Columbia University Medical Center Donald F. Klein, M.D., D.Sc.

Articles



  1. Whittier JR, Klein DF, Levine G, Weiss, D.  Mepazine (Pacatal):  Clinical trial with placebo control and psychological study.  Psychopharmacologia 1960; 1: 280-287.

  2. Whittier JR, Korenyi C, Klein DF, Foley W.  Prevention of degenerative disease:  A controlled study of anticoagulant prophylaxis.  J Chronic Dis 1961; 14: 202-212.

  3. Blumberg AG & Klein DF.  Severe papilledema associated with drug therapy.  Am J Psychiatry 1961; 118: 168-170.

  4. Pollack M, Karp E, Krauthamer G, Klein D, Fink M.  Neuropsychologic response patterns of some psychotropic drugs.  Neuropsychopharmacology  1961: 2: 381-384.

  5. Kramer JC, Klein DF & Fink M.  Withdrawal symptoms following discontinuation of imipramine therapy. Am J Psychiatry 1961; 118: 549-550.

  6. Klein DF & Fink M.  Psychiatric reaction patterns to imipramine.  Am J Psychiatry 1962; 119: 432-438.

  7. Klein DF & Fink M.  Behavioral reaction patterns with phenothiazines.  Arch Gen Psychiatry 1962; 7: 449-459.

  8. Kramer JC, Klein D, Fink M.  Imipramine as an adjunct to phenothiazine therapy.  Compr Psychiatry 1962;3: 377-380.

  9. Klein DF & Fink M.  Multiple item factors as change measures in psychopharmacology.  Psychopharmacologia 1963; 4: 43-52.

  10. Blumberg AG, Klein D, Pollack M.  Age related changes in blood pressure with chlorpromazine and imipramine. Excerpta Medica International Congress Series #57.  1963.  Sixth International Congress of Gerontology.

  11. Belmont I, Pollack M, Willner A, Klein DF, Fink M.  The effects of imipramine and chlorpromazine on perceptual analytic ability, perceptual responsivity and memory as revealed in Rorschach response.  J Nerv Ment Dis 1963; 137: 42-50.

  12. Gittelman R, Klein DF, Pollack M.  Effects of psychotropic drugs on long-term adjustment: A review. Psychopharmacologia 1964; 5: 317-338.

  13. Blumberg AG, Klein D, Pollack M.  Effects of chlorpromazine and imipramine on systolic blood pressure in psychiatric patients: Relationships to age, diagnosis and initial blood pressure.  J Psychiatry Res 1964; 2: 51-60.

  14. Belmont I, Birch HG, Klein DF, Pollack M.  Perceptual evidence of CNS dysfunction in schizophrenia.  Arch Gen Psychiatry 1964; 10: 395-408.

  15. Klein DF.  Management problems at Hillside Hospital 1960 and 1963.  J Hillside Hosp 1964; 13: 79-94.

  16. Klein DF.  Behavioral effects of imipramine and phenothiazines:  Implications for a psychiatric pathogenetic theory and theory of drug action.  Recent Adv Biol Psychiatry; 1964; 7: 273-287.

  17. Pollack M, Klein DF, Willner A, Blumberg AG, Fink M.  Imipramine-induced behavioral disorganization in schizophrenic patients:  Physiological and psychological correlates.  Recent Adv Biol Psychiatry 1964; 7: 53-61.

  18. Fink M, Pollack M, Klein DF, Blumberg AG, Belmont I, Karp E, Kramer JC, Willner A.  Comparative studies of chlorpromazine and imipramine (I): Drug discriminating patterns.  Neuropsychopharmacology 1964; 3: 370-372.

  19. Pollack M, Karp E, Belmont I, Willner A, Klein DF, Fink M.  Comparative studies of chlorpromazine and imipramine (II): Psychological performance profiles.  Neuropsychopharmacology 1964; 3: 374-376.

  20. Klein DF.  Visual hallucinations with imipramine.  Am J Psychiatry 1965; 121: 911-914.

  21. Fink M, Klein DF. Kramer JC.  Clinical efficacy of chlorpromazine-procyclidine combination, imipramine and placebo in depressive disorders.  Psychopharmacologia 1965; 7: 27-36.

  22. Burnett LL & Klein DF.  A guide for the psychiatric case study.  J Hillside Hosp 1965; 14: 54-68.

  23. Blumberg AG & Klein DF.  Methoxy-catecholamine excretion and the mecholyl test.  J Psychiatric Res 1965; 3: 239-254.

  24. Levenstein S, Pollack M, Klein DF.  Follow-up study of formerly hospitalized psychiatric patients:  Procedural considerations in data collection.  J Hillside Hospital 1966; 15(3-4): 152-164.

  25. Klein DF.  Chlorpromazine-procyclidine combination, imipramine and placebo in depressive disorders.  Can Psychiatric Assoc J 1966; 11: Sl46-S149.

  26. Levenstein S, Klein DF, Pollack M.  Follow-up study of formerly hospitalized voluntary psychiatric patients:  The first two years.  Am J Psychiatry 1966; 122: 1102-1109.

  27. Kennard MA, Pollack M, Klein DF.  The EEG qualities in a group of young adult hospitalized psychiatric patients.  Recent Adv Biol Psychiatry 1966; 8: 277-282.

  28. Blumberg AG & Klein DF.  Age, base blood pressure, diagnosis, and mecholyl test response.  Psychosom Med 1966;28: 789-794.

  29. Blumberg AG & Klein DF.  Psychotropic drugs, mecholyl test and outcome.  Excerpta Medica International Series 1966; 129: 1212-1216.

  30. Klein DF.  Diagnostic prediction of psychotropic drug effect:  Global outcome.  Excerpta Medica International Series 1966; 129: 736-740.

  31. Pollack M, Levenstein S, Klein DF.  A three year post-hospital follow-up of psychiatric patients:  First hospitalization in adolescence vs. adulthood.  Int J Child Psychiatry 1966; 33: 224-225.

  32. Klein DF.  Dilantin screening study in hospitalized psychiatric patients.  18th International Congress of Psychology 1966; 75-82.

  33. Klein DF & Cleary TA.  Platonic true scores and error in psychiatric rating scales.  Psychol Bull 1967; 68: 77-80.

  34. Klein DF.  Importance of psychiatric diagnosis in prediction of clinical drug effects.  Arch Gen Psychiatry 1967; 16: 118-126.

  35. Klein DF & Greenberg IM.  Behavioral effects of diphenylhydantoin in severe psychiatric disorders.  Am J Psychiatry 1967; 124: 847-849.

  36. Klein DF.  Treatment of phobias characterized by separation anxiety.  International Drug Therapy Newsletter 1967; 2: 16.

  37. Quitkin FM & Klein DF.  Follow-up of treatment failure:  Psychosis and character disorder.  Am J Psychiatry 1967; 124: 499-505.

  38. Klein DF.  Discussion of psychotropic effect of diphenyl-hydantoin (DPH).  Int J Neuropsychiatry 1967; (3) Suppl 2: S63.

  39. Pollack M, Levenstein S, Klein DF.  A three-year posthospital follow-up of adolescent and adult schizophrenics.  Am J Orthopsychiatry 1968; 38: 94-109.

  40. Blumberg AG & Klein DF.  Psychiatric diagnosis, activation and radioactive iodine uptake.  Arch Gen Psychiatry 1968; 18: 601-611.

  41. Rosen B, Klein DF, Levenstein S, Shahinian SP.  Social competence and posthospital outcome.  Arch Gen Psychiatry 1968; 19: 165-170.

  42. Klein DF, Honigfeld G, Feldman S.  Prediction of drug effect by diagnostic decision tree.  Dis Nerv Syst 1968; 29 Suppl: 159-187.

  43. Klein DF.  Psychiatric diagnosis and a typology of clinical drug effects.  Psychopharmacologia 1968; 13: 359-386.

  44. Gittelman-Klein R & Klein DF.  Marital status as a prognostic indicator in schizophrenia.  J Nerv Ment Dis 1968; 147: 289-296.

  45. Feldman S, Klein DF, Honigfeld G.  A comparison of successive screening and discriminant function techniques in medical taxonomy.  Biometrics 1969; 25: 725-734.

  46. Gittelman-Klein R & Klein DF.  Premorbid asocial adjustment and prognosis in schizophrenia.  J Psychiatric Res 1969; 7: 35-53.

  47. Quitkin FM & Klein DF.  Two behavioral syndromes in young adults related to possible minimal brain dysfunction.  J Psychiatric Res 1969; 7: 131-142.

  48. Rosen B, Klein DF, Levenstein S, Shahinian SP.  Social competence and posthospital outcome among schizophrenic and non-schizophrenic psychiatric patients.  J Abnorm Psychol 1969; 74: 401-404.

  49. Honigfeld G, Klein DF, Feldman S.  Prediction of psychopharmacologic effect in man:  Development and validation of a computerized diagnostic decision tree.  Comput Biomed Res 1969; 2: 350-361.

  50. Pollack M, Woerner MG, Goldberg P, Klein DF.  Siblings of schizophrenic and non-schizophrenic psychiatric patients:  Psychopathology and gender concordance.  Arch Gen Psychiatry 1969; 20: 652-658.

  51. Blumberg AG & Klein DF.  Chlorpromazine-procyclidine and imipramine:  Effects on thyroid function in psychiatric patients.  Clin Pharmacol Ther 1969; 10: 350-354.

  52. Mendel JC & Klein DF.  Anxiety attacks with subsequent agoraphobia.  Compr Psychiatry 1969; 10: 190-195.

  53. Rabiner CJ & Klein DF.  Imipramine treatment of school phobia.  Compr Psychiatry 1969; 10: 387-390.

  54. Klein DF & Cleary TA.  Platonic true scores:  Further comment.  Psychol Bull 1969; 71(4): 278-280.

  55. Rosen B, Klein DF, Gittelman-Klein R.  Sex differences in the relationship between premorbid asociality and posthospital outcome.  J Nerv Ment Dis 1969; 149(5): 415-420.

  56. Klein DF.  The prospective study of bereavement.  Arch Foundation of Thanatology 1969; 1: 13.

  57. Pollack M, Jaffe R, Woerner MG, Klein DF.  Fourteen- and six-per-second positive spikes in adolescent and young adult psychiatric patients and their siblings.  Proceedings of the American Psychological Association 1969.

  58. Klein DF.  Drugs and schizophrenia:  Critical evaluations.  Int J Psychiatry 1969; 8: 734-739.

  59. Mendel JC & Klein DF.  Anxiety attacks with subsequent agoraphobia.  Compr Psychiatry  1969; 10: 190-195.

  60. Rabiner CJ & Klein DF.  Imipramine treatment of school phobia.  Compr Psychiatry 1969; 10: 387-390.

  61. Glick ID, Hauptman B, Klein DF.  Pseudo-pregnancy treatment of periodic psychiatric illness:  A pilot study.  Psychiatr Quarterly 1970; 44: 1-5.

  62. Cohen M & Klein DF.  Drug abuse in a young psychiatric population.  Am J Orthopsychiatry 1970; 40(3): 448-455.

  63. Cohen M, Klein DF, Struve F.  Relationship between electroencephalographic and sociometric variables among psychiatric patients.  Am J Psychiatry 1970; 127(1): 137-141.

  64. Gittelman-Klein R & Klein DF.  Relationships of the mecholyl test, premorbid asocial functioning and long-term outcome in schizophrenia.  J Nerv Ment Dis 1970; 150: 301-306.

  65. Klein DF, Honigfeld G, Burnett LL, Steckler M, Leader M, Forman M.  Automating the psychiatric case study.  Compr Psychiatry 1970; 11(6): 518-523.

  66. Pollack M, Woerner M, Klein DF.  A comparison of twin and sibling studies for a developmental theory of schizophrenia.  Acta Geneticae Medical et Gamellologia 1970; 19: 303-304.

  67. Honigfeld G & Klein DF.  The Hillside Hospital treatment evaluation program: Clinical and basic research.  Suppl to Dis Nerv Syst 1970; 31: 11.

  68. Woerner MG, Pollack M, Klein DF.  Birth weight and length in schizophrenics, personality disorders, and their siblings.  Br J Psychiatry 1970; 118: 461-464.

  69. Rosen B, Klein DF, Gittelman-Klein R.  The prediction of rehospitalization:  The relationship between age of first psychiatric treatment contact, marital status and premorbid asocial adjustment.  J Nerv Ment Dis 1971; 52(1): 17-22.

  70. Rifkin A, Quitkin F, Carrillo C, Klein DF.  Very high dosage fluphenazine for non-chronic treatment-refractory patients.  Arch Gen Psychiatry 1971; 25: 398-403.

  71. Rosen B, Engelhardt DM, Freedman N, Margolis R, Klein DF.  The hospitalization proneness scale as a predictor of response to phenothiazine treatment (II): Delay of psychiatric hospitalization.  J Nerv Ment Dis 1971; 152(6): 405-411.

