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NEUROSCIENCE RESEARCH AT COLUMBIAAGING, MEMORY AND DEMENTIA» Memory Disorders » Taub Institute for Research in Alzheimer Disease RESEARCH» Aging, Memory & Dementia » Clinical Neurophysiology » Cognitive Neuroscience » Epilepsy » Huntington Disease » Mitochondrial Biology & Disease » Motor Neuron Center for Biology & Disease » Multiple Sclerosis » Neural Stem Cells (opens in a new window) » Neurobiology & Behavior » Neurocritical Care/NICU » Neuro-Oncology » Neuropathy Research Center » Parkinson Disease & Other Movement Disorders » Pediatric Neurology » Sergievsky Center; Neuroepidemiology » Sleep » Stroke » Systems Neurobiology » Taub Institute for Alzheimer Disease Research (opens in a new window) » Research Support This group provides in-patient consultation services for patients with cognitive and behavioral disorders and staffs the Memory Disorders Clinic at the Psychiatric Institute. Residents are encouraged to elect rotations on this service. Research interests in behavioral disorders and dementia primarily focus on degenerative diseases such as Parkinson disease, Alzheimer disease, Huntington disease, and stroke. Neurologic, psychiatric and neuropsychologic functions are assessed. Current projects include studies of dementia in Parkinson disease, use of brain imaging in dementia, clinical trials, and epidemiology of Alzheimer disease and related disorders; natural history of HIV; cognitive performance in children with complex metabolic disorders. Aging and dementia rounds are held weekly at Columbia University Medical Center and monthly at Harlem Hospital Center. The research activities of the Division of Aging and Dementia are integrated closely with those of the Sergievsky Center, and all divisional faculty hold appointments in the Sergievsky Center. Karen S. Marder, DirectorInvestigations of genetic influences in families of probands with early-onset compared to late-onset Parkinson disease. Multicenter investigation of risk factors for the development of dementia in HIV. Clinical trials of new therapeutic agents in Huntington disease. Longitudinal study of subjects at risk for developing Huntington disease. Karen L. BellDevelopment of new clinical treatments for Alzheimer disease. Currently conducting research for the prevention of Alzheimer disease in individuals with mild cognitive impairment. Other research interests include understanding barriers that minorities face in receiving clinical care for dementia and cognitive loss, and developing mechanisms to recruit minorities into clinical research. Sandra Bell-McGintyClinical neuropsychology. Assessment of memory and behavior dysfunction, and evaluations for Alzheimer's disease and other dementia disorders. Elise CaccappoloClinical neuropsychology. Assessment of memory and behavior dysfunction, and evaluations for Alzheimer's disease and other dementia disorders. Lucien CôtéEpidemiology and genetics of Parkinson's disease. Studies of depression and dementia in Parkinson's disease. Lawrence S. HonigDr. Honig performs both basic and clinical research involving various aspects of Alzheimer disease, dementia and cognitive dysfunction. His laboratory research focusses on biomarkers in neurodegenerative disease including studies of gene expression in Lewy Body Disease, frontotemporal dementias, and Alzheimer disease, as well as work on genetic and epigenetic markers, the latter involving role of telomeres in biological aging. His clinical research includes both NIH funded research and pharmaceutical company funded clinical trials. He is the director of the Clinical Core of the NIA/NIH-funded Alzheimer Disease Research Center (ADRC) at Columbia University. He is the principal site investigator in a number of ongoing clinical drug trials aimed at Alzheimer disease, as well as in several clinical trials involving molecular neuroimaging. Jennifer ManlyEpidemiology and genetics of Parkinson's disease. Studies of depression and dementia in Parkinson's disease. Richard MayeuxDirector, G.H. Sergievsky Center and Co-Director, Taub Institute for Alzheimer Disease. Epidemiology and genetics of Alzheimer disease and Parkinson disease. (see Sergievsky Center) Nikolaos ScarmeasDr. Scarmeas has developed a special interest in the contribution of diet in AD risk. Recent literature on the effect of individual dietary elements is conflicting. He is investigating the effect of composite dietary patterns (such as the Mediterranean Diet) in AD risk. Scott SmallCorrelations of memory and changes in the hippocampal formation using functional magnetic resonance imaging in normal aging and in Alzheimer disease. Parallel studies in transgenic mice. Yaakov SternDr. Stern is using cognitive experimental and fMRI neuroimaging approaches to understand why some people are more susceptible to aging and disease pathology than others. |
 About Us | Our Doctors | Education | Research | Patients | Neuroscience | Directions || Sitemap Aging, Memory & Dementia | Clinical Neurophysiology | Cognitive Neuroscience | Epilepsy | Huntington Disease | Mitochondrial Biology & Disease | Motor Neuron Center | Movement Disorders & Parkinson Disease | Multiple Sclerosis | Neural Stem Cells | Neurobiology & Behavior | Neurocritical Care/NICU | Neuro-Oncology | Neuropathy | Pediatric Neurology | Sergievsky Center & Neuroepidemiology | Stroke | Tabu Institute for Alzheimer Disease Research | Research Support © 1997 The Neurological Institute of New York Center | 710 W 168th St, New York, NY 10032 Department of Neurology | Columbia University Medical Center | Last updated: September 10, 2009 | Comments |