Charles W. Emala, MD
Professor of Anesthesiology
Dr. Emala's main area of research interest is in the understanding of interactions between signal transduction pathways in airway nerves and smooth muscle and how these interactions contribute to diseases such as asthma. Interaction of anesthetic agents with muscarinic and GABA receptors on airway nerves and smooth muscle is a particular focus of these studies. A broader understanding of the non-neuronal expression and function of GABAA receptors in smooth muscle is a central focus. The laboratory uses whole animal airway physiology studies, isolated contractile studies of airway and vascular smooth muscle and biochemical and molecular biological techniques in elucidating the expression and function of signaling molecules.
George Gallos, MD
Assistant Professor of Anesthesiology
My research interests includes mechanisms of smooth muscle relaxation, in particular the role GABAA channels may play in modulating airway smooth muscle and uterine smooth muscle relaxation.