  72. Cohen M & Klein DF.  A measure of severity of multi-drug use.  Intl Pharmacopsychiatry 1971; 6: 83-91.

  73. Blumberg AG, Cohen M, Heaton AM, Klein DF.  Covert drug abuse among voluntary hospitalized psychiatric patients.  JAMA 1971; 217(12): 1659-166l.

  74. Gittelman-Klein R & Klein DF.  Controlled imipramine treatment of school phobia.  Arch Gen Psychiatry 1971; 25: 204-207.

  75. Saraf K & Klein DF.  The safety of a single daily dose schedule for imipramine.  Am J Psychiatry 1971; 128(4): 115-116.

  76. Klein DF.  Youthful rebels - diagnosis and treatment.  Adolescence 1972; 7(27): 351-369.

  77. Struve FA, Becka DR, Klein DF.  B-Mitten EEG pattern and process and reactive schizophrenia:  A replication.  Arch Gen Psychiatry 1972; 26: 189-192.

  78. Rifkin A, Levitan SJ, Galewski J, Klein DF.  Emotionally unstable character disorder; A follow-up study (I):  Description of patients and outcome.  Biol Psychiatry 1972; 4(1): 65-79.

  79. Rifkin A, Levitan SJ, Galewski J, Klein DF.  Emotionally unstable character disorder; A follow-up study (II):  Prediction of outcome.  Biol Psychiatry 1972; 4(1): 81-88.

  80. Struve FA, Klein DF, Saraf KR.  Electroencephalographic correlates of suicide ideation and attempts.  Arch Gen Psychiatry 1972; 27: 363-365.

  81. Feldman S, Klein DF, Honigfeld G.  The reliability of a decision tree technique applied to psychiatric diagnosis.  Biometrics 1972; 28: 831-840.

  82. Cohen M & Klein DF.  Social values and drug use among psychiatric patients.  Am J Psychiatry 1972; 128(8): 1017-1019.

  83. Cohen M & Klein DF.  Age of onset of drug abuse in psychiatric inpatients.  Arch Gen Psychiatry, 1972; 26(3): 226-270.

  84. Quitkin F, Rifkin A, Kaplan J, Klein DF.  Phobic anxiety syndrome complicated by drug dependence and addiction:  A treatable form of drug abuse.  Arch Gen Psychiatry 1972; 27(2): 159-162.

  85. Rifkin A, Quitkin F, Carrillo C, Blumberg AG, Klein DF.  Lithium carbonate in emotionally unstable character disorders.  Arch Gen Psychiatry 1972; 27: 519-523.

  86. Klein DF.  Logic in the use of psychiatric diagnosis.  Psychotherapy and Social Science Review 1972; 6(11): 21-23.

  87. Quitkin F, Rifkin A, Klein DF.  Literature review and proposal for lithium prophylaxis studies.  J Natl. Assoc Private Psychiatric Hospitals 1972; 4(3): 11-15.

  88. Struve FA, Becka DR, Klein DF.  The B-Mitten EEG pattern in process and reactive schizophrenia and affective states.  Clinical Electroencephalography 1972; 3(3): 136-144.

  89. Woerner MG, Pollack M, Klein DF.  Pregnancy and birth complications in psychiatric patients:  a comparison of schizophrenic and personality disorder patients with their siblings.  Acta Psychiatrica Scandinavica 1973; 49(6): 712-721.

  90. Gittelman-Klein R & Klein DF.  School phobia:  Diagnostic considerations in the light of imipramine effects.  J Nerv Ment Dis 1973; 156(3): 199-215.

  91. Rifkin A, Kurtin S, Quitkin F, Klein DF.  Lithium-induced folliculitis.  Am J Psychiatry 1973; 130(9): 1018-1019.

  92. Mendel JG & Klein DF.  Utilization of the psychiatric consultation service in a large city hospital.  Psychosomatics 1973; 14(1): 57-58.

  93. Quitkin F, Rifkin A, McKay L, Klein DF.  Scapegoating in hospitalized adolescents:  A behavioral phenomena associated with schizophrenia with premorbid asociality.  Arch Gen Psychiatry 1973; 28(5): 680-682.

  94. Honigfeld G & Klein DF.  Hillside Hospital Patient Progress Record:  Explorations in clinical management by objective and exception.  Evaluation Special Mono 1973; 1: 19-22.

  95. Klein DF & Rosen B.  Premorbid asocial adjustment and  response to phenothiazine treatment among schizophrenic inpatients.  Arch Gen Psychiatry 1973; 29: 480-485.

  96. Rifkin A, Quitkin F, Klein DF.  Organic brain syndrome during lithium carbonate treatment.  Compr Psychiatry 1973; 4(3): 251-254.

  97. Hoffer A, Cohen M, Klein DF.  A classification of patient-peer interaction.  Compr Psychiatry 1973; 14(3): 255-262.

  98. Klein DF, Honigfeld G, Feldman S.  Prediction of drug effect in personality disorders. J Nerv Mental Dis 1973; 156(3): 183-97.

  99. Saraf KR, Klein DF, Gittelman R, Groff S.  Imipramine side effects in children.  Psychopharmacologia 1974; 37(3): 265-274.




  100. Cohen M & Klein DF.  Post-hospital adjustment of psychiatrically hospitalized drug users.  Arch Gen Psychiatry 1974; 31: 221-227.

  101. Klein DF.  What should the package insert be?  Arch Gen Psychiatry 1974; 31: 735-741.

  102. Woerner MG & Klein DF.  14 and 6 per second positive spiking:  Developmental and clinical correlates in psychiatric patients and their siblings.  J Nerv Ment Dis 1974; 159: 356-361.

  103. Klein DF.  Endogenomorphic depression:  A conceptual and terminological revision.  Arch Gen Psychiatry 1974; 31: 447-451.

  104. Klein DF.  Comment on "On molecular environment of the mind:  An orthomolecular theory" by Linus Pauling.  Am J Psychiatry 1974; 131: 1263-1265.

  105. Rifkin A, Quitkin F, Blumberg AG, Klein DF.  The effect of lithium on thyroid functioning:  A controlled study.  J Psychiatric Res 1974; 10: 115-120.

  106. Quitkin F, Gittelman R, Rifkin A, Klein DF.  Atypical signs of relapse in affective disorders.  Dis Nerv Sys 1975; 36: 145-146.

  107. Klein DF, Ross DC, Feldman S.  Analysis and display of psychopharmacological data. J Psychiatric Res 1975; 12: 125-147.

  108. Quitkin F, Rifkin A, Kaplan JH, Klein DF.  Treatment of acute schizophrenia with ultra-high dose fluphenazine:  A failure at shortening time on a crisis intervention unit.  Compr Psychiatry 1975; 16(3): 279-283.

  109. Rifkin A, Quitkin F, Howard A, Klein DF.  A study of abrupt lithium withdrawal.  Psychopharmacologia 1975; 44: 157-158.

  110. Prichep L, Cohen M, Kaplan J, Karlin E, Klein DF.  Psychiatric evaluation services to court referred drug users.  Am J Drug & Alcohol Abuse 1975; 2(2): 197-213.

  111. Quitkin F, Rifkin A, Klein DF.  Very high dosage vs. standard dosage fluphenazine in schizophrenia:  A double-blind study of nonchronic treatment-refractory patients.  Arch Gen Psychiatry 1975; 32(10): 1276-1281.

  112. Rifkin A, Quitkin F, Klein DF.  Akinesia:  A poorly recognized drug-induced extrapyramidal behavior disorder.  Arch Gen Psychiatry 1975; 32(5): 672-674.

  113. Klein DF & Gittelman R.  Problems in the diagnosis of minimal brain dysfunction and hyperkinetic syndrome.  International J Ment Health 1975; 4: 45-60.

  114. Gittelman-Klein R & Klein DF.  Are behavioral and psychometric changes related in methylphenidate treated hyperactive children?  International J Ment Health 1975; 4: 182-198.

  115. Katz S, Saraf K, Gittelman-Klein R, Klein DF.  Clinical pharmacological management of hyperkinetic children.  International J Ment Health 1975; 4(1-2): 157-181.

  116. Klein DF.  Indications for specific treatments of depressions.  Psychopharm Bull 1975; 11(3): 3-13.

  117. Willner AE, Rabiner CJ, Wisoff BG, Hartstein M, Struve FA, Klein DF.  Analogical reasoning and postoperative outcome:  Predictions for patients scheduled for open heart surgery.  Arch Gen Psychiatry 1976; 33(2): 255-259.

  118. Cohen M, Howard A, Klein DF, Newfield K.  Evaluating outcome criteria used in methadone maintenance programs.  International J Addictions 1976; 11(2): 283-294.

  119. Gittelman-Klein R, Klein DF.  Methylphenidate effects in learning disabilities:  Psychometric changes.  Arch Gen Psychiatry 1976; 33(6): 655-668.

  120. Quitkin F, Rifkin A, Klein DF.  Prophylaxis of affective disorders:  Current status of knowledge.  Arch Gen Psychiatry 1976; 33(3): 337-341.

  121. Struve FA & Klein DF.  Diagnostic implications of the B-Mitten EEG Pattern: Relationship to primary and secondary affective dysregulation.  Biol Psychiatry 1976; 11(5): 599-611.

  122. Rosen B, Katzoff A, Carillo C, Klein DF.  Clinical effectiveness of "short" vs "1ong" psychiatric hospitalization (I):  Inpatient results.  Arch Gen Psychiatry 1976; 33(6): 1316-1322.

  123. Struve FA, Saraf KR, Arko RS, Klein DF, Becka DR.  Electroencephalographic correlates of oral contraceptive use in psychiatric patients.  Arch Gen Psychiatry 1976; 33(6): 741-750.

  124. Quitkin F, Rifkin A, Klein DF.  Neurologic soft signs in schizophrenia and character disorders; Organicity in schizophrenia with premorbid asociality and emotionally unstable character disorders.  Arch Gen Psychiatry 1976; 33(7): 845-853.

  125. Gittelman-Klein R, Klein DF, Katz S, Saraf K, Pollack E.  Comparative effects of methylphenidate and thioridazine in hyperkinetic children.  Arch Gen Psychiatry 1976; 33(10): 1217-1231.

  126. Willner AE, Rabiner CJ, Wisoff BG, Fishman J, Rosen B, Hartstein M, Klein DF.  Analogy tests and psychopathology at follow-up after open heart surgery.  Biol Psychiatry 1976; 11: 687-696.

  127. Gittelman-Klein R, Klein DF, Abikoff H, Katz S, Gloisten AC, Katz W.  Relative efficacy of methylphenidate and behavior modification in hyperkinetic children:  An interim report.  J Abnorm Child Psychiatry 1976; 4: 361-379.

  128. Leader M & Klein DF.  Reflections on instituting a computerized psychosocial history in a clinical facility.  Compr Psychiatry 1977; 18(5): 489-495.

  129. Rifkin A, Quitkin F, Rabiner CJ, Klein DF.  Fluphenazine decanoate, fluphenazine hydrochloride given orally, and placebo in remitted schizophrenics (I):  Relapse rates after one year.  Arch Gen Psychiatry 1977; 34(1): 43-47.

  130. Quitkin F, Rifkin A, Gochfeld L, Klein DF.  Tardive dyskinesia:  Are first signs reversible?  Am J Psychiatry 1977; 134: 84-87.

  131. Rifkin A, Quitkin F, Klein DF.  Fluphenazine decanoate, oral fluphenazine and placebo in treatment of remitted schizophrenics (II):  Rating scale data.  Arch Gen Psychiatry 1977; 34(10): 1215-1219.

  132. Abikoff H, Gittelman-Klein R, Klein DF.  Validation of a classroom observation code for hyperactive children.  J Consult & Clin Psychology 1977; 45(5): 722-783.

  133. Mattes J, Rosen B, Klein DF.  Comparison of the clinical effectiveness of "short" vs. "long" stay psychiatric hospitalization (II):  Results of a three-year post hospital follow-up.  J Nerv & Ment Dis 1977; 165(6): 387-394.

  134. Mattes JA, Rosen B, Klein DF, Millan D.  Comparison of the clinical effectiveness of "short" vs "long" stay psychiatric hospitalization (III):  Further results of a three-year post hospital follow-up.  J Nerv & Ment Dis 1977; 165(6): 395-401.

  135. Klein DF.  Evaluation methodology.  J Addictions 1977; 12(7): 837-849.

  136. Saraf KR, Klein DF, Gittelman-Klein R, Gootman N, Greenhill P.  EKG effects of imipramine treatment in children.  J Acad Child Psych 1978; 17(1): 60-69.

  137. Rifkin A, Quitkin F, Kane J, Struve F, Klein DF.  Are prophylactic antiparkinson drugs necessary? A controlled study of procyclidine withdrawal.  Arch Gen Psychiatry 1978; 35(4): 483-489.

