Critical
Care; American Board of Sleep Medicine Honors: Magna Cum Laude, City Sidney Zolot
Music Award, City Alpha Omega Alpha, Merck Award for Outstanding
Scholastic Achievement, Fellow, Central Society for
Clinical Research, 1992 Fellow, American Sleep
Disorders Association, 1992 National Institutes of Health,
National Heart, Lung, and Blood Institute, Sleep Academic Career Award, 1997 Research Career Enhancement
Award, American Physiological Society, 2001 Will Rogers Institute, ALS
Association Grant, 2007. Other Memberships: American Federation for
Clinical Research, American Physiological Society, American Thoracic Society Publications: Reiffel, J.A., P. Wang, R. Basner, J.T. Bigger, Jr., F. Livelli, Jr., K. Ferrick, J. Gliklich, and J. Zimmerman. Electrophysiologic
testing in patients with recurrent syncope: are results predicted by prior
ambulatory monitoring? Am. Heart J. 110:1146-1153, 1985. Reiffel, J.A., J.T. Bigger, Jr., K. Ferrick, F.D. Livelli, J. Gliklich, P.Wang, and R. Basner. Sinus node echoes and
concealed concealed conduction: additional sinus
node phenomena confirmed in man by direct sinus node electrography.
J. Electrocardiology 18:259-266, 1985. Basner, R. C., P.M. Simon, R.M. Schwartzstein, S.E. Weinberger, and
J.W. Weiss. Breathing route influences upper airway muscle activity
in awake normal adults. J. Appl. Physiol.
66:1766-1771, 1989. Basner, R. C., J. Ringler, S. Berkowitz, R.M. Schwartzstein, S.E.
Weinberger, D. Sparrow, and J.W. Weiss. Effect of inspired air
temperature on genioglossus activity during nose
breathing in awake humans. J. Appl. Physiol.
69:1098-1103, 1990. Ringler, J., R.C. Basner, R. Shannon, R. Schwartzstein, H. Manning, S.E. Weinberger, and J.W.
Weiss. Hypoxemia alone does not explain blood pressure elevations after
obstructive apneas. J. Appl. Physiol. 69:2143-2148, 1990. Basner, R.C., J. Ringler, R.M. Schwartzstein, S.E. Weinberger, and J.W. Weiss. Phasic electromyographic
activity of the genioglossus increases in normals during slow-wave sleep. Respir.
Physiol. 83:189-200, 1991. Simon,
P.M., R.C. Basner,
S.E. Weinberger, V. Fencl, J.W. Weiss, and R.M. Schwartzstein. Oral mucosal stimulation modulates
intensity of breathlessness induced in normal subjects. Am. Rev. Respir. Dis. 144:419-422, 1991. Manning,
H.L., R. Basner, J.
Ringler, C. Rand, V. Fencl,
S.E. Weinberger, J.W. Weiss, and R.M. Schwartzstein.
Effect of chest wall vibration on breathlessness in normal subjects. J. Appl.
Physiol. 71:118-124, 1991. Garpestad, E., R.C. Basner, J. Ringler, J. Lilly, R. Schwartstein,
S.E. Weinberger, and J.W. Weiss. Phenylephrine
induced hypertension acutely decreases genioglossus
EMG activity in awake humans. J. Appl. Physiol. 72:110-115, 1992. Basner, R.C., J. Ringler, E. Garpestad, R.M. Schwartzstein,
D. Sparrow, J. Lilly, S.E. Weinberger, and J.W. Weiss. Upper airway
anesthesia delays arousal from airway occlusion induced during human non-REM
sleep. J. Appl. Physiol. 73:642-648, 1992. Basner, R.C. Disorders of the pulmonary vasculature. In: May,
H.L. (ed.), Emergency Medicine (2nd edition). Sparrow,
D., G.T. O'Connor, R.C. Basner,
B. Rosner, and S.T. Weiss. Predictors of the new
onset of wheezing among middle-aged and older men: The normative aging study.
Am. Rev. Respir. Dis. 147:367-371, 1993. Carlson,
D.M., D.W. Carley, E. Önal,
M. Lopata, and R.C. Basner. Acoustically induced cortical arousal
increases phasic pharyngeal muscle and
diaphragmatic EMG in NREM sleep. J. Appl. Physiol
76:1553-1559, 1994. Ringler, J., Basner, R.C., E. Önal, D.W. Carley, E.J. Stepanski, and M. Lopata. Effect of induced transient arousal on
obstructive apnea duration. J. Appl. Physiol
78:1469-1476, 1995. Stepanski, E., M. Faber, F. Zorick, R.
