department of neurology  
 
 
  The Neurological Institute of New York || 710 West 168th Street, New York, NY 10032-3784 || Telephone: 212-305-2700  
 
 
 

NEUROSCIENCE RESEARCH AT COLUMBIA




MOTOR NEURON CENTER FOR BIOLOGY & DISEASE



RESEARCH


» Aging, Memory & Dementia
» Clinical Neurophysiology
» Cognitive Neuroscience
» Epilepsy
» Huntington Disease
» Mitochondrial Biology & Disease
» Motor Neuron Center for Biology & Disease
» Multiple Sclerosis
» Neural Stem Cells (opens in a new window)
» Neurobiology & Behavior
» Neurocritical Care/NICU
» Neuro-Oncology
» Neuropathy Research Center
» Parkinson Disease & Other Movement Disorders
» Pediatric Neurology
» Sergievsky Center; Neuroepidemiology
» Sleep
» Stroke
» Systems Neurobiology
» Taub Institute for Alzheimer Disease Research (opens in a new window)
» Research Support » Columbia MDA/ALS Research Center
» Columbia Motor Neuron Center

Hiroshi Mitsumoto, Director


The Center provides a multidisciplinary team approach for patients with ALS and their families. Comprehensive services include access to medical and psychosocial management, innovative therapeutic clinical trials, basic and clinical research, and expertise in palliative and biomedical care.

Petra Kaufmann


Muscular dystrophies, mitochondrial myopathies, other genetic diseases of muscle



THE H. HOUSTON MERRITT CENTER FOR NEUROMUSCULAR AND MITOCHONDRIAL DISORDERS

Molecular Biochemistry Laboratory



» Laboratory of Molecular Neurogenetics

Salvatore Dimauro


Biochemical and DNA investigations of human metabolic myopathies, including disorders of glycogen metabolism, lipid metabolism, and mitochondrial function.



Molecular Genetics Laboratories



Eric A. Schon


Molecular genetic studies of neuromuscular disorders. Current work includes analysis of respiratory chain genes (cytochrome c oxidase), mutations of mitochondrial DNA in human disease, and in vitro gene therapy.

Michio Hirano


Molecular biology of neuromuscular disorders. Positional cloning techniques applied to autosomal disorders affecting the mitochondrial genome. Investigations of mutations of mitochondrial DNA in human cardiomyopathies.

Eduardo Bonilla


Research involving the ultrastructure of membrane systems in normal and diseased human muscle. Procedures utilized involve transmission electron microscopy, immunocytochenustry, and in situ hybridization.



Tissue Culture Laboratory



Mercy Davidson


Morphological, biochemical, molecular genetic and electrophysiological analyses of mitochondrial encephalomyopathies using transmitochondrial cybrids, skeletal myoblasts, cardiomyocytes, and neuronal cells. Studies of tissue-specific effects of mutations associated with these diseases on normal development and function; and cell culture models for devising potential therapeutic strategies.



Muscle and Nerve Pathology Laboratory



Arthur P. Hays


Morphologic studies of diabetic and other neuropathies and motor neuron diseases.





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Aging, Memory & Dementia | Clinical Neurophysiology | Cognitive Neuroscience | Epilepsy | Huntington Disease | Mitochondrial Biology & Disease | Motor Neuron Center | Movement Disorders & Parkinson Disease | Multiple Sclerosis | Neural Stem Cells | Neurobiology & Behavior | Neurocritical Care/NICU | Neuro-Oncology | Neuropathy | Pediatric Neurology | Sergievsky Center & Neuroepidemiology | Stroke | Tabu Institute for Alzheimer Disease Research | Research Support
© 1997 The Neurological Institute of New York Center | 710 W 168th St, New York, NY 10032
Department of Neurology | Columbia University Medical Center | Last updated: September 10, 2009 | Comments