  138. Kane JM, Quitkin F, Rifkin A, Klein DF.  Comparison of incidence and severity of extrapyramidal side effects with fluphenazine enanthate and fluphenazine decanoate.  Am J Psychiatry 1978; 135(12): 1539-1542.

  139. Quitkin F, Rifkin A, Klein DF.  Imipramine response in deluded depressive patients.  Am J Psychiatry 1978; 135(7): 806-811.

  140. Zitrin CM, Klein DF, Woerner MG.  Behavior therapy, supportive psychotherapy, imipramine and phobias.  Arch Gen Psychiatry 1978; 35(3): 307-316.

  141. Quitkin F, Rifkin A, Kane J, Ramos-Lorenzi JR, Klein DF.  Long-acting oral vs injectable antipsychotic drugs in schizophrenia:  A one-year double-blind comparison in multiple episode schizophrenics.  Arch Gen Psychiatry 1978; 35(7): 889-892.

  142. Quitkin F, Rifkin A, Kane J, Ramos-Lorenzi JR, Klein DF.  Prophylactic effect of lithium and imipramine in unipolar and bipolar II patients:  A preliminary report.  Am J Psychiatry 1978; 135(5): 570-572.

  143. Drues J, Hargreaves WA, Glick ID, Klein DF.  Premorbid asocial adjustment and outcome in schizophrenia.  J Nerv & Ment Dis 1978; 166(12): 881-884.

  144. Kane J, Rifkin A, Quitkin F, Klein DF.  Extrapyramidal side effects with lithium treatment.  Am J Psychiatry 1978; 135(7): 851-853.

  145. Liebowitz M, Neutzel E, Bowser A, Klein DF.  Phenelzine and delusions of parasitosis:  A case report.  Am J Psychiatry 1978; 135(12): 1565-1566.

  146. Ross DC & Klein DF.  A comparison of analysis of covariance and the O technique as applied to illustrative psychopharmacological data.  J Psychiatric Res 1979; 15: 67-75.

  147. Klein DF.  Comments on "Science and anti-science in confrontation:  New responsibilities and new opportunities by Bernard Schoenberg".  Man & Medicine 1979; 4(2): 103-105.

  148. Quitkin F, Rifkin A, Klein DF.  Monoamine oxidase inhibitors:  A review of antidepressant effectiveness.  Arch Gen Psychiatry 1979; 36(7): 749-760.

  149. Mattes J, Klein DF, Millan D, Rosen B.  Comparison of the clinical effectiveness of "short" vs "long" stay psychiatric hospitalization (IV):  Predictors of differential benefit.  J Nerv & Ment Dis 1979; 167(3): 175-181.

  150. Kane J, Rifkin A, Quitkin F, Nayak D, Saraf K, Ramos-Lorenzi JR, Klein DF, Sachar EJ.  Low dose fluphenazine decanoate in maintenance treatment of schizophrenics.  Psychiatry Res 1979; 1: 341-348.

  151. Rifkin A, Quitkin F, Kane J, Klein DF, Ross D.  The effect of fluphenazine upon social and vocational functioning in remitted schizophrenics.  Biol Psychiatry 1979; 14(3): 499-508.

  152. Liebowitz MR & Klein DF.  Assessment and treatment of phobic anxiety.  J Clin Psychiatry 1979; 40(11): 486-492.

  153. Dorsey R, Ayd F, Cole J, Klein DF, Simpson G, Tupin J, DiMascio A.  Psychopharmacological screening criteria development project.  JAMA 1979; 241 (10): 1021-1031.  (Also in Psychotropic Drugs.  (1979)  Towery OB & Brands AB. (Eds.)  DHEW # (ADA) Publications, pp 46-71.)

  154. Liebowitz MR & Klein DF.  Hysteroid dysphoria.  Psychiatric Clinics of North America 1979; 2(3): 555-575.

  155. Zitrin C, Klein DF, Woerner M.  Treatment of agoraphobia with group exposure in vivo and imipramine.  Arch Gen Psychiatry 1980; 37(1): 63-72.

  156. Rifkin A, Saraf K, Kane J, Ross D, Klein DF.  Comparison of trimipramine and imipramine:  A controlled study.  J Clin Psychiatry 1980; 41(4): 124-129.

  157. Quitkin F, Rifkin A, Tsuang M, Kane J, Klein DF.  Can schizophrenia with premorbid asociality be genetically distinguished from the other forms of schizophrenia?  Psychiatry Res 1980; 2: 99-105.

  158. Klein DF.  Psychosocial treatment of schizophrenia or psychosocial help for people with schizophrenia?  Schizophrenia Bull 1980; 6(1): 122-130.

  159. Stewart JW, Quitkin F, Fyer A, Rifkin A, McGrath P, Liebowitz MR, Rosnick L, Klein DF.  Efficacy of desipramine in endogenomorphically depressed patients.  J Affective Disorders 1980; 2: 165-176.

  160. Klein DF.  A slippery slope.  Perspectives in Biology & Medicine. Winter 1980; Part 2: S115-S119.

  161. Klein DF.  Anxiety reconceptualized.  Compr Psychiatry 1980; 21(6): 411-427.

  162. Abikoff H, Gittelman R, Klein DF.  Classroom observation code for hyperactive children:  A replication of validity.  J Consult & Clin Psychiatry 1980; 48(5): 555-565.

  163. Klein DF & Rabkin JG.  Mental health policy; Implications for scientific research on drugs.  Annual Science and Technology Report to the Congress. 1980.  Washington, DC:  National Science Foundation.

  164. Liebowitz MR & Klein DF.  Drug therapy and/or psychotherapy for depression.  The Female Patient 1981; 6: 25-29.

  165. Rifkin A, Klein DF, Dillon D, Levitt M.  Blockade by imipramine or desipramine of panic induced by sodium lactate.  Am J Psychiatry 1981; 138(5): 676-677.

  166. Gorman JM, Fyer AF, Gliklich J, King D, Klein DF.  Effect of sodium lactate on panic disorder patients with mitral valve prolapse.  Am J Psychiatry 1981; 138(2): 247-249.

  167. Halbreich U, Weinberg U, Stewart JW, Klein DF, Quitkin F.  An inverse correlation between serum levels of desmethylimipramine and melatonin-like immunoreactivity in DMI-responsive depressives.  Psychiatry Res 1981; 4: 109-113.

  168. Liebowitz MR & Klein DF.  Interrelationship of hysteroid dysphoria and borderline personality disorder.  Psychiatric Clinics of North America 1981; 4(l): 67-87.

  169. McGrath PJ, Quitkin F, Stewart JW, Liebowitz MR, Fyer A, Davies S, Klein DF.    Novel antidepressants:  A clinical trial of mianserin.  Psychopharm Bull 1981; 17(1): 2l-23.

  170. Stewart JW, Quitkin F, Liebowitz MR, McGrath PJ, Klein DF.  Efficacy of desipramine in mildly depressed patients:  A double-blind placebo-controlled trial.  Psychopharm Bull 1981; 17(1): 136-138.

  171. Gorman JM, Fyer AJ, Gliklich J, King D, Klein DF.  Effect of imipramine on the prolapsed mitral valves of patients with panic disorder.  Am J Psychiatry 1981; 138(7): 977-978.

  172. Liebowitz MR, Fyer AJ, McGrath PJ & Klein DF.  Clonidine treatment of panic disorder.  Psychopharm Bull 1981; 17(3): 122-123.

  173. Liebowitz MR & Klein DF.  Differential diagnosis and treatment of panic attacks and phobic states.  The Annual Review of Medicine 1981; 32: 83-599.

  174. Liebowitz MR, Quitkin FM, Stewart JW, McGrath PJ, Harrison W, Schwartz D, Rabkin J, Tricamo E & Klein DF.  Phenelzine and imipramine in atypical depression.  Psychopharm Bull 1981; 17(3): 159-16l.

  175. Quitkin FM, Schwartz DG, Liebowitz MR, Stewart JW, McGrath PJ, Halpern F, Puig-Antich J, Tricamo E, Harrison W, Sacher EJ & Klein DF.  Atypical depressives:  A preliminary report of antidepressant response and sleep patterns.  Psychopharm Bull 1981; 18(1): 78-80.

  176. Quitkin F, Kane JM, Rifkin A, Ramos-Lorenzi J, Saraf K, Howard A, Klein DF.    Lithium and imipramine in the prophylaxis of unipolar and bipolar II depression:  A prospective placebo-controlled comparison.  Psychopharm Bull 1981; 17(1): 142-144.

  177. Kane JM, Quitkin F, Rifkin A, Ramos-Lorenzi J, Saraf K, Howard A, Klein DF.    Prophylactic lithium with and without imipramine for bipolar I patients:  A double-blind study.  Psychopharm Bull 1981; 17(l): 144-145.

  178. Wender PH & Klein DF.  The promise of biological psychiatry.  Psychology Today Feb. 1981: 25-41.

  179. Strain JJ, Liebowitz MR, Klein DF.  Anxiety and panic attacks in the medically ill.  Psychiatric Clinics of North America 1981; 4(2): 333-350.

  180. Halbreich U, Sachar EJ, Asnis GM, Quitkin F, Nathan RS, Halpern FS, Klein DF.  Growth hormone response to dextroamphetamine in depressed patients and normal subjects.  Arch Gen Psychiatry 1982; 39(2): 189-192.

  181. Frances A & Klein DF.  DSM-III Case Studies - Anxious, precise, demanding man seeks help soon after marriage.  Hosp Comm Psychiatry 1982; 33(2): 89-90.

  182. Karoum F, Chuang L, Eisler T, Calne DS, Liebowitz MR, Quitkin FM, Klein DF, Wyatt RJ.  Metabolism of (-) deprenyl to amphetamine and methamphetamine may be responsible for deprenyl's therapeutic benefit:  A biochemical assessment.  Neurology 1982; 32: 503-509.

  183. Klein DF.  Panic, separation anxiety and endorphins.  Behvrl and Brn Sciences 1982; 3: 436-437.

  184. Klein DF.  Editorial.  Diagnosis and treatment prescription:  Psychiatry's special value.  Psychosom 1982; 23(8): 791-795.

  185. Klein DF.  Medication in the treatment of panic attacks and phobic states.  Psychopharm Bull 1982; 18(4): 85-90.

  186. Liebowitz MR & Klein DF.  Unresolved issues in the treatment of agoraphobia with panic attacks.  Psychopharm Bull 1982; 18(4): 109-114.

  187. Stewart JW, Quitkin FM, McGrath PJ, Liebowitz MR, Klein DF.  Efficacy of mianserin in mildly depressed patients.  Psychopharm Bull 1982; 18(1): 68-70.

  188. McGrath PJ, Quitkin FM, Blood D, Liebowitz MR, Stewart J, Fyer AJ, Klein DF.  The effect of mianserin on cardiac conduction:  A controlled study.  Psychopharm Bull 1982; 18(1): 71-72.

  189. Gittelman R, Klein DF, Feingold I.  Children with reading disorders II:  Effects of methylphenidate in combination with reading remediation.  J Child Psychol & Psychiatry 1983; 24(2): 193-212.

  190. Zitrin CM, Klein DF, Woerner MG, Ross DC.  Treatment of Phobias (I):   Comparison of imipramine hydrochloride and placebo.  Arch Gen Psychiatry 1983; 40(2): 125-138.

  191. Klein DF, Zitrin CM, Woerner MG, Ross DC.  Treatment of Phobias (II):  Behavior therapy and supportive psychotherapy:  Are there any specific ingredients?  Arch Gen Psychiatry 1983; 40(2): 139-145.

  192. Stewart JW, Quitkin FM, Liebowitz MR, McGrath PJ, Harrison WM, Klein DF.  Efficacy of desipramine in depressed outpatients:  Response according to research diagnostic criteria diagnoses and severity of illness.  Arch Gen Psychiatry 1983; 40(2): 202-207.

  193. Liebowitz MR, Karoum F, Quitkin FM, Davies SO, Stewart JW, McGrath PJ, Harrison W, Schwartz D, Levitt M, Linnoila M, Wyatt R, Palij M, Klein DF.  Biochemical effects of deprenyl.  Psychopharm Bull 1983; 19(3): 336-339.

  194. Liebowitz MR, Fyer AJ , Appleby I, Levitt M, Gorman J, Dillon D, Levy G, Anderson S, Davies SO, Palij M, Klein DF.  Lactate provocation of panic attacks.  Psychopharm Bull 1983; 19(3): 476-478.

  195. Harrison W, Cooper TB, Quitkin FM, Liebowitz MR, McGrath PJ, Stewart JW, Klein DF.  Tyramine sulfate excretion test in depressive illness.  Psychopharm Bull 1983; 19(3): 503-504.

  196. Klein DF.  Is the anti-panic activity of antidepressant medication a reflection of antidepressant effects?  Integrative Psychiatry 1983; 1(1): 26-27.