Basner, and T. Roth. Sleep disorders in patients on chronic
ambulatory peritoneal dialysis. J. Am Soc. Nephrology 6:192-197, 1995. Carlson,
D.M., E. Önal, D.W. Carley,
M. Lopata, and R.C. Basner. Palatal muscle electromyogram
activity in obstructive sleep apnea. Am. J. Respir.
Crit. Care Med. 152:1022-1027, 1995. Carley, D.W., R. Applebaum,
R.C. Basner, E. Önal, and M. Lopata.
Respiratory and electrocortical responses to
acoustic stimulation. Sleep 19: S189-192, 1996. Basner, R.C. Treatment of obstructive sleep apnea. In: Leff, A.R. (ed), Pulmonary Pharmacology and Therapeutics.
McGraw-Hill.; pages 1053-1058, 1996. Carley, D.W., R. Applebaum,
R.C. Basner, E. Önal, and M. Lopata.
Respiratory and arousal responses to acoustic stimulation. Chest
112:1567-1571, 1997. Crisostomo, I., A. Zayyad,
D.W. Carley, J. Abubaker,
E. Önal, E.J. Stepanski,
M. Lopata, and R.C. Basner. Chemo- and baroresponses
differ in African-Americans and Caucasians in sleep. J. Appl. Physiol.
85:1413-1420, 1998. Basner, R.C., and E. Önal.
Disordered breathing during sleep. In: Cherniack,
N.S., I. Homma, and M.D. Altose (eds.),
Rehabilitation of the Patient With Respiratory Disease: McGraw-Hill,
pp.169-184, 1998. Stepanski, E., A. Zayyad,
C. Nigro, M. Lopata, and R. Basner. Sleep-disordered
breathing in a predominantly African-American pediatric population. Journal
of Sleep Research 8:65-70, 1999. Rahaghi, F., and R.C. Basner. Delayed diagnosis of
obstructive sleep apnea: Don't ask, don't tell. Sleep and Breathing
3:119-124, 1999. Basner, R.C. Recognizing sleep-disordered breathing in the
21st century. J. Respir Dis
22: 657-670, 2001. Jelic , S., M.N. Bartels, J.H. Mateika,
P Ngai, R.
E. DeMeersman,
and R. C. Basner. Arterial
stiffness increases during obstructive sleep apneas. Sleep 25: 850-855, 2002.
Bartels, M.N., S. Jelic, P. Ngai, R.C. Basner,
and R.E. DeMeersman. High frequency modulation of
heart rate variability during exercise in patients with chronic obstructive
pulmonary disease. Chest 124:863-869, 2003. Bartels, M.N., S. Jelic, R.C. Basner, P. Ngai,
J.M. Gonzalez, and R.E. DeMeersman. Supplemental
oxygen increases arterial stiffness in chronic obstructive pulmonary disease.
Respir Med 98: 84-89, 2004. Bell-McGinty, S., C. Habeck, H.J.
Hilton, B. Rakitin, N. Scarmeas, E. Zarahn, J.
Flynn, R. DeLaPaz, R. Basner, and Y. Stern.
Identification and differential vulnerability of a neural network in
sleep deprivation. Cerebral Cortex 14:496-502, 2004. Merritt, S.L., H.C. Schnyders,
M. Patel, R.C. Basner, and W.
O'Neill. Pupil staging and EEG measurement of sleepiness. International
Journal of
Psychophysiology 52:97-112, 2004. Gates, G.J, S. E. Mateika,
R. C. Basner, and J. H. Mateika. Baroreflex sensitivity in non-apneic snorers and controls before and after
nasal continuous positive airway pressure. Chest 126: 801-807, 2004. Bartels, M.N., S. Jelic, P. Ngai, G. Gates, D. Newandee,
S.S. Reisman, R.C.
Basner, and R.E. DeMeersman. The effect of
ventilation on spectral analysis of heart rate and blood pressure variability
during exercise. Respir Physiol
and Neurobiology 144:91-98, 2004. Zhong, X.,
H. J. Hilton, S. Jelic, Y.
Stern, M. N. Bartels,R. E. DeMeersman, and R. C. Basner . Increased sympathetic
and decreased parasympathetic cardiovascular modulation in normal humans with
acute sleep deprivation. .J. Appl Physiol 98: 2024-2032, 2005. Zhong, X.,
Y. Xiao, and R. C. Basner. Effects
of antihypertensives on arterial responses
associated with obstructive sleep apneas. Chin Med J 118:123-129, 2005. Bazil, C.W., J.
