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Publications
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Selected Recent Publications
Boggon TJ, Murray J, Chappuis-Flament S, Wong E, Gumbiner BM, and Shapiro L. C-Cadherin Ectodomain Structure and Implications for Cell Adhesion Mechanisms. Science (2002) 296, 1308-1313.
Santagata, S., Gomez, C., Shan, W.S., Baird, C.L., Zhao, J., Myszka, D., and Shapiro, L. G Protein Signaling through Tubby ProteinsScience (2001) 292, 2041-2050.
Shapiro, L. and Colman, D.R The diversity of cadherins and implications for a synaptic adhesive code in the CNS. (1999) Neuron 23, 427-430.
Selected Publications
Boggon TJ, Murray J, Chappuis-Flament S, Wong E, Gumbiner BM, and Shapiro L. C-Cadherin Ectodomain Structure and Implications for Cell Adhesion Mechanisms. Science (2002) 296, 1308-1313.
Gogos, A. and Shapiro, L. Large Conformational Changes in the Catalytic Cycle of Glutathione Synthase, Structure (2002) 10, 1669-1676.
Boggon, T.J., Murray, J., Chapuis-Flament, S., and Shapiro, L. Crystal Structure of the C-cacdherin Ectodomain and Implications for the Mechanism of Adhesion. (2002) Science, in press.
Santagata, S., Gomez, C., Shan, W.S., Baird, C.L., Zhao, J., Myszka, D., and Shapiro, L. G. Protein Signaling through Tubby Proteins. (2001) Science, 292, 2041-2050.
Phillips, G.R., Huang,J.K., Wang,Y. Tanaka, H., Shapiro, L., Zhang, W., Shan, W., Arndt, K., Frank, M., Gordon, R.E., Gawinowicz, M.A., Zhao, Y., and Colman, D.R. The presynaptic particle web: Ultrastructure, composition, dissolution and reconstitution.(2001) Neuron, 32, 63-77.
Benson, D.L., Schnapp, L.M., Shapiro, L., and Huntley, G.W. Making memories stick: cell adhesion molecules in synaptic plasticity. (2000) Trends Cell Biol., 10, 473-482.
Boggon, T.J. and Shapiro, L. Screening for phasing atoms in protein crystallography. (2000) Structure 8, R143-149.
Shapiro, L. and Harris, T. Finding function through structural genomics. (2000) Current Opinion in Biotechnology, 11, 31-35.
Shan, W.-S., Colman, D.R., and Shapiro, L. Functional cis heterodimers of N- and R-cadherins. (2000) Journal of Cell Biology, 148, 579-590.
Tanaka, H., Shan, W., Phillips, G.R., Arndt, K., Bozdagi, O., Shapiro, L., Huntley, G.W., Benson, D.L., and Colman, D.R. Molecular modification of N-cadherin in response to synaptic activity. (2000) Neuron, 25, 93-107.
Boggon, T.J., Shan, W.-S., Santagata, S. Myers, S.C., and Shapiro, L. Implication of tubby proteins as transcription factors by structure-based functional analysis. (1999) Science, 286, 2119-2125.
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