  197. Kass F, Charles E, Klein DF, Cohen P.  Discordance between the SCL-90 and therapists' psychopathology ratings:  Implications for clinical assessment.  Arch Gen Psychiatry 1983; 40(4): 389-393.

  198. Fyer A, Liebowitz MR, Gorman JM, Davies SO, Klein DF.  Sodium lactate reinfusion of recovered lactate-vulnerable panic disorder patients.  21st Annual Meeting of the ACNP - 1982 Poster Session.  Psychopharm Bull 1983; 19(4): 576-577.

  199. Gorman JM, Levy G, Liebowitz MR, McGrath P, Appleby I, Dillon D, Davies SO, Klein DF.  Intravenous propranolol during sodium lactate infusion. 21st Annual Meeting of the ACNP - 1982 Poster Session.  Psychopharm Bull 1983; 19(4): 577-578.





  200. Klein DF.  Editorial.  The specificity of psychotherapy.  Biol Psychiatry 1983; 18(10): 1105.

  201. Gorman JM, Levy G, Liebowitz MR, McGrath P, Appleby IL, Dillon DJ, Davies SO, Klein DF.  Effect of acute beta-adrenergic blockade on lactate-induced panic.  Arch Gen Psychiatry 1983; 40(10): 1079-1082.

  202. Liebowitz MR, Quitkin FM, Stewart JW, McGrath P, Harrison W, Rabkin J, Tricamo E, Markowitz JS, Klein DF.  Phenelzine vs imipramine in atypical depression:  A preliminary report.  Arch Gen Psychiatry 1984; 41(7): 669-677.

  203. Lindemann CG, Zitrin C, Klein DF.  Thyroid dysfunction in phobic patients.  Psychosomatics 1984; 25(8): 603-606.

  204. Harrison W, Cooper TB, Stewart JW, Quitkin FM, McGrath PJ, Liebowitz MR, Rabkin JR, Markowitz JS, Klein DF.  The tyramine challenge test as a marker for melancholia.  Arch Gen Psychiatry 1984; 41(7): 681-685.

  205. Liebowitz MR, Gorman JM, Fyer AJ, Dillon DJ, Klein DF.  Effects of naloxone on patients with panic attacks.  Am J Psychiatry 1984; 141(8): 995-997.

  206. Liebowitz MR, Quitkin FM, Stewart JW, McGrath PJ, Harrison W, Rabkin JG, Tricamo E, Markowitz JS, Klein DF.  Psychopharmacological validation of atypical depression.  J Clin Psychiatry 1984; 45(7) Sect. 2: 22-25.

  207. Gorman JM, Martinez JM, Liebowitz MR, Fyer AJ, Klein DF.  Hypoglycemia and panic attacks.  Am J Psychiatry 1984; 141(3): 101-102.

  208. Liebowitz MR, Fyer AJ, Gorman JM, Dillon D, Appleby IL, Levy G, Anderson S, Levitt M, Palij M, Davies SO, Klein DF.  Lactate provocation of panic attacks (I):  Clinical & behavioral findings.  Arch Gen Psychiatry 1984; 41(8): 764-770.

  209. McGrath PJ, Quitkin FM, Harrison W, Klein DF.  Treatment of melancholia with tranylcypromine.  Am J Psychiatry 1984; 141(2): 288-289.

  210. Halperin JM, Gittelman R, Klein DF, Rudel RG.  Reading-disabled hyperactive children:  A distinct subgroup of attention deficit disorder with hyperactivity?  J Abn Child Psychol 1984; 12(1): 1-14.

  211. Gittelman-Klein R & Klein DF.  Relationship between separation anxiety and panic and agoraphobic disorders.  July 1983.  Vienna, Austria:  VII World Congress of Psychiatry.  Also in:  Psychopathology 1984; 17(1): 56-65.

  212. Fyer AJ, Gorman JM, Martinez J, Levitt M, Liebowitz MR, Klein DF.  Sodium lactate infusion, panic attacks and ionized calcium.  Biol Psychiatry 1984; 19(10): 1437-1447.

  213. Liebowitz MR, Gorman J, Fyer A, Levitt M, Levy G, Dillon D, Appleby I, Anderson S, Palij M, Davies SO, Klein DF.  Biological accompaniments of lactate-induced panic.  Psychopharm Bull 1984; 20(1): 43-44.

  214. Klein DF & Gorman J.  Panic disorders and mitral valve prolapse.  J Clin Psychiatry, Monograph Series 1984; 2(1): 14-17.

  215. Liebowitz MR, Fyer AJ, Gorman JM, Dillon D, Appleby IL, Levy G, Anderson S, Levitt M, Palij M, Davies SO, Klein DF.  Provocation of panic attacks by sodium lactate infusion.  J Clin Psychiatry 1984; Monog Ser 2(1): 18-20.

  216. Gorman JM, Askanazi J, Liebowitz MR, Fyer AJ, Stein J, Kinney JM, Klein DF.  Response to hyperventilation in a group of patients with panic disorder.  Am J Psychiatry 1984; 141(7): 857-861.

  217. Klein DF.  Psychopharmacologic treatment of panic disorder.  Psychosomatics 1984; 25(10): 32-36.

  218. Liebowitz MR, Quitkin FM, Stewart JM, McGrath P, Harrison W, Rabkin JG, Klein DF.  Psychopharmacological dissection of nonendogenous depression.  Psychopharm Bull 1984; 20(3): 390-392.

  219. Gorman JM, Liebowitz MR, Stein J, Fyer AJ, Klein DF.  Insulin levels during lactate infusion.  Am J Psychiatry 1984; 141(12): 1621-1622.

  220. Garakani H, Zitrin CM, Klein DF.  Treatment of panic disorder with imipramine alone.  Am J Psychiatry 1984; 141(3): 446-448.

  221. Fyer AJ, Liebowitz MR, Gorman JM, Davies SO, Klein DF.  Lactate vulnerability of remitted panic patients.  Psychiatry Res 1985; 14: 143-148.

  222. Liebowitz MR, Gorman JM, Fyer AJ, Levitt M, Dillon D, Levy G, Appleby IL, Anderson S, Palij M, Davies SO, Klein DF.  Lactate provocation of panic attacks (II):  Biochemical and physiological findings.  Arch Gen Psychiatry 1985; 42(7): 709-719.

  223. Liebowitz MR, Gorman JM, Fyer AJ, Klein DF.  Social phobia:  Review of a neglected anxiety disorder.  Arch Gen Psychiatry 1985; 42(7): 729-736.

  224. Liebowitz MR, Fyer AJ, Gorman JM, Dillon D, Davies S, Stein J, Cohen BS, Klein DF.  Specificity of lactate infusions in social phobia vs panic disorders.  Am J Psychiatry 1985; 142(8): 947-949.

  225. Liebowitz MR, Quitkin FM, Stewart JW, McGrath PJ, Harrison W, Rabkin JR, Tricamo E, Markowitz JS, Klein DF.  Effect of panic attacks on the treatment of atypical depressives.  Psychopharm Bull 1985; 21(3): 558-562.

  226. Liebowitz MR, Gorman J, Fyer A, Campeas R, Levin A, Davies S, Klein DF.  Psychopharmacological treatment of social phobia.  Psychopharm Bull 1985; 21(3): 610-6l4.

  227. Gorman J, Liebowitz MR, Fyer AJ, Levitt M, Baron M, Davies S, Klein DF.  Platelet monoamine oxidase activity in patients with panic disorder.  Biol Psychiatry 1985; 20(8): 852-857.

  228. Gorman JM, Fyer AJ, Ross DC, Cohen BS, Martinez JM, Liebowitz MR, Klein DF.  Normalization of venous pH, pCO2 and bicarbonate levels after blockade of panic attacks.  Psychiatry Res 1985; 14: 57-65.

  229. Gorman JM, Liebowitz MR, Fyer AJ, Dillon D, Davies SO, Klein DF.  Lactate infusions in obsessive-compulsive disorder.  Am J Psychiatry 1985; 142(7): 864-866.

  230. Gorman JM, Dillon D, Fyer AJ, Liebowitz MR, Klein DF.  The lactate infusion model.  Psychopharm Bull 1985; 21(3): 428-433.

  231. Gorman JM, Liebowitz MR, Fyer AJ, Campeas R, Klein DF.  Treatment of social phobia with atenolol.  J Clin Psychopharm 1985; 5(5): 298-301.

  232. Gittelman R & Klein DF.  Hillside behavior rating scale (Behavior during testing).  Psychopharm Bull 1985; 21(4): 898-899.

  233. Liebowitz MR, Gorman JM, Fyer AJ, Dillon D, Levitt M, Klein DF.  Possible mechanisms for lactate's induction of panic.  Am J Psychiatry 1986; 143(4): 495-502.

  234. Janowsky DS, Glick ID, Lash L, Mitnick L, Klein DF, Goodwin FK, Hanin I, Nemeroff C, Robins L.  Psychobiology and psychopharmacology:  Issues in clinical research training. J Clin Psychopharm 1986; 6(1): 1-7.

  235. Liebowitz MR, Fyer AJ, Gorman JM, Campeas R, Levin A, Davies SO, Goetz D, Klein DF.  Alprazolam in the treatment of panic disorders.  J Clin Psychopharm 1986; 6(l): 13-20.

  236. Klein DF & Quitkin FM.  Problems with and promises of monoamine oxidase inhibitors.  Psychopharm Bull 1986; 22(1): 7-1l.

  237. Gorman JM, Shear MK, Devereux RB, King DL, Klein DF.  Prevalence of mitral valve prolapse in panic disorder:  Effect of echocardiographic criteria.  Psychosom Med 1986; 48(3/4): 167-171.

  238. Mannuzza S, Fyer AJ, Klein DF, Endicott J.  Schedule for affective disorders and schizophrenia-lifetime version modified for the study of anxiety disorders (SADS-LA):  Rationale and conceptual development.  J Psychiatric Res 1986; 20(4): 317-325.

  239. Kahn JP, Stevenson E, Topol P, Klein DF.  Agitated depression, alprazolam and panic anxiety.  Am J Psychiatry 1986; 43(9): 1172-1173.

  240. Gorman JM, Cohen BS, Liebowitz MR, Fyer AJ, Ross D, Davies SO, Klein DF.  Blood gas changes and hypophosphatemia in lactate-induced panic.  Arch Gen Psychiatry 1986; 43(11): 1067-1075.

  241. Liebowitz MR, Gorman JM, Fyer AJ, Dillon D, Klein DF.  L'induction pharmacologique des crises de Les nouveaux aspects de l'anxiete, Symposium International.  Actualities Medicales Internationales en Psychiatrie 1986; Suppl 22: 29-34.

  242. Levin AP, Fyer AJ, Gorman JM, Liebowitz MR, Klein DF.  Troubles paniques.  Les nouveaux aspects de l'anxiete, Symposium International.  Actualities Medicales Internationales en Psychiatrie 1986; Suppl 22: 90-96.

  243. Liebowitz MR, Fyer AJ, Gorman JM, Klein DF.  Recent developments in the understanding and pharmacotherapy of panic attacks.  Psychopharm Bull 1986; 22(3): 792-796.

  244. Gorman JM, Liebowitz MR, Fyer AJ, Klein DF.  Possible respiratory abnormalities in panic disorder.  Psychopharm Bull 1986; 22(3): 797-801.

  245. Rabkin JG, Markowitz JS, Stewart J, McGrath P, Harrison W, Quitkin FM, Klein DF.  How blind is blind?  Assessment of patient and doctor medication guesses in a placebo-controlled trial of imipramine and phenelzine.  Psychiatric Res 1986; 19: 175-86.

  246. Gorman JM, Liebowitz MR, Fyer AJ, Goetz D, Campeas R, Fyer MR, Davies SO, Klein DF.  An open trial of fluoxetine in the treatment of panic attacks.  J Clin Psychopharm 1987; 7(5): 329-332.

  247. Kahn JP, Drusin RE, Klein DF.  Idiopathic cardiomyopathy and panic disorder:  Clinical association in cardiac transplant candidates.  Am J Psychiatry 1987; 44(10): 1327-1330.

  248. Levin AP, Doran AR, Liebowitz MR, Fyer AJ, Gorman JM, Klein DF, Paul SM.  Pituitary adrenocortical unresponsiveness in lactate-induced panic.  Psychiatric Res 1987; 21(1): 23-32.

  249. Fyer AJ, Liebowitz MR, Gorman JM, Campeas R, Levin A, Davies SO, Goetz D, Klein DF.  Discontinuation of alprazolam treatment in panic patients.  Am J Psychiatry 1987; 144(3): 303-308.

  250. Dillon DJ, Gorman JM, Liebowitz MR, Fyer AJ, Klein DF.  The measurement of lactate-induced panic and anxiety.  Psychiatric Res 1987; 20: 97-105.

  251. Klein DF, Ross DC, Cohen P.  Panic and avoidance in agoraphobia:  Application of PATH analysis to treatment studies.  Arch Gen Psychiatry 1987; 44(3): 377-385.

