Grant # R21 NR010823
Title: Electronic Communication for Antimicrobial Management (ECAM)
PI: Leanne Currie, RN, DNSc, Assistant Professor of Nursing, Columbia University School of Nursing

The goal of this study is to improve the appropriate and judicious use of antibiotics in the neonatal intensive care unit by developing and testing an automated method to remind clinicians to stop or change inappropriate antibiotics. 

Grant # T90 NR010824
Title: Training in Interdisciplinary Research to Reduce Antimicrobial Resistance (TIRAR)
Program Co-Directors: Kristine Gebbie, RN, DrPH, Elizabeth Standish Gill Professor of Nursing, Columbia University School of Nursing and Aaron Mitchell, PhD, Harold S. Ginsberg Professor of Molecular Pathogenesis and Acting Chair, Department of Microbiology, College of Physicians & Surgeons of Columbia University

This training grant prepares pre- and post-doctoral scholars for participation and leadership in interdisciplinary research to reduce antimicrobial resistance by creating an interdisciplinary research curriculum; developing CIRAR pre- and postdoctoral training programs; implementing a faculty training program in interdisciplinary research; and  developing and maintaining programmatic self-evaluation and revision mechanisms.

Grant # R01 NR010822
Title: Distribution of the Costs of Antimicrobial Resistant Infections
PI: Sherry Glied, PhD, Professor and Chair, Department of Health Policy and Management, Mailman School of Public Health, Columbia University

The project will develop estimates of the distribution of the extra costs associated with antimicrobial resistance and assess how policies that change incentives could spur adoption of effective interventions. 

Thrasher Research Fund--New Researcher Award
Title: Persistence of Antibiotic Resistance Organisms in the Gastrointestinal Tract of Neonates: A Pilot Study
PI: Sameer J. Patel, MD, Clinical Fellow, Department of Pediatrics, Division of Infectious Diseases, Columbia University Medical Center
Mentor: Lisa Saiman, MD, MPH, Professor of Clinical Pediatrics, Department of Pediatrics, College of Physicians & Surgeons of Columbia University

The goal of this study is describe the rate of persistence of gastrointestinal antibiotic resistant organism (ARO) carriage in infants known to be colonized at discharge from the NICU to the community; determine risk factors for long term colonization (≥ 3 months); and to determine if AROs are transmitted between infants and mothers.

Grant # R01 CI000537, Applied Research in Antimicrobial Resistance: Studies of Susceptibility Testing on Gram-negative Multidrug Resistant Organisms
PI: Lisa Saiman, MD, MPH, Professor of Clinical Pediatrics, Department of Pediatrics, College of Physicians & Surgeons of Columbia University

The goals of this project are to: 1) determine strategies to improve the treatment of patients infected with MDR-GNB and thus improve clinical and microbiological outcomes of such infections, (2) assess which laboratory algorithms for in vitro antimicrobial susceptibility testing most closely correlate with improved outcomes for MDR-GNB infections, and (3) evaluate how healthcare professionals actually use in vitro susceptibility data to choose and modify treatment regimens for MDR-GNB infections.

Grant # R01 NR010107 Prevention of Nosocomial Infections and Cost-Effectiveness Analysis (P-NICE)
PI: Patricia W. Stone, RN, PhD, MPH, Associate Professor of Nursing, Columbia University School of Nursing

The aims of this study are to: 1) describe the level of infection control staffing and intensity of infection prevention and control interventions currently in place in intensive care units (ICU) across the nation; 2) determine associations between current infection control staffing and intensity of infection prevention and control interventions, and probability healthcare-associated infections and short term survival in elderly ICU patients; 3) estimate the long term outcomes attributable to healthcare-associated infections in elderly patients; and 4) determine the cost-effectiveness of effective infection control staffing and infection prevention and control interventions in ICU.

Visit the P-NICE Web Site

Supported by the
National Institute of Nursing Research/National Institutes of Health