Click on the following links to access Dr. Pile-Spellman’s most recent peer-reviewed publications (selected from over 100 publications)

 

  1. Feng L, Kienitz BA, Matsumoto C, Bruce J, Sisti M, Duong H, Pile-Spellman J.  Feasibility of using hyperosmolar mannitol as a liquid tumor embolization agent.  AJNR Am J Neuroradiol.  2005 Jun-Jul;26(6):1405-12.

 

  1. Feng L, Matsumoto C, Schwartz A, Schmidt AM, Stern DM, Pile-Spellman J.  Chronic vascular inflammation in patients with type 2 diabetes: endothelial biopsy and RT-PCR analysis.  Diabetes Care.  2005 Feb;28(2):379-84.

 

  1. Feng L, Dumoulin CL, Dashnaw S, Darrow RD, Guhde R, Delapaz RL, Bishop PL, Pile-Spellman J.  Transfemoral catheterization of carotid arteries with real-time MR imaging guidance in pigs.  Radiology.  2005 Feb;234(2):551-7.

 

  1. Feng L, Dumoulin CL, Dashnaw S, Darrow RD, Delapaz RL, Bishop PL, Pile-Spellman J.  Feasibility of stent placement in carotid arteries with real-time MR imaging guidance in pigs.  Radiology. 2005 Feb;234(2):558-62.

 

  1. Gobin YP, Starkman S, Duckwiler GR, Grobelny T, Kidwell CS, Jahan R, Pile-Spellman J, Segal A, Vinuela F, Saver JL.  MERCI 1: a phase 1 study of Mechanical Embolus Removal in Cerebral Ischemia.  Stroke.  2004 Dec;35(12):2848-54.

 

  1. Festa JR, Lazar RM, Marshall RS, Pile-Spellman J, Chong JY, Duong H.  Dural arteriovenous fistula presents like an ischemic stroke.  Cogn Behav Neurol.  2004 Mar;17(1):50-3.

 

  1. Joshi S, Meyers PM, Pile-Spellman J, Wang M, Sahlein DH.  Intracarotid verapamil decreases both proximal and distal human cerebrovascular resistance.  Anesthesiology.  2004 Apr;100(4):774-81.

 

  1. Khaw AV, Mohr JP, Sciacca RR, Schumacher HC, Hartmann A, Pile-Spellman J, Mast H, Stapf C.  Association of infratentorial brain arteriovenous malformations with hemorrhage at initial presentation.  Stroke.  2004 Mar;35(3):660-3.

 

  1. Gupta R, Schumacher HC, Mangla S, Meyers PM, Duong H, Khandji AG, Marshall RS, Mohr JP, Pile-Spellman J.  Urgent endovascular revascularization for symptomatic intracranial atherosclerotic stenosis.  Neurology.  2003 Dec 23:61(12):1729-35.

 

  1. Stapf C, Khaw AV, Sciacca RR, Hofmeister C, Schumacher HC, Pile-Spellman J, Mast H, Mohr JP, Hartmann A.  Effect of age on clinical and morphological characteristics in patients with brain arteriovenous malformation.  Stroke.  2003 Nov;34(11):2664-9.

 

  1. Schumacher HC, Meyers PM, Yavagal DR, Harel NY, Elkind MS, Mohr JP, Pile-Spellman J.  Endovascular mechanical thrombectomy of an occluded superior division branch of the left MCA for acute cardioembolic stroke.  Cardiovasc Intervent Radiol.  2003 May-June;26(3):305-8.

 

  1. Schumacher HC, Dumoulin CL Feng L, Mangla S, Meyers PM, Hirsch J, Mohr JP, DeLaPaz RL, Pile-Spellman J. Real-time magnetic resonance imaging for interventional neuroradiological procedures. Surg Technol Int. 2003;11:183-96.

