| Ira
Tabas, MD, PhD
Vice-Chairman of Research, Department of Medicine,
Columbia University
Professor of Medicine and Anatomy & Cell Biology
(in Physiology and Cellular Biophysics)
Columbia University College of Physicians and
Surgeons
Attending Physician of Medicine
Columbia University Medical Center
New York, New York
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Education/History
Dr. Tabas received his medical degree and his
doctorate in biochemistry from Washington University
in St. Louis, Missouri. His doctoral work, conducted
in the laboratory of Dr. Stuart Kornfeld, was
in the area of oligosaccharide processing during
glycoprotein biosynthesis. Subsequently, he completed
an internship and residency in internal medicine
and a fellowship in endocrinology and metabolism
at Columbia University Medical Center in New York
City. During that period, Dr. Tabas also conducted
a postdoctoral fellowship in the laboratory of
Dr. Alan Tall in the Department of Medicine at
Columbia University. It was during this fellowship
that Dr. Tabas became interested in the cell biology
of atherosclerosis.
Professional Society Affiliations
Dr. Tabas is a member of the American Society
of Biochemists and Molecular Biologists, the American
Association for the Advancement of Science, the
American Society for Cell Biology, the American
Society for Clinical Investigation, the American
Association of Physicians, and the Arteriosclerosis
Council of the American Heart Association.
Publications/Editorial Experience
Dr. Tabas has lectured worldwide on the role
of macrophages in atherosclerosis, and he has
published numerous articles on cholesterol metabolism.
His research has been published in various peer-reviewed
journals, including Nature Cell Biology, Proceedings
of the National Academy of Science USA, Journal
of Cell Biology, Journal of Biological Chemistry,
Current Opinions in Lipidology, and Arteriosclerosis,
Thrombosis, and Vascular Biology. He has served
on the editorial board of the Journal of Biological
Chemistry, and he is currently Deputy Editor of
the Journal of Clinical Investigation.
Award/Honors
Dr. Tabas has been the recipient of the American
Heart Association Established Investigator Award,
the Columbia University Doctor Harold and Golden
Lamport Research Award, and the American Heart
Association/ATVB Council Special Recognition Award.
Current Position/Responsibilities
In addition to his position as Professor of
Medicine and Anatomy & Cell Biology at Columbia
University, Dr. Tabas is Attending Physician of
Medicine at Columbia-Presbyterian Medical Center.
His current research focuses on intracellular
cholesterol metabolism in macrophages as it pertains
to atherosclerosis, with emphasis on macrophage-lipoprotein
interactions and lipoprotein uptake mechanisms;
atherogenic lipoprotein modifications, particularly
aggregation; intracellular cholesterol trafficking
and esterification; and mechanisms of cholesterol-induced
cytotoxicity and apoptosis.
last updated: May 6, 2005
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