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NEUROSCIENCE RESEARCH AT COLUMBIACOMPREHENSIVE EPILEPSY CENTERRESEARCH» Aging, Memory & Dementia » Clinical Neurophysiology » Cognitive Neuroscience » Epilepsy » Huntington Disease » Mitochondrial Biology & Disease » Motor Neuron Center for Biology & Disease » Multiple Sclerosis » Neural Stem Cells (opens in a new window) » Neurobiology & Behavior » Neurocritical Care/NICU » Neuro-Oncology » Neuropathy Research Center » Parkinson Disease & Other Movement Disorders » Pediatric Neurology » Sergievsky Center; Neuroepidemiology » Sleep » Stroke » Systems Neurobiology » Taub Institute for Alzheimer Disease Research (opens in a new window) » Research Support » Comprehensive Epilepsy Center Clinical Epilepsy ResearchCarl W. Bazil, Director» Columbia University Sleep Disorders Center Investigational drug trials; clinical pharmacology of antiepileptic drugs; sleep and epilepsy relationships; role of melatonin; outcomes of epilepsy surgery. Hyunmi ChoiDecision analysis. Patient preference assessment. Development of patient decision aid. Outcomes in intractable epilepsy. Derek J Chong, MD MScMolecular causes of drug-resistance in epilepsy. Nuclear Imaging in epilepsy. Clinical trials in epilepsy. Cellular injury from seizures. Predictors of good outcome following epilepsy surgery. Ronald Emerson, Catherine SchevonElectrophysiology of epileptic brain, signal processing of EEG recordings, and application to seizure localization and prediction; physiological basis of electroencephalography (EEG); electrophysiology-based techniques for functional mapping in children and adults. Marla J. HambergerPre and postoperative language and memory in epilepsy; new approaches to assess word finding; cortical stimulation language mapping, naming studies using fMRI; language and memory during intracarotid amobarbital testing. Lawrence J. HirschContinuous EEG monitoring in the critically ill; status epilepticus; nonconvulsive seizures; EEG, scalp and intracranial; anti-epileptic drugs; brain stimulation for epilepsy; sudden death in epilepsy; cardiac effects of seizures; epilepsy surgery. Steven C. KarceskiNew approaches to the surgical treatment of extratemporal localization-related epilepsies. Treatment options and decision making. Comparative value of different antiepileptic drug regimens. Alison PackStudies of the effects of epilepsy and antiepileptic drugs on bone metabolism. Neuroendocrine and reproductive aspects of epilepsy; human sexuality; women's issues related to epilepsy. Anil Mendiratta; Stanley ResorPregnancy and epilepsy; juvenile myoclonic epilepsy; non-surgical treatment of epilepsy.  NeuroepidemiologyW. Allen HauserNeuroepidemiology of seizures and epilepsy with specific interests in identifying and quantitating risk factors for seizure occurrence, the prognosis of seizures and epilepsy, and the consequences of head trauma. Ruth OttmanFamily and genetic studies of epilepsy and ALS dementia. Identification of gene defects in relation to seizure/epilepsy phenotypes and seizure susceptibility. Dale HesdorfferNeuroepidemiology of seizure disorders and consequences of severe head injury. Association between MRI-detected brain abnormalities and development among children with febrile seizures, prognosis for status epilepticus, and risk factors for newly diagnosed epilepsy. Impact of the acute management of severe brain injury on outcome (in collaboration with the Brain Trauma Foundation). Laboratory ResearchGuy M. McKhann, IIRole of astrocytes in epilepsy; glia-neuron interactions. Helen ScharfmanTranslational neuroscience is the main interest of the laboratory. Current projects include examining the role of Brain derived neurotrophic factor (BDNF) in seizures and epilepsy using animal models of the disease; abnormal neurogenesis in neurological disorders; looking at the effects of the hormones estrogen and testosterone on excitability of brain regions; and looking at the way water balance, controlled by water channels (aquaporins) in glia (support cells in the brain), regulate the response to traumatic brain injury and seizures. Melodie WinawerFamily and genetic studies of epilepsy; problems in phenotype definition; linkage analysis and delineation of human epilepsy susceptibility genes. |
About Us | Our Doctors | Education | Research | Patients | Neuroscience | Directions || Sitemap Aging, Memory & Dementia | Clinical Neurophysiology | Cognitive Neuroscience | Epilepsy | Huntington Disease | Mitochondrial Biology & Disease | Motor Neuron Center | Movement Disorders & Parkinson Disease | Multiple Sclerosis | Neural Stem Cells | Neurobiology & Behavior | Neurocritical Care/NICU | Neuro-Oncology | Neuropathy | Pediatric Neurology | Sergievsky Center & Neuroepidemiology | Stroke | Tabu Institute for Alzheimer Disease Research | Research Support © 1997 The Neurological Institute of New York Center | 710 W 168th St, New York, NY 10032 Department of Neurology | Columbia University Medical Center | Last updated: September 11, 2009 | Comments |