 

  1. Fitzsimmons BF, Marshall RS, Pile-Spellman J, Lazar RM. Neurobehavioral differences in superselective Wada testing with amobarbital versus lidocaine. AJNR Am J Neuroradiol. 2003 Aug;24(7):1456-60.

 

  1. Schumacher HC, Tanji K, Mangla S, Meyers P, Pile-Spellman J, Hays AP, Mohr JP. Histopathological evaluation of middle cerebral artery after percutaneous intracranial transluminal angioplasty. Stroke. 2003 Sep;34(9):e170-3.

 

  1. Stapf C, Mast H, Sciacca RR, Berenstein A, Nelson PK, Gobin YP, Pile-Spellman J, Mohr JP; New York Islands AVM Study Collaborators.  The New York Islands AVM Study: design, study progress, and initial results.  Stroke. 2003 May;34(5):e29-33.

 

  1. Bateman B, Meyers PM, Schumacher HC, Mangla S, Pile-Spellman J. Conducting stroke research with an exception from the requirement for informed consent. Stroke. 2003 May;34(5):1317-23.

 

  1. Joshi S, Hartl R, Sun LS, Libow AD, Wang M, Pile-Spellman J, Young WL, Connolly ES, Hirshman CA.  Despite in vitro increase in cyclic guanosine monophosphate concentrations, intracarotid nitroprusside fails to augment cerebral blood flow of healthy baboons. Anesthesiology. 2003 Feb;98(2):412-9.

 

  1. Feng L, Fitzsimmons BF, Young WL, Berman MF, Lin E, Aagaard BD, Duong H, Pile-Spellman J. Intraarterially administered verapamil as adjunct therapy for cerebral vasospasm: safety and 2-year experience. AJNR Am J Neuroradiol. 2002 Sep;23(8):1284-90.

 

  1. Stapf C, Mohr JP, Pile-Spellman J, Sciacca RR, Hartmann A, Schumacher HC, Mast H. Concurrent arterial aneurysms in brain arteriovenous malformations with haemorrhagic presentation. J Neurol Neurosurg Psychiatry. 2002 Sep;73(3):294-8.

 

  1. Bustillo MA, Lazar RM, Finck AD, Fitzsimmons B, Berman MF, Pile-Spellman J, Heyer EJ. Dexmedetomidine may impair cognitive testing during endovascular embolization of cerebral arteriovenous malformations: a retrospective case report series. J Neurosurg Anesthesiol. 2002 Jul;14(3):209-12.

 

  1. Hartmann A, Pile-Spellman J, Stapf C, Sciacca RR, Faulstich A, Mohr JP, Schumacher HC, Mast H. Risk of endovascular treatment of brain arteriovenous malformations. Stroke. 2002 Jul;33(7):1816-20.

 

  1. Marshall RS, Lazar RM, Young WL, Solomon RA, Joshi S, Duong DH, Rundek T, Pile-Spellman J. Clinical utility of quantitative cerebral blood flow measurements during internal carotid artery test occlusions. Neurosurgery. 2002 May;50(5):996-1005.

 

  1. Stapf C, Connolly ES, Schumacher HC, Sciacca RR, Mast H, Pile-Spellman J, Mohr JP.  Dysplastic vessels after surgery for brain arteriovenous malformations. Stroke. 2002 Apr;33(4):1053-6.

 

  1. Gupta DK, Young WL, Hashimoto T, Halim AX, Marshall RS, Lazar RM, Joshi S, Pile-Spellman J, Ostapkovich N. Characterization of the cerebral blood flow response to balloon deflation after temporary internal carotid artery test occlusion. J Neurosurg Anesthesiol. 2002 Apr;14(2):123-9.

 

  1. Joshi S, Duong H, Mangla S, Wang M, Libow AD, Popilskis SJ, Ostapkovich ND, Wang TS, Young WL, Pile-Spellman J. In non-human intracarotid adenosine, but not sodium nitroprusside, increases cerebral blood flow. Anesth Analg. 2002 Feb;94(2):393-9.