  252. Klein DF & Gorman JM.  A model of panic and agoraphobic development.  Acta Psychiatr Scand 1987; 76 (Suppl 335): 87-95.

  253. Gorman JM, Liebowitz MR, Dillon D, Fyer AJ, Cohen BS, Klein DF.  Antipanic drug effects during lactate infusion in lactate-refractory panic patients.  Psychiatric Res 1987; 21: 205-212.

  254. Gorman JM, Davies M, Steinman R, Liebowitz MR, Fyer AJ, Coromilas J, Klein DF.  An objective marker of lactate-induced panic.  Psychiatric Res 1987; 22: 341-348.

  255. Papp LA, Klein DF, Gorman JM.  Commentary:  Hyperventilation, anxiety, and panic.  Integrative Psychiatry 1987; 5: 289-291.

  256. Fyer MR, Klein DF, Liebowitz MR, Fyer AJ, Gorman JM.  CO2 challenge of patients with panic disorder.  Am J Psychiatry 1987; 144(8): 1080-1082.

  257. McGrath PJ, Stewart JW, Markowitz J, Liebowitz MR, Gorman JM, Quitkin FM, Klein DF.  Lactate provocation of panic attacks in depressed outpatients.  Psychiatric Res 1988; 25: 41-47.

  258. Klein DF.  Cybernetics, activation, and drug effects.  Acta Psychiatrica Scandinavica 1988; 77(341): 126-137.

  259. Liebowitz MR, Quitkin FM, Stewart JW, McGrath PJ, Harrison WM, Markowitz JS, Rabkin JG, Tricamo E, Goetz DM, Klein DF.  Antidepressant specificity in atypical depression.  Arch Gen Psychiatry 1988; 45(2): 129-137.

  260. Ross DC & Klein DF.  Group matching:  Is this a research technique to be avoided?  Educational and Psychological Measurement 1988; 48: 281-295.

  261. Gorman JM, Goetz RR, Martinez J, Uy J, Ross D, Fyer AJ, Liebowitz MR, Klein DF.  Hyperventilation occurs during lactate-induced panic.  J Anxiety Disorders 1988; 2: 193-202.

  262. Wager SG & Klein DF.  Drug therapy strategies for treatment resistant depression.  Psychopharm Bull 1988; 24(1): 69-74.

  263. Klein DF & Klein HM.  The status of panic disorder.  Current Opinion in Psychiatry 1988; 1: 177-183.

  264. Gorman JM, Goetz RR, Fyer MR, King DL, Fyer AJ, Liebowitz MR, Klein DF.  The mitral valve prolapse-panic disorder connection.  Psychosomatic Medicine 1988; 50(2): 114-l22.

  265. Klein RG, Landa B, Mattes JA, Klein DF.  Methylphenidate and growth in hyperactive children: A controlled withdrawal study.  Arch Gen Psychiatry 1988; 45(12): 1127-1130.

  266. Quitkin FM, Stewart JW, McGrath PJ, Liebowitz MR, Harrison WM, Tricamo E, Klein DF, Rabkin JG, Markowitz JS, Wager SG.  Phenelzine versus imipramine in the treatment of probable atypical depression:  Defining syndrome boundaries of selective MAOI responders.  Am J Psychiatry 1988; 145(3): 306-31l.

  267. Kahn JP, Puertollano MA, Schane MD, Klein DF.  Adjunctive alprazolam for schizophrenia with panic anxiety: Clinical observation and pathogenetic implications.  Am J Psychiatry 1988; 145(6): 742-744.

  268. Stewart JW, Quitkin FM, McGrath PJ, Rabkin JG, Markowitz J, Tricamo E, Klein DF.  Social functioning in chronic depression:  Effect of six weeks of antidepressant treatment.  Psychiatric Res 1988; 25: 213-222.

  269. Papp LA, Gorman JM, Liebowitz MR, Fyer AJ, Cohen B, Klein DF.  Epinephrine infusions in patients with social phobia.  Am J Psychiatry 1988; l45(6): 733-736.

  270. Klein DF.  Rheostat and cybernetic issues.  Comments on "The Current Status of the Dopamine Hypothesis of Schizophrenia". Neuropsychopharmacology 1988; 1(3): 187-188.

  271. Liebowitz MR, Fyer AJ, Gorman JM, Campeas RB, Sandberg DP, Hollander E, Papp LA, Klein DF.  Tricyclic therapy of the DSM-III anxiety disorders:  A review with implications for further research.  J Psychiatric Res 1988; 22(1): 7-31.

  272. Fyer AJ, Liebowitz MR, Gorman JM, Campeas R, Levin A, Sandberg D, Fyer M, Hollander E, Papp LA, Goetz D, Klein DF.  Effects of clonidine on alprazolam discontinuation in panic patients:  A pilot study.  J Clin Psychopharm 1988; 8(4): 270-274.

  273. Gewirtz GR, Malaspina D, Hatterer JA, Feureisen S, Klein DF, Gorman JM.  Occult thyroid dysfunction in patients with refractory depression.  Am J Psychiatry 1988; 145(8): 1012-1014.

  274. McGrath PJ, Cooper TB, Quitkin FM, Klein DF.  Effects of imipramine and phenelzine on plasma phenylethylamine (PEA) levels.  Psychiatric Res 1988; 26: 239.

  275. Gorman JM, Fyer MR, Goetz R, Askanazi J, Liebowitz MR, Fyer AJ, Kinney J, Klein DF.  Ventilatory physiology of patients with panic disorder.  Arch Gen Psychiatry 1988; 45(1): 31-39.

  276. Mannuzza S, Fyer AJ, Martin LY, Gallops MS, Endicott J, Gorman JM, Liebowitz MR, Klein DF.  Reliability of Anxiety Assessment (I):  Diagnostic agreement.  Arch Gen Psychiatry 1989; 46(12): 1093-1101.

  277. Fyer AJ, Mannuzza S, Martin LY, Gallops MS, Endicott J, Schleyer B, Gorman JM, Liebowitz MR, Klein DF.  Reliability of Anxiety Assessment (II):  Symptom agreement.  Arch Gen Psychiatry 1989; 46(12): 1102-1110.

  278. Hollander E, Liebowitz MR, Winchel RW, Klumker A, Klein DF.  Treatment of body-dysmorphic disorder with serotonin reuptake blockers.  Am J Psychiatry 1989; 146(6): 768-770.

  279. Papp LA, Goetz R, Cole R, Klein DF, Jordan F, Liebowitz MR, Fyer AJ, Hollander E, Gorman JM.  Hypersensitivity to carbon dioxide in panic disorder.  Am J Psychiatry 1989; 146(6): 779-781.

  280. Hollander E, Liebowitz MR, Gorman JM, Cohen B, Fyer AJ, Klein DF.  Cortisol and sodium lactate-induced panic.  Arch Gen Psychiatry 1989; 46(2): 135-140.

  281. Klein DF & Klein HM.  The substantive effect of variations in panic measurement and agoraphobia definition.  J of Anxiety Disorders 1989; 3: 45-56.

  282. Gorman JM, Battista D, Goetz RR, Dillon DJ, Liebowitz MR, Fyer AJ, Kahn JP, Sandberg D, Klein DF.  A comparison of sodium bicarbonate and sodium lactate infusion in the induction of panic attacks.  Arch Gen Psychiatry 1989; 46(2): 145-150.

  283. Nunes EV, Quitkin FM, Klein DF.  Psychiatric diagnosis in cocaine abuse.  Psychiatric Res 1989; 28(1): 105-114.

  284. Quitkin FM, McGrath PJ, Stewart JW, Harrison W, Wager SG, Nunes E, Rabkin JG, Tricamo E, Markowitz J, Klein DF.  Phenelzine and imipramine in mood reactive depressives:  Further delineation of the syndrome of atypical depression.  Arch Gen Psychiatry 1989; 46(9): 787-793.

  285. Hollander E, Liebowitz MR, Cohen B, Gorman JM, Fyer AJ, Papp LA, Klein DF.  Prolactin and sodium lactate-induced panic.  Psychiatric Res 1989; 28(2): 181-191.

  286. Klein DF & Klein HM.  The utility of the panic disorder concept.  European Archives of Psychiatry & Neurological Sciences 1989; 238: 268-279.

  287. Papp LA, Martinez JM, Klein DF, Ross D, Liebowitz MR, Fyer AJ, Hollander E, Gorman JM.  Arterial blood gas changes in panic disorder and lactate-induced panic.  Psychiatric Res 1989; 28: 171-180.

  288. Goetz RR, Gorman JM, Dillon DJ, Papp LA, Hollander E, Fyer AJ, Liebowitz MR, Klein DF.  Do panic disorder patients indiscriminately endorse somatic complaints?  Psychiatric Res 1989; 29(2): 207-213.

  289. Klein DF.  Schizophrenia and bipolar affective disorders:  Likenesses and differences.  Grand Rounds presentation, Hillside Hospital, Glen Oaks, NY, February 17, 1988.  Hillside J Clin Psychiatry 1989; 11(l): 3-15.

  290. Schneier FR, Martin LY, Liebowitz MR, Gorman JM, Klein DF, Fyer AJ.  Alcohol abuse in social phobia.  J Anxiety Disorders 1989; 3: 15-23.

  291. Hollander E, Nunes E, DeCaria C, Quitkin F, Cooper T, Wager S, Klein DF.  Dopaminergic sensitivity and cocaine abuse:  Response to apomorphine.  Psychiatric Res 33:161-169, 1990.

  292. Klein DF.  Pharmacotherapy of obsessive compulsive disorder.  L'Encephale XVI:331-4, 1990.

  293. Kahn JP, Gorman JM, King DL, Fyer AJ, Liebowitz MR, Klein DF.  Cardiac left ventricular and chamber dilatation in panic disorder patients: Implications for idiopathic dilated cardiomyopathy.  Psychiatric Res 32(1):55-61, 1990.

  294. Fyer AJ, Mannuzza S, Gallops MS, Martin LY, Aaronson C, Gorman JM, Liebowitz MR, Klein DF.  Familial transmission of simple phobias and fears:  A preliminary report.  Arch Gen Psychiatry 47(3):252-256, 1990.

  295. Hollander E, DeCaria C, Schneier F, Schneier H, Liebowitz MR, Klein DF.  Fenfluramine augmentation of serotonin reuptake blockade antiobsessional treatment.  J Clin Psychiatry 51(3):119-123, 1990.

  296. Schneier F, Liebowitz MR, Fairbanks J, Hollander E, Campeas R, Klein DF.  Fluoxetine in panic disorder.  J Clin Psychopharm 10(2):119-121, 1990.

  297. Rabkin JG, McGrath PJ, Quitkin FM, Tricamo E, Stewart JW, Klein DF.  Effects of pill giving on maintenance of placebo response in patients with chronic mild depression.  Am J Psychiatry 147(12):1622-1626, 1990.

  298. Klein DF.  Psychotropic drug development:  Challenge and Promise (Editorial) Biol Psychiatry 27:1061-1064, 1990.

  299. Quitkin FM, McGrath PJ, Stewart JW, Harrison W, Tricamo E, Wager SG, Ocepek-Welikson K, Nunes E, Rabkin JG, Klein DF.  Atypical depression, panic attacks, and response to imipramine and phenelzine: A replication.  Arch Gen Psychiatry 1990; 47(10): 935-941.





  300. Hollander E, Liebowitz MR, DeCaria C, Fairbanks J, Fallon B, Klein DF.  Treatment of depersonalization with serotonin reuptake blockers.  J Clin Psychopharm 1990; 10(3): 200-203.

  301. Gorman JM, Goetz RR, Dillon D, Liebowitz MR, Fyer AJ, Davies S, Klein DF.  Sodium d-lactate infusion of panic disorder patients.  Neuropsychopharmacology 1990; 3(3): 181-189.

  302. Mannuzza S, Fyer AJ, Liebowitz MR, Klein DF.  Delineating the boundaries of social phobia:  Its relationship to panic disorder and agoraphobia.  J Anxiety Disorders 1990; 4: 41-59.

  303. Hollander E, DeCaria CM, Aronowitz B, Klein DF, Liebowitz MR, Shaffer D.  A pilot follow-up study of childhood soft-signs and the development of adult psychopathology.  J Neuropsych & Clin Neurosciences  1991; 3(2): 186-189.

  304. Hollander E, DeCaria C, Nitescu A, Cooper T, Stover B, Gully R, Klein DF, Liebowitz MR.  Noradrenergic function in obsessive compulsive disorder:  Behavioral and neuroendocrine responses to clonidine and comparison to healthy controls.  Psychiatry Res 1991; 37: 161-177.

  305. Hollander E, Mullen L, DeCaria C, Skodol A, Schneier F, Liebowitz MR, Klein DF.  Obsessive-compulsive disorder, depression, and fluoxetine.  J Clin Psychiatry 1991; 52(10): 418-422.

