Peter W. Grabham, Ph.D.

 Center for Radiological Research

Contact Information: 

Center for Radiological Research
630 West 168th Street, VC 11-243
New York, N.Y. 10032

Tel: 212-305-0845
Fax: 212-305-3229 

Email: pwg2@cumc.columbia.edu

Education

Undergraduate:

Bsc (hons), Wolverhampton University, UK

Graduate:

Ph.D, University of Birmingham, UK

Research

Effects of ionizing radiation on the structure and function of 3-dimensional vessel models.

Bystander response in vessel tissue models.

Effects of ionizing radiation on cell motility and the cytoskeleton.

Publications

 Grabham PW, Seale GE, Bennecib M, Goldberg DJ and Vallee RB. Cytoplasmic dynein and LIS1 are required for microtubule advance during growth cone remodeling and fast axonal outgrowth. J Neurosci 27:5823-34, 2007. 

Grabham PW, Wu F, Schacher S and Goldberg DJ. Initiating morphological changes associated with long-term facilitation in Aplysia is independent of transcription or translation in the cell body. J Neurobiol 64:202-12, 2005.

Rybin VO, Grabham PW, Elouardighi H and Steinberg SF. Caveolae-associated proteins in cardiomyocytes: caveolin-2 expression and interactions with caveolin-3. Am J Physiol Heart Circ Physiol 285:H325-32, 2003.

Grabham PW, Foley M, Umeojiako A and Goldberg DJ. Nerve growth factor stimulates coupling of beta1 integrin to distinct transport mechanisms in the filopodia of growth cones. J Cell Sci 113 ( Pt 17):3003-12, 2000. [Abstract]

Goldberg DJ, Foley MS, Tang D and Grabham PW. Recruitment of the Arp2/3 complex and mena for the stimulation of actin polymerization in growth cones by nerve growth factor. J Neurosci Res 60:458-67, 2000. 

Goldberg DJ and Grabham PW. Braking news: calcium in the growth cone. Neuron 22:423-5, 1999.

Grabham PW and Goldberg DJ. Nerve growth factor stimulates the accumulation of β1 integrin at the tips of filopodia in the growth cones of sympathetic neurons. J Neurosci 17:5455-65, 1997.

Grabham PW, Wu D-Y and Goldberg DJ. Protein tyrosine phosphorylation in the growth cone. In: Nerve Growth and Guidance, ed. C. McCaig, Portland Press, pp. 7-19, 1996.

Grand RJ, Turnell AS and Grabham PW. Cellular consequences of thrombin-receptor activation. Biochem J 313 ( Pt 2):353-68, 1996.

Grabham P and Cunningham DD. Thrombin receptor activation stimulates astrocyte proliferation and reversal of stellation by distinct pathways: involvement of tyrosine phosphorylation. J Neurochem 64:583-91, 1995.