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The Neuroendocrine Unit

Columbia University College of Physicians & Surgeons
Columbia-Presbyterian Medical Center

Harkness Pavilion 970
180 Fort Washington Avenue
New York, NY 10032

 Consultations can be arranged by calling (212) 305-2254.


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Index


Introduction

The Neuroendocrine Unit provides a multidisciplinary evaluation of patients with pituitary and hypothalamic disorders. The Unit accepts referrals for the evaluation and treatment of patients with prolactinomas, Cushing's disease, acromegaly, nonfunctioning pituitary tumors, hypopituitarism, and other pituitary and hypothalamic disorders. Patients can be referred from their physician or be self-referred. A neurosurgeon and radiologist work closely with the Neuroendocrine Unit team of Endocrinologists to develop a diagnostic and treatment plan. Weekly multidisciplinary rounds are held to discuss the care of patients referred to the Neuroendocrine Unit. The Neuroendocrine Unit Endocrinologists are experienced in the use of standard and investigational therapies for the treatment of hormone secreting pituitary tumors and a number of clinical research protocols are ongoing.


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Attendings Staff

Endocrinology

Neurosurgery

Neuroradiology

Pediatric Endocrinology


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Consultation Services

The Neuroendocrine Unit staff offers consultations, second opinions and ongoing management of disorders affecting pituitary and hypothalamic function including hormone secreting and non-secreting pituitary tumors as well as parasellar tumors. The Endocrinologist's evaluation is coordinated with results of detailed hormone testing and radiological studies as well as with the input of the Neurosurgery and Radiology staff.
 
 

Areas of special expertise:

Prolactinomas, Cushing's disease, acromegaly, non-functioning pituitary tumors.
 
 

Prolactinomas and hyperprolactinemia:

Differential diagnosis and therapy.
 
 

Cushing's syndrome:

Differential diagnosis of Cushing's syndrome (Ectopic ACTH syndrome, adrenal Cushing's and pituitary Cushing's), CRH stimulation testing and petrosal sinus sampling with CRH administration.
 
 

Acromegaly:

Treatment with octreotide, experimental protocol for cabergoline treatment of acromegaly, pre-operative work-up and post-operative evaluation of cure with highly sensitive GH and IGF-I measurements and glucose tolerance testing for GH suppression.

Clinical trials with pegvisomant (Somavert) therapy of Acromegaly: Patients being treated with Pegvisomant may also be eligible for free evaluation of body composition and heart structure and function before and during pegvisomant therapy.
 
 

Hypopituitarism:

Evaluation and treatment of adrenal, thyroid, GH and gonadal steroid deficiencies and diabetes insipidus.
 
 

Growth Hormone Deficiency:

Testing for GH deficiency; conventional GH therapy and therapy with an investigational long acting GH therapy administered as weekly injections.
 
 

Parasellar tumors:

Endocrinologic evaluation of parasellar tumors and non-pituitary causes of hypopituitarism.
 
 

Obesity:

Medical management of obesity, with a particular focus on hypothalamic obesity (weight gain due to brain tumor or injury). Clinical research studies on hypothalamic obesity, weight loss, body composition and insulin sensitivity.
 
 


Physicians wishing to refer a patient are welcome to discuss the referral with one of the Endocrinologists and should contact the Unit Coordinator regarding the referral at:
(212) 305-2254.


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Acromegaly Patient Support Group

For further information contact the Neuroendocrine Unit at:(212) 305-2254,
or Ms Chris Sucorowski at (201) 614-0764


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Neuroendocrine Clinical Conference

A weekly interdisciplinary conference attended by endocrinologists, pediatric endocrinologists, neurosurgeons and neuroradiologists. Cases referred to the Neuroendocrine Unit are discussed and a team approach to the diagnosis and management of these cases is taken. Physicians are welcome to attend and present cases. Interested physicians should contact the Unit Coordinator for details. 
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R. Sundeen
Last updated 11/04