  306. Quitkin FM, Rabkin JG, Stewart JW, McGrath PJ, Harrison W, Ross DC, Tricamo E, Fleiss J, Markowitz J, Klein, DF.  Heterogeneity of clinical response during placebo treatment.  Am J Psychiatry  1991; 148(2): 193-196.

  307. Quitkin FM, McGrath PJ, Rabkin JG, Stewart JW, HarrisonW, Ross DC, Tricamo E, Fleiss J, Markowitz J, Klein DF.  Different types of placebo response in patients receiving antidepressants.  Am J Psychiatry 1991; 148(2): 197-203.

  308. Klein DF.  Improvement of phase III psychotropic drug trials by intensive phase II work.  Neuropsychopharmacology 1991; 4(4): 251-258.

  309. Klein DF.  Reply to commentaries:  Improvement of phase III psychotropic drug trials by intensive phase II work.  Neuropsychopharmacology 1991; 4(4): 269-271.

  310. Hollander E, DeCaria C, Nitescu A, Gulley R, Cooper TB, Gorman JM, Klein DF, Liebowitz MR.  Effects of chronic fluoxetine treatment on behavioral and neuroendocrine response to m-CPP in obsessive-compulsive disorder.  Psychiatry Res 1991; 36: 1-17.

  311. Vinar O, Klein DF, Potter WZ, Gause EM.  A survey of psychotropic medications not available in the United States.  Neuropsychopharmacology 1991; 5(4): 201-217.

  312. Quitkin FM, Harrison W, Stewart JW, McGrath PJ, Tricamo E, Ocepek-Welikson K, Rabkin JG, Wager SG, Nunes E, Klein DF.  Response to phenelzine and imipramine in placebo responders with atypical depression:  A new application of the crossover design.  Arch Gen Psychiatry 1991; 48(4): 319-323.

  313. Klein DF.  Scientific fraud and misconduct.  (Editorial)  J Clin Psychopharm 1991; 11(6): 337-338.

  314. Klein DF.  Commentary on "Psychology and Pharmacology in the Treatment of Anxiety Disorders:  Cooperation or Confrontation?" by H.C. Middleton, M.D.  J of Pharmacol 1991; 5(4): 299-300.

  315. Schneier FR, Fyer AJ, Martin LY, Ross D, Mannuzza S, Liebowitz MR, Gorman JM, Klein DF.  A comparison of phobic subtypes within panic disorder.  J Anxiety Disorders 1991; 5: 65-75.

  316. Shear MK, Fyer AJ, Ball G, Josephson S, Fitzpatrick M, Gitlin B, Frances A, Gorman J, Liebowitz M, Klein DF.  Vulnerability to sodium lactate in panic disorder patients given cognitive-behavioral therapy.  Am J Psychiatry 1991; 148(6): 795-797.

  317. Liebowitz MR, Schneier F, Campeas R, Hollander E, Hatterer J, Fyer AJ, Gorman J, Papp L, Davies S, Gully R, Klein, DF.  Phenelzine vs. atenolol in social phobia:  A placebo controlled comparison.  Arch Gen Psychiatry 1992; 49(4): 290-300.

  318. Mannuzza S, Fyer AJ, Endicott J, Gallops MS, Martin LY, Reich T, Klein DF.  An extension of the acquaintanceship procedure in family studies of mental disorder.  J Psychiatric Res 1992; 26(1): 45-57.

  319. Hollander E, DeCaria C, Nitescu A, Gully R, Suckow RF, Cooper TB, Gorman JM, Klein DF, Liebowitz MR.  Serotonergic function in obsessive compulsive disorder:  Behavioral and neuroendocrine responses to oral m-CPP and fenfluramine in patients and healthy volunteers.  Arch Gen Psychiatry 1992; 49(1): 21-28.

  320. Stewart JW, Quitkin FM, Klein DF.  The pharmacotherapy of minor depression.  Am J Psychotherapy 1992; XLVI(1): 23-36.

  321. Coplan JD, Liebowitz MR, Gorman JM, Fyer AJ, Dillon DJ, Campeas RB, Davies SO, Martinez J, Klein DF.  Noradrenergic function in panic disorder effects of intravenous clonidine pretreatment on lactate induced panic.  Biol Psychiatry 1992; 31: 135-146.

  322. Klein DF, Mannuzza S, Chapman T, Fyer AJ.  Child panic revisited.  J Am Acad of Child & Adolesc Psychiatry 1992; 31(1): 112-116.

  323. Coplan JD, Gorman JM, Klein DF.  Serotonin related functions in panic-anxiety; A critical overview.  Neuropsychopharmacology 1992; 6(3): 189-200.

  324. McGrath PJ, Stewart JW, Harrison WM, Ocepek-Welikson K, Rabkin JG, Nunes E, Wager S, Tricamo E, Quitkin FM, Klein DF.  Predictive value of symptoms of atypical depression for differential drug treatment outcome.  J Clin Psychopharm 1992; 12(3): 197-202.

  325. Stein JM, Papp LA, Klein DF, Cohen S, Simon J, Ross D, Martinez J, Gorman JM.  Exercise tolerance in panic disorder patients.  Biol Psychiatry 1992; 32: 281-287.

  326. Klein DF & Klein RG.  Methodologic issues in maintenance therapy clinical trials; A commentary.  International J of Methods in Psych Res 1992; 2(3): 107-109.

  327. Mannuzza S, Aronowitz B, Chapman T, Klein DF, Fyer AJ.  Panic disorder and suicide attempts.  J Anxiety Disorders 1992; 6: 261-274.

  328. Stein DJ, Hollander E, Anthony D, Schneier FR, Fallon BA, Liebowitz MR, Klein DF.  Serotonergic medications for sexual obsessions, sexual addictions and paraphilias.  J Clin Psychiatry 1992; 53: 267-271.

  329. Klein DF.  Commentary on "Panic disorder-old wine in new bottles" by Leo E. Hollister.  Integrative Psychiatry 1992; 8(2): 85-86.

  330. Klein DF.  Delineation of two drug-responsive anxiety syndromes. Psychopharmacologia 1964; 5: 397-408.  [Japanese version appeared in Archives of Psychiatric Diagnostic and Clinical Evaluation 1993; 4(16): 505-508.]

  331. Fyer AJ, Mannuzza S, Chapman T, Liebowitz MR, Klein DF.  A direct interview family study of social phobia.  Arch Gen Psychiatry 1993; 50(4): 286-293.

  332. Goetz RR, Klein DF, Gully DJ, Kahn J, Liebowitz MR, Fyer AJ, Gorman JM.  Panic attacks during placebo procedures in the laboratory:  Physiology and symptomatology.  Arch Gen Psychiatry 1993; 50(4): 280-285.

  333. McGrath PJ, Stewart JW, Nunes E, Ocepek-Welikson K, Rabkin JG, Quitkin FM, Klein DF.  A double-blind crossover trial of imipramine and phenelzine for outpatients with treatment-refractory depression.  Am J Psychiatry 1993; 150(1): 118-123.

  334. Klein DF & Ross DC.  Reanalysis of the National Institute of Mental Health Treatment of Depression Collaborative Research Program General Effectiveness Report.  Neuropsychopharmacology 1993; 8(3): 241-252.

  335. Klein DF.  The utility of the super-normal control group in psychiatric genetics.  Psychiatric Genetics 1993; 3(1): 17-19.

  336. Klein DF.  False suffocation alarms, spontaneous panics, and related conditions; An integrative hypothesis.  Arch Gen Psychiatry 1993; 50(4): 306-317.

  337. Quitkin FM, Stewart JW, McGrath PJ, Nunes E, Ocepek-Welikson K, Tricamo E, Rabkin J, Ross D, Klein DF.  Loss of drug effects during continuation therapy.  Am J Psychiatry 1993; 150(4): 562-565.

  338. Quitkin FM, Stewart JW, McGrath PJ, Nunes E, Ocepek-Welikson K, Tricamo E, Rabkin JG, Klein DF.  Further evidence that a placebo response to antidepressants can be identified.  Am J Psychiatry 1993; 150(4): 566-570.

  339. Chapman TF, Fyer AJ, Mannuzza S, Klein DF.  A comparison of treated and untreated simple phobia.  Am J Psychiatry 1993; 150: 816-818.

  340. Hollander E, DeCaria CM, Saoud JB, Klein DF, Liebowitz MR.  A pilot study of biological predictors of treatment outcome in obsessive-compulsive disorder.  Biol Psychiatry 1993; 33: 747-749.

  341. Klein DF.  Clinical psychopharmacologic practice:  The need for developing a research base.  Arch Gen Psychiatry 1993; 50(6): 491-494.

  342. Papp LA, Klein DF, Martinez J, Schneier F, Cole R, Liebowitz MR, Hollander E, Fyer AJ, Jordan F, Gorman JM.  Diagnostic and substance specificity of carbon-dioxide-induced panic.  Am J Psychiatry 1993; 150(2): 250-257.

  343. Papp LA, Klein DF, Gorman JM.  Carbon dioxide hypersensitivity, hyperventilation and panic disorder.  Am J Psychiatry 1993; 150(8): 1149-1157.

  344. Klein DF.  Mixed anxiety depression:  For and against.  (Proceedings of the Eighth International Thematic Meeting Paris, November 27, 1992.)  L'Encephale 1993; XIX: 493-495.

  345. Hollander E, Cohen LJ, DeCaria C, Saoud JB, Stein DF, Cooper TB, Islam MN, Liebowitz MR, Klein DF.  Timing of neuroendocrine responses and effect of m-CPP and fenfluramine plasma levels in OCD.  Biol Psychiatry 1993; 34: 407-413.

  346. Mannuzza S, Fyer AJ, Klein DF.  Assessing psychopathology.  International J of Methods in Psych Res 1993; 3: 157-165.

  347. Fallon BA, Nields JA, Parsons B, Liebowitz MR, Klein DF.  Psychiatric manifestations of Lyme Borreliosis.  J Clin Psychiatry 1993; 54(7): 263-268.

  348. Quitkin FM, Stewart JW, McGrath PJ, Tricamo E, Rabkin JG, Ocepek-Welikson K, Nunes E, Harrison W, Klein DF.  Columbia atypical depression:  A sub-group of depressives with better response to MAOI than to tricyclic antidepressants or placebo.  Br J Psychiatry 1993; 163(Suppl 21): 30-34.

  349. Klein DF.  Should the government assure scientific integrity?  Academic Medicine 1993; 68(9) Suppl: S56-S59.

  350. Fallon BF, Liebowitz MR, Salman E, Schneier F, Jusino C, Hollander E, Klein DF.  Fluoxetine for hypochondriacal patients without major depression. J Clin Psychopharm 1993; 13(6): 438-441.

  351. Gorman JM, Papp LA, Coplan J, Martinez J, Liebowitz MR, Klein DF.  The effect of acetazolamide on ventilation in panic disorder patients.  Am J Psychiatry 1993; 150(10): 1480-1484.

  352. Klein DF.  The treatment of atypical depression.  European Psychiatry 1993; 8(5): 251-255.

  353. Stein DJ, Hollander E, Chan S, DeCaria CM, Hilal S, Liebowitz MR, Klein DF.  Computed tomography and neurological soft signs in obsessive-compulsive disorder.  Psych Res 1993; 50(3): 143-150.

  354. Klein DF.  Identified placebo treatment?  Neuropsychopharmacology 1994; 10(4): 271-272.

  355. Klein DF.  The utility of guidelines and algorithms for practice.  Psychiatric Annals 1994; 24(7): 362-367.

  356. Lipsitz JD, Martin LY, Mannuzza S, Chapman TF, Liebowitz MR, Klein DF, Fyer AJ.  Childhood separation anxiety disorder in patients with adult anxiety disorders.  Am J Psychiatry 1994; 151(6): 927-929.

  357. Klein DF.  Testing the suffocation false alarm theory of panic disorder.  Anxiety 1994; 1: 1-7.

  358. Goetz RR, Klein DF, Gorman JM.  Consistencies between recalled panic and lactate induced panic.  Anxiety 1994; 1: 31-36.

  359. Chapman T, Fyer AJ, Mannuzza S, Klein DF.  Effects of informant mental disorder on psychiatric family history data.  Am J Psychiatry 1994; 151(4): 574-579.

  360. Pine DS, Weese-Mayer DE, Silvestri JM, Davies M, Whitaker A, Klein DF.  Anxiety and Congenital Central Hypoventilation Syndrome.  Am J Psychiatry 1994; 151(6): 864-870.

  361. Stein DJ, Hollander E, Klein DF.  Biological markers of depression and anxiety.  Medicographia 1994; 16(1): 18-21.

  362. Gorman JM, Papp LA, Coplan JD, Martinez JM, Lennon S, Goetz RR, Ross D, Klein DF.  Anxiogenic effects of CO2 and hyperventilation in patients with panic disorder.  Am J Psychiatry 1994; 151(4): 547-553.