Battista, and R.C. Basner. Effects
of levetiracetam on sleep in normal volunteers.
Epilepsy and Behavior
7:539-542, 2005. Bazil, C.W., J. Battista, and R.C. Basner. Gabapentin
improves sleep in the presence of alcohol.
J Clin Sleep Med 1(3): 284-287, 2005. Lederer, D.J., C.E. Caplan-Shaw , M.K. O'Shea, J.S. Wilt, R.C. Basner, M.N. Bartels, J.R. Sonett, S.M. Arcasoy, and S.M. Kawut. Racial and ethnic
disparities in survival in lung transplant candidates with idiopathic
pulmonary fibrosis. Am J of Transplantation 6;
398-403, 2006. Padeletti M, A. Henriquez, D.M. Mancini, and R.C. Basner. Persistence
of Cheyne-Stokes breathing following left ventricular
assist device implantation in patients with acutely decompensated
end stage heart failure. J Heart Lung Transplant 26: 742-744, 2007. Barr, R.G., S. Mesia-Vela, J. H. M. Austin, R. C. Basner, B.M. Keller, A. Reeves, D. Shimbo,
and L. Stevenson. Impaired flow-mediated dilatation is associated with low
pulmonary function and emphysema in ex- smokers: the Emphysema and Cancer
Action Project (EMCAP) Study. Am J Respir Crit Care Med
176:1200-1207, 2007. Luber, B.,
A.D. Stanford, P.Bulow, T. Nguyen, B.C. Rakitin, C. Habeck, R. Basner, Y. Stern, and S.H. Lisanby. Remediation of sleep-deprivation induced working
memory impairment with fMRI-guided transcranial magnetic stimulation. Cerebral Cortex doi:10:1093/cercor/bhm231; 2008. Barr, R.G., K. J. Stemple, S. Mesia-Vela, R.C. Basner, S. Derk, P. Henneberger, D. K. Milton, and B. Taveras..
Reproducibility and validity of a handheld spirometer. Respiratory Care 53: 2008. Jelic, S., M. Padeletti, C. Higgins, S. M. Kawut, H. D. Onat, R. C. Basner,
P. C. Colombo, P. Factor, and T. H. LeJemtel..
Inflammation, oxidative stress and repair capacity of the vascular
endothelium in obstructive sleep apnea. Circulation Apr 29;117(17):2270-2278,
2008. Padeletti M, A.
M. Mooney, P. Green, R.C. Basner,
and D.M. Mancini. Sleep disordered breathing in patients with acutely decompensated heart failure. Sleep Medicine 2008,
doi:10.1016/j.sleep.2008.03.010. Basner, R.C. Book
Review, Restless Nights. Understanding
Snoring and Sleep Apnea. Basner, R.C. Book Review, Sleep Deprivation. Clinical Issues, Pharmacology, and Sleep Loss
Effects. Kushida, C.A., ed. N Engl. J. Med.
352: 2145-2146, 2005. Basner, R.C. Shift Work Sleep Disorder: The Glass Is More
Than Half Empty. Editorial, Basner, R.C..
"Augmentation" of augmentation index studies in obstructive sleep
apnea. Letter to the Editor, Sleep
28:1170, 2005. Basner, R.C. Continuous Positive Airway Pressure for
Obstructive Sleep Apnea. Clinical Therapeutics. N. Engl. J. Med. 2007;356:1751-1758. Basner, R.C. Obstructive sleep apnea/hypopnea syndrome. In:
Goldman, L. and Ausiello D (eds),
Cecil Textbook of Medicine, 23rd
edition, pp. 705-709, Elsevier Press, 2007. Atkeson, A., and R.C. Basner. Quality of life in sleep
apnea. In:J.C.
Verster,
S.R. Pandi-Perumal, D.L. Streiner
(eds), Sleep and Quality of Life in Medical Illness:
pp. 79-91, Humana Press, USA 2008. Sanders, M.H., and R.C.
Basner. The effect of sleep in patients with neuromuscular and chest wall
disorders. UpToDate. Basner,
R.C. Respiratory management. In: Mitsumoto,
H, ed. Amyotrophic Lateral Sclerosis: A
Guide for Patients and Families, 3rd edition. Demos Health,
Basner, R.C.
"Snow in The Wind's Wires." The Columbia Review, 2001, p.25.
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