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Francis Y. Lee, M.D.
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PUBLICATIONS:

  1. Seo, S.; Adelmir, A.; Minematsu, H.; and Lee, F. : ERK SIGNALING REGULATES M-CSF EXPRESSION INDUCED BY TITANIUM NANOPARTICLES IN MC3T3-E1 MURINE CALVARIAL PRE-OSTEOBLASTIC CELLS. Ann N Y Acad Sci, (In Press), 2007.
  2. Minematsu, H.; Seo, S.; Adelmir, A.; and Lee, F. : CALCINEURIN/NFATC1 AXIS REGULATES UHMWPE WEAR PARTICLE-INDUCED CYTOKINE EXPRESSION IN MACROPHAGES. Ann N Y Acad Sci, (In Press) 2007.
  3. Lowenstein, J. E.; Matsumoto, H.; Vitale, M. G.; Weidenbaum, M.; Gomez, J. A.; Lee, F. Y. ; Hyman, J. E.; and Roye, D. P., Jr.: Coronal and sagittal plane correction in adolescent idiopathic scoliosis: a comparison between all pedicle screw versus hybrid thoracic hook lumbar screw constructs. Spine, 32(4): 448-52, 2007 .
  4. Kim, D. W.; Seo, S. W.; Cho, S. K.; Chang, S. S.; Lee, H. W.; Lee, S. E.; Block, J. A.; Hei, T. K.; and Lee, F. Y. : Targeting of cell survival genes using small interfering RNAs (siRNAs) enhances radiosensitivity of Grade II chondrosarcoma cells. J Orthop Res, 25(6): 820-8, 2007 .
  5. Adelmir, A.; Kim, D.; and Lee, F. : Calcineurin/NFATc axis mediated fluid shear stress-induced COX-2 expression in human mesenchymal cells. Ann N Y Acad Sci, [Epub ahead of print], 2007.
  6. Vitale, M. A.; Choe, J. C.; Sesko, A. M.; Hyman, J. E.; Lee, F. Y. ; Roye, D. P., Jr.; and Vitale, M. G.: The effect of limb length discrepancy on health-related quality of life: is the '2 cm rule' appropriate? J Pediatr Orthop B, 15(1): 1-5, 2006 .
  7. Lee, F. Y. ; Sinicropi, S. M.; Lee, F. S.; Vitale, M. G.; Roye, D. P., Jr.; and Choi, I. H.: Treatment of congenital pseudarthrosis of the tibia with recombinant human bone morphogenetic protein-7 (rhBMP-7). A report of five cases. J Bone Joint Surg Am, 88(3): 627-33, 2006 .
  8. Kim, Y. S.; Bigliani, L. U.; Fujisawa, M.; Murakami, K.; Chang, S. S.; Lee, H. J.; Lee, F. Y. ; and Blaine, T. A.: Stromal cell-derived factor 1 (SDF-1, CXCL12) is increased in subacromial bursitis and downregulated by steroid and nonsteroidal anti-inflammatory agents. J Orthop Res, 24(8): 1756-64, 2006 .
  9. Kim, D. W. et al.: Mechanical loading differentially regulates membrane-bound and soluble RANKL availability in MC3T3-E1 cells. Ann N Y Acad Sci, 1068: 568-72, 2006 .
  10. Yu, J.; Chang, S. S.; Suratwala, S.; Chung, W. S.; Abdelmessieh, P.; Lee, H. J.; Yang, J.; and Lee, F. Y. : Zoledronate induces apoptosis in cells from fibro-cellular membrane of unicameral bone cyst (UBC). J Orthop Res, 23(5): 1004-12, 2005 .
  11. Yoon, A. J.; Parisien, M.; Feldman, F.; and Young-In Lee, F. : Extranodal Rosai-Dorfman disease of bone, subcutaneous tissue and paranasal sinus mucosa with a review of its pathogenesis. Skeletal Radiol, 34(10): 653-7, 2005 .
  12. Vitale, M. G.; Roye, E. A.; Choe, J. C.; Hyman, J. E.; Lee, F. Y. ; and Roye, D. P., Jr.: Assessment of health status in patients with cerebral palsy: what is the role of quality-of-life measures? J Pediatr Orthop, 25(6): 792-7, 2005 .
  13. Vitale, M. G.; Choe, J. C.; Vitale, M. A.; Lee, F. Y. ; Hyman, J. E.; and Roye, D. P., Jr.: Patient-based outcomes following clubfoot surgery: a 16-year follow-up study. J Pediatr Orthop, 25(4): 533-8, 2005 .
  14. Storer, S. K.; Vitale, M. G.; Hyman, J. E.; Lee, F. Y. ; Choe, J. C.; and Roye, D. P., Jr.: Correction of adolescent idiopathic scoliosis using thoracic pedicle screw fixation versus hook constructs. J Pediatr Orthop, 25(4): 415-9, 2005 .