  363. Liebowitz MR, Salman E, Jusino CM, Garfinkel R, Street L, Cardenas D, Silvestre J, Fyer AJ, Carrasco JL, Davies S, Guarnaccia P, Klein DF.  Ataque de nervios and panic disorder.  Am J Psychiatry 1994; 151(6): 871-875.

  364. Klein DF.  Commentary:  Pregnancy and panic disorder.  J Clin Psychiatry 1994; 55(7): 293-294.

  365. Mannuzza S, Schneier FR, Chapman TF, Liebowitz MR, Klein DF, Fyer AJ.  Generalized social phobia:  Reliability and validity.  Arch Gen Psychiatry 1995; 52: 230-237.

  366. Papp LA, Martinez JM, Klein DF, Coplan J, Gorman JM.  Rebreathing tests in panic disorder.  Biol Psychiatry 1995; 38(4): 240-245.

  367. Nunes EV, McGrath PJ, Quitkin FM, Ocepek-Welikson K, Stewart JW, Koenig T, Wager S, Klein DF.  Imipramine treatment of cocaine abuse: Possible boundaries of efficacy.  Drug and Alcohol Dependence 1995; 39: 185-195.

  368. Fyer AJ, Mannuzza S, Chapman TF, Martin LY, Klein DF.  Specificity in familial aggregation of phobic disorders.  Arch Gen Psychiatry 1995; 52(7): 564-573.

  369. Klein DF, Skrobala A, Garfinkel RS.  Preliminary look at the effects of pregnancy on the course of panic disorder.  Anxiety 1995; 1(5): 227-232.

  370. Mannuzza S, Chapman TF, Klein DF, Fyer AJ.  Familial transmission of panic disorder: Effect of major depression comorbidity.   Anxiety 1994/1995; 1: 180-185.

  371. Klein DF.  Improving medication and legislation by controlled experimentation.  Psychiatric Annals 1995; 25(1): 67-69.

  372. Klein DF.  Psychopharmacological practice and health reform.  Psychiatric Annals 1995; 25(2): 79-83.

  373. Klein DF.  Response to critique of suffocation alarm theory.  Anxiety 1995; 1(3): 145-148.

  374. Klein DF.  Treatment of panic disorder, agoraphobia and social phobia.  Clinical Neuropharmacology 1995; 18 (Suppl 2): S45-S51.

  375. Resschke AH, Mannuzza S, Chapman TF, Lipsitz JD, Liebowitz MR, Gorman JM, Klein DF, Fyer AJ.  Sodium lactate response and familial risk for panic disorder.  Am J Psychiatry 1995; 152(2): 277-279.

  376. Klein DF.  Response to Rothman and Michels on placebo-controlled clinical trials.  Psychiatric Annals 1995; 25(7): 401-403.377.   

  377. Marshall RD & Klein DF.  Pharmacotherapy in the treatment of posttraumatic stress disorder.  Psychiatric Annals 1995; 25(10): 588-597.

  378. Papp LP, Welkowitz LA, Martinez JM, Klein DF, Browne S, Gorman JM.  Instructional set does not alter outcome of respiratory challenges in panic disorder.  Biological Psychiatry 1995; 38(12): 826-830.

  379. Klein DF.  What’s new in DSM-IV?  Psychiatric Annals 1995; 25(8): 461-474.

  380. Klein DF.  Counterevidence from psychopharmacology, psychopathology, and psychobiology.  Behav Brain Sci 1995; 18(2): 302-303.

  381. Klein DF.  Foreword: Controversies and conventions in panic disorder: questions and answers in recognition and treatment.  European Psychiatry 1995; 10 (Suppl 2): 55S.

  382. Klein DF.  Recognising panic disorder.  European Psychiatry 1995; 10 (Suppl 2): 61S-63S.

  383. Liebowitz MR, Coplan JD, Martinez J, Fyer AJ, Dillon DJ, Campeas RB, Davies SO, Gorman JM, Klein DF.  Effects of intravenous diazepam pretreatment on lactate-induced panic.  Psychiatry Research 1995; 58: 127-138.

  384. Glick ID, Lecrubier Y, Montgomery SA, Vinar O, Klein DF.  Efficacious and safe psychotropics not available in the United States.  Psychiatric Annals 1996; 26: 354-361.385.   

  385. Martinez JM, Papp LA, Anderson DE, Mueller CM, Klein DF, Coplan JD, Gorman JM.  Ambulatory monitoring of respiration in anxiety.  Anxiety 1996; 2: 296-302.

  386. Quitkin FM, McGrath PJ, Stewart JW, Ocepek-Welikson K, Taylor BP, Nunes E, Deliyannides D, Agosti V, Donovan SJ, Petkova E, Klein DF.  Chronological milestones to guide drug change: When should clinicians switch antidepressants?  Arch Gen Psychiatry 1996; 53(9): 785-792.

  387. Schwartz GE, Goetz RR, Klein DF, Endicott J, Gorman JM.  Tidal volume of respiration and "sighing" as indicators of breathing irregularities in panic disorder patients.  Anxiety 1996; 2/3: 145-148.

  388. Quitkin FM, McGrath PJ, Stewart JW, Taylor BP, Klein DF.  Can the effects of antidepressants be observed in the first two weeks of treatment?  Neuropsychopharmacology 1996; 15(4): 390-394.

  389. Fyer AJ, Mannuzza S, Chapman TF, Lipsitz J, Martin LY, Klein DF.  Panic disorder and social phobia: Effects of comorbidity on familial transmission.  Anxiety 1996; 2: 173-178.

  390. Klein DF.  Preventing hung juries about therapy studies.  J Consulting and Clinical Psychology 1996; 64(1): 81-87.

  391. Goetz RR, Klein DF, Gorman JM.  Symptoms essential to the experience of sodium lactate-induced panic.  Neuropsychopharmacology 1996; 14(5): 355-366.

  392. Klein DF. Discussion of "Methodological Controversies in the Treatment of Panic Disorder" by McNally.  Behaviour Research and Therapy 1996; 34(11/12): 849-853.

  393. Klein DF. Critiquing McNally’s reply.  Behaviour Research and Therapy 1996; 34(11/12): 859-863.

  394. Klein DF. Comments on "Integrity and Misconduct in Research".  Psychiatric Annals 1996; 26(10): 669-675.

  395. Klein DF.  Panic disorder and agoraphobia: Hypothesis hothouse.  J Clin Psychiatry 1996; 57(Suppl 6): 21-27.

  396. Papp LA, Martinez JM, Klein DF, Coplan JD, Norman RG, Cole R, de Jesus MJ, Ross D, Goetz R, Gorman JM.  Respiratory psychophysiology of panic disorder: Three respiratory challenges in 98 subjects.  Am J Psychiatry 1997; 154(11): 1557-1565.

  397. Coplan JD, Papp LA, Pine D, Martinez J, Cooper T, Rosenblum LA, Klein DF, Gorman JM.  Clinical improvement with fluoxetine therapy and noradrenergic function in patients with panic disorder.  Arch Gen Psychiatry 1997; 54(7): 643-648.

  398. Donovan SJ, Susser ES, Nunes EV, Stewart JW, Quitkin FM, Klein DF.  Divalproex treatment of disruptive adolescents: A report of 10 cases.  J Clin Psychiatry 1997; 58(1): 12-15.

  399. Klein DF & Smith LB.  A psychotherapeutic context for pharmacotherapy trials is promising, but manualization is not.  Arch Gen Psychiatry 1997; 54(10): 929-930.





  400. Papp LA, Schneier FR, Fyer AJ, Liebowitz MR, Gorman JM, Coplan JD, Saoud J, Campeas R, Fallon B, Jusino C, Klein DF.  Clomipramine treatment of panic disorder: Pro’s and con’s.  J Clin Psychiatry 1997; 58(10): 423-425.

  401. Gorman JM, Browne ST, Papp LA, Martinez J, Welkowitz L, Coplan JD, Goetz RR, Kent J, Klein DF.  Effect of antipanic treatment on response to carbon dioxide.  Biol Psychiatry 1997; 42: 982-991

  402. Klein DF.  Control groups in pharmacotherapy and psychotherapy evaluations.  Prevention and Treatment.  http://journals.apa.org/treatment/vol1/97_a1.html, posted 9/22/97.

  403. Fallon BA, Liebowitz MR, Campeas R, Schneier FR, Marshall R, Davies S, Goetz D, Klein DF.  Intravenous clomipramine for obsessive compulsive disorder refractory to oral clomipramine: A placebo controlled study.  Arch Gen Psychiatry 1998; 55(10): 918-924.

  404. Heimberg RG, Liebowitz MR, Schneier FR, Hope DA, Holt CS, Welkowitz LA, Juster HR, Campeas R, Bruch MA, Cloitre M, Fallon B, Klein DF.  Cognitive-behavioral group therapy vs phenelzine therapy for social phobia: 12-week outcome.  Arch Gen Psychiatry 1998; 55(12): 1133-1141.

  405. Stewart JW, Garfinkel R, Nunes EV, Donovan S,  Klein DF.  Atypical features and treatment response in the National Institute of Mental Health Treatment of Depression Collaborative Research Program.  J Clin Psychopharm 1998; 18(6): 429-434.

  406. Klein RG, Pine DS, Klein DF.  Mania is mistaken for ADHD in prepubertal children.  A debate (against).   J Am Acad Child Adolesc Psychiatry 1998; 37(10): 1093-1096, 1098-1099.

  407. Quitkin FM, McGrath PJ, Stewart JW, Ocepek-Welikson K, Taylor BP, Nunes E, Deliyannides D, Agosti V, Donovan SJ, Ross D, Petkova E, Klein DF.  Placebo run-in period in studies of depressive disorders; Clinical, heuristic and research implications.   Br J Psychiatry 1998; 173: 242-248.

  408. Salman E, Liebowitz MR, Guarnaccia PJ, Jusino CM, Garfinkel R, Street L, Cardenas DL, Silvestre J, Fyer AJ, Carrasco JL, Davies SO, Klein DF.   Subtypes of ataques de nervios: The influence of coexisting psychiatric diagnosis.  Culture, Medicine and Psychiatry 1998; 22(2): 231-244.

  409. Simpson HB, Schneier FR, Campeas RB, Marshall RD, Fallon BA, Davies S, Klein DF, Liebowitz MR.  Imipramine in the treatment of social phobia.  J Clin Psychopharmacology 1998; 18(2): 132-135.

  410. Klein DF.  Editorial:  The significance of panic in general medicine.  J Psychosomatic Research 1998; 44(1): 17-19.

  411. Pine DS, Coplan JD, Papp LA, Klein RG, Martinez JM, Kovalenko P, Tancer N, Moreau D, Dummit ES, Shaffer D, Klein DF, Gorman JM.  Ventilatory physiology of children and adolescents with anxiety disorders.  Arch Gen Psychiatry 1998; 55(2): 123-129.

  412. Coplan JD, Goetz R, Klein DF, Papp LA, Fyer AJ, Liebowitz MR, Davies SO, Gorman JM.  Plasma cortisol concentrations preceding lactate-induced panic; Psychological, biochemical, and physiological correlates.  Arch Gen Psychiatry 1998; 55(2): 130-136.

  413. Klein DF.  Commentary: The treatment of panic.  Psychopharm Bull 1998; 34(2): 197.

  414. Martinez JM, Coplan JD, Browne ST, Goetz R, Welkowitz LA, Papp LA, Klein DF, Gorman JM.  Hemodynamic response to respiratory challenges in panic disorder.  J Psychosom Res 1998; 44(1): 153-161.

  415. Klein DF.  Listening to meta-analysis but hearing bias.  Prevention and Treatment.  http://journals.apa.org/prevention/volume1/pre0010008r.html, posted 6/26/98.

  416. Klein DF.  Reply to Kirsch’s rejoinder regarding antidepressant meta-analysis.  Prevention and Treatment.   posted 11/20/98.

  417. Knowles JA, Fyer AJ, Vieland VJ, Weissman MM, Hodge SE, Heiman GA, Haghighi F, de Jesus GM, Rassnick H, Preud’homme-Rivelli X, Austin T, Cunjak J, Mick S, Fine LD, Woodley KA, Das K, Maier W, Adams PB, Freimer NB, Klein DF, Gilliam TC.  Results of a genome-wide genetic screen for panic disorder.  American Journal of Medical Genetics (Neuropsychiatric Genetics) 1998; 81: 130-147.

  418. Klein DF.  Panic and phobic anxiety: Phenotypes, endophenotypes, and genotypes.  Am J Psychiatry 1998; 155(9): 1147-1149.

  419. Klein DF.  Evidence for the Validity of the Concept of Panic Disorder.  European Neuropsychopharmacology 1998; 8(Suppl 2): S57-60.

  420. Lipsitz JD, Mannuzza S, Klein DF, Ross DC, Fyer AJ.  Specific phobia 10-16 years after treatment.  Depression & Anxiety 1999; 10: 105-111.

