About COR

FY Lee
Francis Y. Lee, M.D., Ph.D.

The Center for Orthopaedic Research (COR) was established in 2003, by Dr. Louis U. Bigliani, chairman, Department of Orthopaedic Surgery to champion cutting edge molecular biomedical engineering and biomechanical research, provide stimulating laboratory environments for post-doctoral fellows, orthopaedic residents and students, and to advance novel concepts through translational studies that bridge basic science, research, and clinical practice. Our ultimate aspiration is to develop breakthrough therapies in patient diagnosis, treatment and outcome.

The Molecular Biomedical Engineering Laboratory program analyzes musculoskeletal disease processes and immunologic responses at molecular and cellular levels. Some of our current research examines cellular functions and interactions initiating pathologic changes in bone reformation, congenital pseudarthrosis of the tibia, and tumor-induced osteolysis. Theory is translated into practical application through studies involving animal models, a standard foundation for sound clinical investigation.

The Biomechanics Laboratory applies the principles of engineering mechanics processes and behaviors under various conditions to optimize the understanding of musculoskeletal form and function for the advancement of rehabilitation modalities, surgical techniques, and instrumentation research and development.

Funding awards from prestigious foundations have helped to validate the importance of our research. Funding agencies include the National Institutes of Health, the Department of Defense, the Orthopaedic Research Education Foundation, and the Orthopaedic Science and Research Foundation, established by Robert E. Carroll, Professor Emeritus, Department of Orthopaedic Surgery, Columbia University Medical Center.

Welcome to the Center for Orthopaedic Research!

Francis Y. Lee, M.D., Ph.D.
Director, Center for Orthopaedic Research

Robert Carroll & Jane Chace Carroll Laboratories Professor of Orthopaedic Surgery
Vice Chair for Research, Director of Research Laboratories