  15. Liao, T. S. et al.: Recruitment of osteoclast precursors by stromal cell derived factor-1 (SDF-1) in giant cell tumor of bone. J Orthop Res, 23(1): 203-9, 2005 .
  16. Lee, F. Y. ; Schoeb, J. S.; Yu, J.; Christiansen, B. D.; and Dick, H. M.: Operative lengthening of the humerus: indications, benefits, and complications. J Pediatr Orthop, 25(5): 613-6, 2005 .
  17. Lee, F. Y. et al.: mu-Calpain regulates receptor activator of NF-kappaB ligand (RANKL)-supported osteoclastogenesis via NF-kappaB activation in RAW 264.7 cells. J Biol Chem, 280(33): 29929-36, 2005 .
  18. Blaine, T. A. et al.: The molecular pathophysiology of subacromial bursitis in rotator cuff disease. J Shoulder Elbow Surg, 14(1 Suppl S): 84S-89S, 2005 .
  19. Young-In Lee, F. ; Hornicek, F. J.; Dick, H. M.; and Mankin, H. J.: Synovial chondromatosis of the foot. Clin Orthop Relat Res, (423): 186-90, 2004 .
  20. Ugwonali, O. F.; Lomas, G.; Choe, J. C.; Hyman, J. E.; Lee, F. Y. ; Vitale, M. G.; and Roye, D. P., Jr.: Effect of bracing on the quality of life of adolescents with idiopathic scoliosis. Spine J, 4(3): 254-60, 2004 .
  21. Roposch, A.; Bhaskar, A. R.; Lee, F. ; Adedapo, S.; Mousny, M.; and Alman, B. A.: Orthopaedic manifestations of Brachmann-de Lange syndrome: a report of 34 patients. J Pediatr Orthop B, 13(2): 118-22, 2004 .
  22. Lee, F. Y. ; Yu, J.; Chang, S. S.; Fawwaz, R.; and Parisien, M. V.: Diagnostic value and limitations of fluorine-18 fluorodeoxyglucose positron emission tomography for cartilaginous tumors of bone. J Bone Joint Surg Am, 86-A(12): 2677-85, 2004 .
  23. Delloye, C.; Suratwala, S. J.; Cornu, O.; and Lee, F. Y. : Treatment of allograft nonunions with recombinant human bone morphogenetic proteins (rhBMP). Acta Orthop Belg, 70(6): 591-7, 2004 .
  24. Chang, S. S.; Suratwala, S. J.; Jung, K. M.; Doppelt, J. D.; Zhang, H. Z.; Blaine, T. A.; Kim, T. W.; Winchester, R. J.; and Lee, F. Y. : Bisphosphonates may reduce recurrence in giant cell tumor by inducing apoptosis. Clin Orthop Relat Res, (426): 103-9, 2004 .
  25. Vitale, M. G.; Choe, J. C.; Hwang, M. W.; Bauer, R. M.; Hyman, J. E.; Lee, F. Y. ; and Roye, D. P., Jr.: Use of ketorolac tromethamine in children undergoing scoliosis surgery. an analysis of complications. Spine J, 3(1): 55-62, 2003 .
  26. Lee, F. Y. , and Chapman, C. B.: In situ pinning of hip for stable slipped capital femoral epiphysis on a radiolucent operating table. J Pediatr Orthop, 23(1): 27-9, 2003 .
  27. Osgood, G. M.; Lee, F. Y. ; Parisien, M. V.; and Ruzal-Shapiro, C.: Magnetic resonance imaging depiction of tight iliotibial band in melorheostosis associated with severe external rotation deformity, limb shortening and patellar dislocation in planning surgical correction. Skeletal Radiol, 31(1): 49-52, 2002 .
  28. Lee, F. Y. ; Zawadsky, M.; Parisien, M.; Ho, M.; Murty, V. V.; Jayaraman, T.; and Dick, H. M.: Novel translocation (9;12)(q22;q24) in secondary chondrosarcoma arising from hereditary multiple exostosis. Cancer Genet Cytogenet, 132(1): 68-70, 2002 .
  29. Lee, F. Y. ; Storer, S.; Hazan, E. J.; Gebhardt, M. C.; and Mankin, H. J.: Repair of bone allograft fracture using bone morphogenetic protein-2. Clin Orthop Relat Res, (397): 119-26, 2002 .
  30. Patari, S. K.; Lee, F. Y. ; and Behrens, F. F.: Coronal split fracture of the proximal tibia epiphysis through a partially closed physis: a new fracture pattern. J Pediatr Orthop, 21(4): 451-5, 2001 .
  31. Lee, F. ; Keel, S. B.; Gebhardt, M. C.; and Rosenthal, D. I.: Intra-articular lipoma with osteochondroid metaplasia in the knee joint. Skeletal Radiol, 30(4): 230-3, 2001 .