 

  1. Joshi S, Young WL, Duong H, Aagaard BA, Ostapkovich ND, Connolly ES, Pile-Spellman J. Intracarotid nitroprusside does not augment cerebral blood flow in human subjects. Anesthesiology. 2002 Jan;96(1):60-6.

 

  1. Hashimoto T, Mesa-Tejada R, Quick CM, Bollen AW, Joshi S, Pile-Spellman J, Lawton MT, Young WL. Evidence of increased endothelial cell turnover in brain arteriovenous malformations. Neurosurgery. 2001 Jul;49(1):124-32.

 

  1. Bernardini GL, Mayer SA, Kossoff SB, Hacein-Bey L, Solomon RA, Pile-Spellman J. Anticoagulation and induced hypertension after endovascular treatment for ruptured intracranial aneurysms. Crit Care Med. 2001 Mar;29(3):641-4.

 

  1. Marshall RS, Lazar RM, Pile-Spellman J, Young WL, Duong DH, Joshi S, Ostapkovich N. Recovery of brain function during induced cerebral hypoperfusion. Brain. 2001 Jun;124(Pt 6):1208-17.

 

  1. Joshi S, Hashimoto T, Ostapkovich N, Pile-Spellman J, Duong DH, Hacien-Bey L, Marshall RS, James DJ, Young WL. Effect of intracarotid papaverine on human cerebral blood flow and vascular resistance during acute hemispheric arterial hypotension. J Neurosurg Anesthesiol. 2001 Apr;13(2):146-51.

 

  1. Lazar RM, Marshall RS, Prell GD, Pile-Spellman J. The experience of Wernicke’s aphasia. Neurology. 2000 Oct 24;55(8):1222-4.

 

  1. Stapf C, Mohr JP, Sciacca RR, Hartmann A, Aagaard BD, Pile-Spellman J, Mast H. Incident hemorrhage risk of brain arteriovenous malformations located in the arterial borderzones. Stroke. 2000 Oct;31(10):2365-8.

 

  1. Hashimoto T, Young WL, Aagaard BD, Joshi S, Ostapkovich ND, Pile-Spellman J. Adenosine-induced ventricular asystole to induce transient profound systemic hypotension in patients undergoing endovascular therapy. Dose-response characteristics. Anesthesiology. 2000 Oct;93(4):998-1001.

 

  1. Joshi S, Young WL, Duong DH, Ostapkovich ND, Aagaard BD, Hashimoto T, Pile-Spellman J. Intracarotid infusion of the nitric oxide synthase inhibitor, L-NMMA, modestly decreases cerebral blood flow in human subjects. Anesthesiology. 2000 Sep;93(3):699-707.

 

  1. Massoud TF, Hademenos GJ, Young WL, Gao E, Pile-Spellman J. Can induction of systemic hypotension help prevent nidus rupture complicating arteriovenous malformation embolization?: analysis of underlying mechanism achieved using a theoretical model. AJNR Am J Neuroradiol. 2000 Aug;21(7):1255-67.

 

  1. Berman MF, Sciacca RR, Pile-Spellman J, Stapf C, Connolly ES Jr, Mohr JP, Young WL. The epidemiology of brain arteriovenous malformations. Neurosurgery. 2000 Aug;47(2):389-96; discussion 397. Review. 

 

  1. Lazar RM, Marshall RS, Pile-Spellman J, Duong HC, Mohr JP, Young WL, Solomon RL, Perera GM, DeLaPaz RL. Interhemispheric transfer of language in patients with left frontal cerebral arteriovenous malformation. Neuropsychologia. 2000;38(10):1325-32.

 

  1. Solomon RA, Connolly ES Jr, Prestigiacomo CJ, Khandji AG, Pile-Spellman J. Management of residual dysplastic vessels after cerebral arteriovenous malformation resection: implications for postoperative angiography. Neurosurgery. 2000 May;46(5):1052-62.