AIMS
The Center for Interdisciplinary Research to Reduce Antimicrobial
Resistance (CIRAR) was originally funded in 2004 with a planning grant
from the National Center for Research Resources, NIH (Grant number:
P20 RR020616).
Since 2007, a total of 14 projects affiliated with CIRAR have been
externally funded. In 2007 and 2008, five projects
affiliated with CIRAR were funded by the National Institute of Nursing
Research, NIH and two were funded by the Centers for Disease Control
and Prevention; (Click here
to download the funding announcement). In 2009, four additional CIRAR-affiliated
projects have been funded: an AHRQ Conference Grant, an IICTR CaMPR
award funded by the NCRR, a 5-year R01 funded by the NIAID, and a
2-year RC1 Challenge Grant funded by the NCHMD. CIRAR continues to prepare biomedical researchers and others in interdisciplinary
research with a focus on the prevention and control of antimicrobial
resistance.
What Does CIRAR Do?
The overall mission of CIRAR is to reduce antimicrobial resistance
through innovative interdisciplinary research. CIRAR serves as an
umbrella coordinating center to foster and sustain a community of
interdisciplinary scholars engaged in such research.
In addition to the aims of specific CIRAR projects, the
Center SPECIFIC AIMS are to:
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1. |
Implement a new paradigm of interdisciplinary
research to reduce antimicrobial resistance. |
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2. |
Build and sustain a community of
interdisciplinary scholars who contribute to the body of
knowledge regarding the prevention of antimicrobial resistance. |
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3. |
Provide an infrastructure and coordination to
support interdisciplinary research teams. |
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4. |
Provide mentorship and support for investigators
and trainees for conducting interdisciplinary research. |
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5. |
Foster regular interaction with the broader
academic community, the public, media and policy makers
regarding interdisciplinary research and the global problem of
antimicrobial resistance. |
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6. |
Share research results and resources from CIRAR
investigations and disseminate widely among scientific and lay
communities through seminars, electronic media, etc. |
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7. |
Develop new
proposals to continue funded interdisciplinary research related
to reducing antimicrobial resistance. |
Researchers from all disciplines as well as trainees committed to
developing research skills congruent with the aims of CIRAR are
encouraged to become involved in the activities of the Center.
Activities include monthly symposia, interdisciplinary courses, and
training opportunities. CIRAR also provides infrastructure to
researchers committed to developing interdisciplinary research teams
and preparing grant proposals for funding. We encourage graduate
students to develop theses and dissertation projects in collaboration
with our funded, senior researchers and/or to seek consultation from
core staff for interdisciplinary projects related to the reduction of
antimicrobial resistance.
Affiliated funded projects at
Columbia University Medical Center under the rubric of CIRAR currently
include the following:
Projects Funded in 2009
RC1 MD004109, Appropriate Care of URI in Children
of Latino Immigrants: The ACURI Project
PI:
Melissa Stockwell,
MD, MPH, Assistant Professor of Clinical Pediatrics, College of
Physicians & Surgeons of Columbia University and Assistant Professor
of Population and Family Health, Mailman School of Public Health,
Columbia University
R01 AI082536, Risk Factors for Spread of
Staphylococcus aureus in Prisons
Co-PIs: Franklin D. Lowy, MD,
Professor of Medicine
and Pathology,
Division of Infectious Diseases,
College of Physicians & Surgeons of Columbia University
and Elaine Larson, RN, PhD,
Professor of Therapeutic and Pharmaceutical Research,
Columbia
University School of
Nursing
Improving Health Literacy Regarding URI
in Families in Home Visitation Programs