  421. Klein DF.  Harmful dysfunction, disorder, disease, illness, and evolution.  J Abnorm Psychol 1999; 108(3): 421-429.

  422. Klein DF.  Dealing with the effects of therapy allegiances.  Clin Psychol: Sci & Practice 1999; 6: 124-126.

  423. Hamilton SP, Heiman GA, Haghigi FG, Mick S, Klein DF, Hodge SE, Weissman MM, Fyer AJ, Knowles JA.  Lack of genetic linkage or association between a functional serotonin transporter polymorphism and panic disorder.  Psychiatric Genetics 1999; 9: 1-6.

  424. Klein DF & Smith LB.  Organizational requirements for effective clinical effectiveness studies.  Prevention and Treatment. posted March 21, 1999.

  425. Klein DF.  Commentary:  The report by the Institute of Medicine and Postmarketing Surveillance.  Arch Gen Psychiatry 1999; 56(4): 353-354.

  426. Coplan JD, Tamir H, Calaprice D, de Jesus MJ, de la Nuez M, Pine D, Papp LA, Klein DF, Gorman JM.  Plasma anti-serotonin and serotonin anti-idiotypic antibodies are elevated in panic disorder. Neuropsychopharmacology 1999; 20(4): 386-391.

  427. Sinha SS, Coplan JD, Pine DS, Martinez JA, Klein DF, Gorman JM.  Panic induced by carbon dioxide inhalation and lack of hypothalamic-pituitary-adrenal axis activation.  Psychiatry Res 1999; 86: 93-98.428.   

  428. Breslau N & Klein DF.  Smoking and panic attacks: An epidemiologic investigation.  Arch Gen Psychiatry 1999; 56(12): 1141-1147.

  429. Sinha SS, Goetz R, Klein DF.  Non-fearful panic induction in normals with naloxone pretreatment of lactate infusion.  Psychiatry Research.  (in press)

  430. Liebowitz MR, Heimberg RG, Schneier FR, Hope DA, Davies S, Holt CS, Goetz D, Juster HR, Lin S-H, Bruch MA, Marshall, RD, Klein DF.  Cognitive-behavioral group therapy versus phenelzine in social phobia: Long term outcome.  Depression and Anxiety 1999; 10: 89-98.

  431. Hamilton SP, Haghighi F, Heiman GA, Klein DF, Hodge SE, Fyer AJ, Weissman MW, Knowles JA.  Investigation of dopamine receptor (DRD4) and dopamine transporter (DAT) polymorphisms for genetic linkage or association to panic disorder.  Am J of Med Gen 2000; 96(3): 324-30.

  432. Petkova E, Quitkin FM, McGrath P, Stewart J, Klein DF.  A method to quantify rater bias in antidepressant trials.  Neuropsychopharmacology 2000; 22(6): 559-565.

  433. Pine DS, Klein RG, Coplan JD, Papp LA, Hoven CW, Martinez J, Kovalenko P, Mandell DJ, Moreau D, Klein DF, Gorman JM.  Differential carbon dioxide sensitivity in childhood anxiety disorders and non-ill comparison group.  Arch Gen Psychiatry 2000; 57(10): 960-967.

  434. Olfson M, Guardino M, Struening E, Schneier FR, Klein DF.  Barriers to the treatment of social anxiety.  Am J Psychiatry 2000; 157(4): 521-527.

  435. Quitkin F, Rabkin JG, Gerald J, Davis JM, Klein DF.  Validity of clinical trials of antidepressants.  Am J Psychiatry 2000; 157(3): 327-337.

  436. Klein DF.  Flawed meta-analyses comparing psychotherapy with pharmacotherapy.  Am J Psychiatry 2000; 157(8): 1204-1211.

  437. McGrath PJ, Stewart JW, Janal MN, Petkova E, Quitkin FM, Klein DF.  A placebo- controlled study of fluoxetine versus imipramine in the acute treatment of atypical depression.  Am J Psychiatry 2000; 157(3): 344-350.

  438. Johnson JG, Cohen P, Pine DS, Klein DF, Kasen S, Brook JS.  Association between cigarette smoking and anxiety disorders during adolescence and early adulthood.  JAMA 2000; 284(19): 2348-2351.

  439. Donovan SJ, Stewart JW, Nunes EV, Quitkin FM, Parides M, Daniel W, Susser E, Klein DF.  Divalproex treatment for youth with explosive temper and mood lability: A double-blind, placebo-controlled crossover design.  Am J Psychiatry 2000; 157(5): 818-820.

  440. Quitkin FM & Klein DF.  What conditions are necessary to assess antidepressant efficacy?   Arch Gen Psychiatry 2000; 57(4): 323-324.

  441. Hamilton SP, Slager S, Helleby L, Heiman GA, Klein DF, Hodge SE, Weissman ME, Fyer AJ, Knowles JA.  No association or linkage between polymorphisms in the genes encoding cholecystokinin and the cholecystokinin B receptor and panic disorder.  Molecular Psychiatry 2001; 6: 59-65.

  442. Goetz RR, Klein DF, Papp LA, Martinez JM, Gorman JM.  Acute panic inventory symptoms during CO2 inhalation and room-air hyperventilation among panic disorder patients and normal controls.  Depression and Anxiety  2001; 14(2): 123-136.

  443. Kent JM, Papp LA, Martinez JM, Browne ST, Coplan JD, Klein DF, Gorman JM.  Specificity of panic response to CO2 inhalation in panic disorder: A comparison with major depression and premenstrual dysphoric disorder.  Am J Psychiatry 2001; 158(1): 58-67.444. 

      
  444. Martinez JM, Coplan JD, Browne ST, Papp LA, Fyer AJ, Klein DF, Gorman JM.  Respiratory variability in panic disorder.  Depression and Anxiety 2001; 14: 232-237.

  445. Preter M, Martinez J, Ross DC, Klein DF.  Hematologic alterations and CO2 hypersensitivity in male panic disorder patients and normal controls:  Similarities to high altitude hypoxia and chronic lung disease.  Depression and Anxiety 2001; 14(2): 153-154.

  446. Glick ID, Janowsky DS, Zisook S, Lydiard RB, Oesterheld JR, Ward NG, Ellison J, Halper J, Shear MK, Doraiswamy PM, Preven DW, Ross P, Klein DF.  How should we teach psychopharmacology to residents?  Results of the initial experience with the ASCP Model Curriculum.  Academic Psychiatry 2001; 25(2): 90-97.

  447. Klein DF, Lipsitz J, Fyer A, Paternitti A.  Emetophobia:  Preliminary Results of an Internet Survey.  Depression and Anxiety 2001; 14(2): 149-152.

  448. Sheikh JI, Leskin GA, Klein DF.  Gender differences in Panic Disorder:  Findings from the National Comorbidity Survey.  Am J Psychiatry 2002; 159: 55-58.

  449. Klein DF, Thase M, Endicott J, Adler L, Glick I, Kalali A, Levanter S, Mattes J, Ross P, Bystritsky A.  Improving clinical trials: American Society of Clinical Psychopharmacology Recommendations.  Arch Gen Psychiatry 2002; 59: 272-278.

  450. Hamilton S, Slager S, Heiman G, Deng Z, Klein DF, Hodge S, Weissman M, Fyer A, Knowles J.  Evidence for a Susceptibility Locus for Panic Disorder near the Catechol-O-Methyltransferase Gene on Chromosome 22.  Biological Psychiatry 2002; 51: 591-601.

  451. Marshall R, Blanco C, Printz D, Liebowitz M, Klein DF, Coplan J.  A Pilot Study of Noradrenergic and HPA axis Functioning in PTSD vs. Panic Disorder.  Psychiatric Research 2002; 110(3): 219-30.

  452. Mannuza S, Klein R, Moulton J, Scarfone N, Malloy P, Vosburg S, Klein D.  Anxiety sensitivity among children of parents with anxiety disorders:  a controlled high-risk study.  Journal of Anxiety Disorders 2002; 16: 135-148.

  453. Mannuza S, Klein R, Klein R, Bessler A, Shrout P.  Accuracy of adult recall of childhood attention deficit hyperactivity disorder.  American Journal of Psychiatry 2002; 159: 1882-1888.

  454. Ross D, Quitkin F, Klein D.  A Typological Model for Estimation of Drug and Placebo Effects in Depression.  Journal of Clinical Psychopharmacology 2002; 22: 414-418.

  455. Slattery M, Klein DF, Mannuzza S, Moulton J, Pine D, Klein RG.  Relationship Between Separation Anxiety Disorder, Parental Panic Disorder, and Atopic Disorders in Children: A Controlled High-Risk Study.  J Am Acad Adolesc Psychiatry 2002; 41(8): 947-954.

  456. Quitkin F, Stewart J, McGrath P, Taylor B, Tisminetzky M, Petkova E, Chen Y, Ma G, Klein D.  Are there differences between women’s and men’s antidepressant responses?  Am J Psychiatry  2002; 159: 1848-1854.

  457. Klein D.  Historical Aspects of Anxiety.  Dialogues in Clinical Neuroscience 2002; 4: 295-303.

  458. Klein D.  Commentary:  Identifying Adaptation by Dysfunction.  Behavioral and Brain Science 2002; 25(4): 521-522.

  459. Klein D.  Editorial:  Fostering Treatment Advances.  Journal of Clinical Psychopharmacology 2002; 22: 541-2.
  460. Quitkin F, Petkova E, McGrath P, Taylor B, Beasley C, Stewart J, Amsterdam J, Fava M, Rosenbaum J, Reimherr F, Fawcett J, Chen Y, Klein D.  When should a trial of fluoxetine for major depression be declared failed?  American Journal of Psychiatry 2003; 160(4): 734-740.

  461. Klein D.  Peer Commentary:  Initiating treatment evaluations.  Archives of Sexual Behavior October 2003; 32(5): 442-443.

  462. Donovan SJ, Nunes EV, Stewart JW, Quitkin FM, Jensen PS, Klein DF.  “Outer-Directed Irritability”: a distinct mood syndrome in explosive youth with a disruptive behavior disorder?  Journal of Clinical Psychiatry 2003; 64: 698-701.

  463. Hamilton S, Slager S, de Leon A, Heiman G, Klein DF, Hodge S, Weissman M, Fyer A, Knowles J.  Evidence for genetic linkage between a polymorphism in the adenosine 2A receptor (ADORA2A) and Panic Disorder.  Neuropsychopharmacology 2004; 29: 558-565.

  464. Hamilton S, Slager S, Mayo D, Heiman G, Klein D, Hodge S, Fyer A, Myrna W, Knowles J.  Investigation of polymorphisms in the CREM gene in Panic Disorder.  American Journal of Medical Genetics 2004; 126B(1): 111-115.

  465. Klein DF & Stewart JW.  Genes and Environment:  Nosology and Psychiatry.     Neurotoxicity Research 2004; 6(1): 11-5.

  466. Quitkin FM, McGrath PJ, Stewart JW, Deliyannides D, Taylor BP, Davies CA, Klein DF.  Remission rates with 3 consecutive antidepressant trials:  effectiveness for depressed outpatients.  Journal of Clinical Psychiatry 2005; 66(6): 670-676.

  467. Klein DF.  Commentary:  Comments on Psychiatric Education.  Academic Psychiatry 2005; 29(2): 128-133.

  468. Glick ID, Klein DF, Nasrallah H, Schatzberg AS, Wang P, Zisook S, Moutier C. Can the clinical practice of psychopharmacology be improved by good teaching?  Submitted Neuropsychopharmacology May 2005.

  469. Stewart JW, Quitkin FM, McGrath PJ, Klein DF.  Defining the boundaries of atypical depression: Evidence from the HPA axis supports course of illness distinctions.  Journal of Affective Disorders 2005; 86(2-3): 161-7.

  470. Quitkin FM, McGrath PJ, Stewart JW, Deliyannides D, Taylor B ,Davies CA, Klein DF. Remission rates with 3 consecutive antidepressant trials: effectiveness for depressed outpatients. J Clin Psychiatry. 2005 Jun;66(6):670-6.

  471. Klein DF. The flawed basis for FDA post-marketing safety decisions: the example of anti-depressants and children. Neuropsychopharmacology. 2006 Apr;31(4):689-99.

  472. Fyer AJ, Hamilton SP, Durner M, Haghighi F, Heiman GA, Costa R, Evgrafov O, Adams P, de Leon AB, Taveras N, Klein DF, Hodge SE, Weissman MM, Knowles JA. A third-pass genome scan in panic disorder: evidence for multiple susceptibility loci. Biol Psychiatry. 2006 Aug 15;60(4):388-401.

  473. Goodwin RD, Lipsitz JD, Chapman TF, Mannuzza S, Klein DF, Fyer AJ. Alcohol use disorders in relatives of patients with panic disorder. Compr Psychiatry. 2006 Mar-Apr;47(2):88-90.
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