BIOPHYSICS and BIOPHYSICAL CHEMISTRY at COLUMBIA UNIVERSITY

Calcium is arguably the smallest of the most important and ubiquitous cell signaling molecules that travel in and out of cells via specialized protein channels or pumps. The image shows the TRPV6 channel that selectively ransports calcium ions (green spheres) through epithelial cell membranes and is implicated in development and progression of numerous forms of cancer. The first crystal structure of TRPV6, solved at 3.25 Angstrom resolution, uncovers the atomic bases of calcium-selective permeation in tetrameric ion channels and provides a blueprint for future drug design.  Courtesy of Alexander Sobolevsky.


CORE COURSES:

ELECTIVE COURSES:

  •  Advanced Seminar in Molecular and Cellular Neurobiology
  • W4070: Biology and Physics of Single Molecules
  • G4312:   Chemical Biology
  • G4015:  Computational Biology
  • GR6400:   Cryoelectron Microscopy
  •  Molecular Systems Biology
  •  Molecular Modeling
  • GR6222:  Quantum Chemistry
  • GU4230: Statistical Thermodynamics
  • G6270:   NMR Spectroscopy
  • G6275:   Diffraction Analysis
  • G6045:   Membrane Receptors

TRAINING PROGRAM:

The Training Program in Molecular Biophysics at Columbia University is supported by National Institutes of Health Grant Number T32GM008281.

FACULTY AND RESEARCH:


 

APPLICATION THROUGH PARTICIPATING DEPARTMENTS:

Department of Biochemistry and Molecular Biophysics

Department of Biological Sciences

Department of Chemistry

Department of Pharmacology

Department of Physiology and Cellular Biophysics

Students interested in entering this Ph. D. program should apply to one of the participating departments and indicate an interest in the subfield of biophysics.  Students entering this program will have the opportunity to perform rotations or doctoral research with any member of the biophysics faculty.


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