Zirka Anastasian, MD
Assistant Professor of Clinical Anesthesiology
Dr. Anastasian’s research interests focus on perioperative and intraoperative predictors of postoperative patient outcome including intraoperative blood pressure management, fluid management, and anesthetic management. She is currently collaborating on prospective clinical studies related to neurocognitive outcome as well as evaluating the effects of predictors of outcome using multi-center databases.
Dr. Joshi's main research interest is the delivery of drugs by the intraarterial route to treat brain diseases. To do so the laboratory uses cutting edge optical methods to track drugs and tracers and monitor their physiological effects in whole animal models. Funded by the National Cancer Institute, the laboratory is the center of a multi-institutional research program optical engineers and pharmaceutical researchers in several universities. By using optical sensing and imaging methods such as, diffuse reflectance spectroscopy, ultraviolet spectroscopy, multispectral imaging, hyper-spectral imaging, optical coherence tomography, and infrared thermal imaging, the laboratory is developing novel drug delivery methods and drug formulations for the intraarterial treatment of brain cancer, stroke and cerebral vasospasm.