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Jonathan Hupf completed a B.A. from New York University in 2008. He began as a research assistant in April 2011 at Columbia University Medical Center, subsequent his post-undergraduate tenure in the legal field.
He primarily works on the ALS and PLS "COSMOS" studies (formally titled "Multicenter ALS Cohort Study of Oxidative Stress and Disease Progression" and "Multicenter PLS Cohort Study of Oxidative Stress and Disease Progression"). Both studies are trying to determine whether a physiological process known as "oxidative stress" has any impact on the rate of disease progression in sporadic ALS and PLS. Oxidative stress is often triggered by certain environmental exposures, diet, smoking, alcohol consumption, physical activity and psychological stress.
He is also currently working on a pilot study attempting to evaluate the test-retest reliability of conducting a modified cognitive testing battery in clinic face-to-face versus over the telephone. The findings will determine if over-the-phone cognitive testing will be performed in a larger project slated to begin in summer 2014.