Research Faculty

R. Theodore Smith, M.D., Ph.D R. Theodore Smith, M.D., Ph.D.
Professor of Clinical Ophthalmology (in Biomedical Engineering)
Director, Retinal Image Analysis Laboratory Principal Clinical Investigator, Columbia Macular Genetics Study
Mail Address:

Columbia University
E.S. Harkness Eye Institute
635 West 165th Street Box 12
New York, NY 10032

Office Location:

Columbia University
E.S. Harkness Eye Institute
160 Fort Washington Avenue
Room 509C
New York, NY 10032

Office: 212-342-1849
Lab: 212-305-5664
Fax: 212-342-3187
Email: rts1@columbia.edu

Research Areas

The Retinal Image Analysis Laboratory, in collaboration with Biomedical Engineering, has developed automated techniques and user-interactive computer software to streamline the processing and analysis of images used in the study of retinal degenerative diseases, such as age-related macular degeneration, retinitis pigmentosa, and Stargardt disease. Because biopsy of living retinas is hazardous, retinal images are a key component of individual patient treatment and research. We use our image analysis techniques to examine large data sets – such as the ongoing Columbia Macular Genetics Study, which includes data on more than 4,000 patients – and to discover new insights about the genetics, risk factors, progression, and staging of retinal disease. Retinal degenerative disease takes a terrible toll on members of our population of all ages, but our research will lead to more treatment options and a reduction of vision loss for these patients.

Selected Awards and Honors

Phi Beta Kappa, Rice University

Summa Cum Laude, Rice University

Marshall Scholar, Warwick University, England

National Science Foundation Fellow

Alpha Omega Alpha, Albert Einstein College of Medicine (President, Einstein chapter)

“Best Poster Presentation” Award at American Academy of Ophthalmology 2009 Annual Meeting

24 years of annual grants from the New York Community Trust for research on retinal diseases

5-year R01 NIH grant for image analysis of age-related macular degeneration

3-year R01 NIH grant for the study of absolute fundus autofluorescence in retinal degenerations

NIH instrument grant for the study of retinal degenerations


Research Summary

Staff

Selected Recent Publications