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Megan Sykes, MD

  • Sachs DH, Kawai T, Sykes M. Induction of Tolerance Through Mixed Chimerism. In: Turka L, Wood K, editors. Cold Spring Harbor Perspectives; 2013. 2014 Jan 1;4(1):a015529. doi: 10.1101/cshperspect.a015529.
  • Haspot F, Li HW, Lucas CL, Fehr T, Beyaz S, Sykes M. