Title: Phase II study of oral Temozolomide
for Soft Tissue Sarcoma
Unresectable, recurrent or metastatic disease.
No more than one prior chemotherapy regimen.
Prior Dacarbazine is permitted.
Prior surgery and/or radiation therapy allowed.
This outpatient treatment will be administered orally,
twice a day for 5 days per week during a twenty-eight day cycle.
Title: Phase II Study of CPT 11 in Previously
Treated Advanced Sarcoma.
Soft tissue sarcoma distantly metastatic, unresectable locally
advanced or recurrent disease.
Received one but not more than two prior chemotherapy regimens.
Outpatient intravenous chemotherapy.
Title: Phase II Study of Cardiac Transplantation
for Primary Cardiac Sarcomas.
Trial is under development at the present
Patients must have biopsy proven primary cardiac sarcoma, with
no evidence of metastatic disease. Patients will be evaluated
by both the medical oncologist and transplant team. In most cases
patients will be treated with three courses of chemotherapy prior
Title: Phase II Study in Collaboration with
the Southwest Oncology Group of Gemcitabine in Advanced Soft Tissue
Soft tissue sarcoma unresectable primary or metastatic
Patients must have received no prior gemcitabine.
Prior adjuvant chemotherapy so long as relapse has not occurred
within 6 months of the last dose of adjuvant chemotherapy.
Bone Marrow Transplant
Title: Phase II Study of high Dose Chemotherapy
in Inoperable or
Inoperable or Metastatic Sarcoma Evaluation by a Columbia University
Bone marrow Transplantation Unit Attending.
High dose Chemotherapy Followed by bone Marrow or Stem Cell Transplantation.
Treatment will be via intravenous infusion weekly as an outpatient.