  32. Ahmad, C. S., and Lee, F. Y. : An all-arthroscopic soft-tissue balancing technique for lateral patellar instability. Arthroscopy, 17(5): 555-7, 2001 .
  33. Ramappa, A. J.; Lee, F. Y. ; Tang, P.; Carlson, J. R.; Gebhardt, M. C.; and Mankin, H. J.: Chondroblastoma of bone. J Bone Joint Surg Am, 82-A(8): 1140-5, 2000 .
  34. Margau, R.; Babyn, P.; Cole, W.; Smith, C.; and Lee, F. : MR imaging of simple bone cysts in children: not so simple. Pediatr Radiol, 30(8): 551-7, 2000 .
  35. Lee, F. Y. ; Hazan, E. J.; Gebhardt, M. C.; and Mankin, H. J.: Experimental model for allograft incorporation and allograft fracture repair. J Orthop Res, 18(2): 303-6, 2000 .
  36. Lee, F. Y. ; Montgomery, M.; Hazan, E. J.; Keel, S. B.; Mankin, H. J.; and Kattapuram, S.: Recurrent giant-cell tumor presenting as a soft-tissue mass. A report of four cases. J Bone Joint Surg Am, 81(5): 703-7, 1999 .
  37. Lee, F. Y. ; Mankin, H. J.; Fondren, G.; Gebhardt, M. C.; Springfield, D. S.; Rosenberg, A. E.; and Jennings, L. C.: Chondrosarcoma of bone: an assessment of outcome. J Bone Joint Surg Am, 81(3): 326-38, 1999 .
  38. Lee, F. Y. ; Rho, J. Y.; Harten, R., Jr.; Parsons, J. R.; and Behrens, F. F.: Micromechanical properties of epiphyseal trabecular bone and primary spongiosa around the physis: an in situ nanoindentation study. J Pediatr Orthop, 18(5): 582-5, 1998 .
  39. Lee, F. Y. ; Hornicek, F. J.; Hazan, E. J.; Kloen, P.; Wolfe, M. A.; and Mankin, H. J.: Reconstruction of the shoulder joint using an acetabular allograft. A report of two cases. Clin Orthop Relat Res, (357): 116-21, 1998 .
  40. Lee, F. Y. ; Gebhardt, M. C.; Keel, S. B.; and Rosenthal, D. I.: A discrete soft tissue mass in the distal thigh of a 29-year-old man. Clin Orthop Relat Res, (357): 247-50, 255-6, 1998 .
  41. Lee, F. Y. ; Choi, Y. W.; Behrens, F. F.; DeFouw, D. O.; and Einhorn, T. A.: Programmed removal of chondrocytes during endochondral fracture healing. J Orthop Res, 16(1): 144-50, 1998 .
  42. Benevenia, J.; Lee, F. Y. ; Buechel, F.; and Parsons, J. R.: Pathologic supracondylar fracture due to osteolytic pseudotumor of knee following cementless total knee replacement. J Biomed Mater Res, 43(4): 473-7, 1998 .
  43. Harten, R. D., Jr.; Lee, F. Y. ; Zimmerman, M. C.; Hurowitz, E.; Arakal, R.; and Behrens, F. F.: Regional and temporal changes in the acoustic properties of fracture callus in secondary bone healing. J Orthop Res, 15(4): 570-6, 1997 .
  44. Seong, S. C.; Matsumura, T.; Lee, F. Y. ; Whelan, M. C.; Li, X. Q.; and Trippel, S. B.: Insulin-like growth factor I regulation of Swarm rat chondrosarcoma chondrocytes in culture. Exp Cell Res, 211(2): 238-44, 1994 .
  45. Kim, Y. M.; Lee, S. H.; Lee, F. Y. ; Koo, K. H.; and Cho, K. H.: Morphologic and biomechanical study of avascular necrosis of the femoral head. Orthopedics, 14(10): 1111-6, 1991 .

 

BOOKS AND CHAPTERS

 

  1. Carol Morris, Lee FY and Gebhardt MC: Benign Bone Tumors, Chapter, Operative Orthopaedic Surgery, Ed. Chapman M, Williams and Wilkins (2000).
  2. Lee FY and Lee HK: Basic science in musculoskeletal tumor, Chapter, Musculoskeletal Oncology, Ed. Lee HK, 1996, Korea.
  3. Hyman J, Lee FY , Roye DP: Orthopaedic Surgery, Chapter, Pediatric Secrets, Ed, 2002.
  4. Seo SW, Moon YL, Lee FY : Benign Cystic Lesions. Essentials of Orthopaedic Surgery, (In Preparation)
  5. Seo SW, F Remotti, Lee FY : Chondrosarcoma, Orthopaedic Knowledge Update, Musculoskeletal Oncology (In Press)