Co-PIs:
Melissa Stockwell,
MD, MPH, Assistant Professor of Clinical Pediatrics, College of
Physicians & Surgeons of Columbia University and Assistant Professor
of Population and Family Health, Mailman School of Public Health,
Columbia University; Marina Catallozzi, MD,
Assistant Professor of Clinical Pediatrics, College of Physicians &
Surgeons of Columbia University and Assistant
Professor of Population and Family Health, Mailman School of Public
Health, Columbia University; Elaine Larson, RN, PhD,
Professor of Therapeutic and Pharmaceutical Research, Columbia
University School of
Nursing and Professor of Epidemiology, Mailman School of Public Health,
Columbia University
R13 HS018099, CMS Changes in
Reimbursement for HAIs: Setting a Research Agenda
PI: Patricia W. Stone, RN, PhD, MPH, Associate Professor
of Nursing, Columbia University School of Nursing
Co-PIs:
Elaine Larson, RN, PhD,
Professor of Therapeutic and Pharmaceutical Research;
Sherry Glied, PhD,
Professor and
Chair,
Department of Health Policy and Management;
Lisa
Saiman, MD, MPH, Professor of Clinical Pediatrics, Department of
Pediatrics
Projects Funded in
2008
Improving Appropriate Use of
Antibiotics for URI in Children of Recently Immigrated Latinos
Co-PIs:
Elaine Larson, RN, PhD,
Professor of Therapeutic and Pharmaceutical Research, Columbia
University School of
Nursing and Professor of Epidemiology, Mailman School of Public Health,
Columbia University; Melissa Stockwell,
MD, MPH, Assistant Professor of Clinical Pediatrics, College of
Physicians & Surgeons of Columbia University and Assistant Professor
of Population and Family Health, Mailman School of Public Health,
Columbia University; Marina Catallozzi, MD,
Assistant Professor of Clinical Pediatrics, College of Physicians &
Surgeons of Columbia University and Assistant
Professor of Population and Family Health, Mailman School of Public
Health, Columbia University
Thrasher Research Fund--New Researcher Award,
Persistence of Antibiotic Resistance Organisms in the Gastrointestinal
Tract of Neonates: A Pilot Study
PI: Sameer J.
Patel, MD, Clinical Fellow, Department of Pediatrics, Division of
Infectious Diseases,
Columbia
University
Medical
Center;
Mentor:
Lisa
Saiman, MD, MPH, Professor of Clinical Pediatrics, Department of
Pediatrics,
College of
Physicians & Surgeons of
Columbia
University
R01 NR010821, Improving Antimicrobial
Prescribing Practices in the Neonatal Intensive Care Unit
PI: Lisa Saiman, MD, MPH, Department of Pediatrics, College of
Physicians & Surgeons of Columbia University
TS-1431 (5 U50 CD3000-860-21), Impact of
Automated Surveillance on MRSA Isolation
PI:
Elaine Larson, RN, PhD,
Professor of Therapeutic and Pharmaceutical Research, Columbia
University School of
Nursing and Professor of Epidemiology, Mailman School of Public Health,
Columbia University
Projects Funded in
2007
R01 CI000537,
Applied Research in Antimicrobial
Resistance: Studies of Susceptibility Testing on Gram-negative
Multidrug Resistant Organisms
PI: Lisa Saiman, MD, MPH, Department of Pediatrics, College of
Physicians & Surgeons of Columbia University
T90 NR010824, Training in Interdisciplinary Research to
Reduce Antimicrobial Resistance (TIRAR)
Program Co-Directors:
Elaine Larson, RN, PhD,
Professor of Therapeutic and
Pharmaceutical Research, Columbia University School of Nursing and
Professor of Epidemiology, Mailman School of Public Health, Columbia
University;
Richard Kessin, PhD,
Professor
of Pathology and Cell Biology, College of Physicians & Surgeons of
Columbia University
R01 NR010822,
Distribution of the Costs of Antimicrobial
Resistant Infections
PI:
Elaine Larson, RN, PhD,
Professor of Therapeutic and
Pharmaceutical Research, Columbia University School of Nursing and
Professor of Epidemiology, Mailman School of Public Health, Columbia
University
R21 NR010823,
Electronic Communication for Antimicrobial
Management (ECAM)
PI: Leanne
Currie, RN, DNSc, Columbia University School of Nursing
R01 NR010107 Prevention of Nosocomial Infections
and Cost-Effectiveness Analysis (P-NICE)
PI: Patricia W. Stone, RN, PhD, MPH, Columbia University School of
Nursing
Visit the P-NICE Web Site
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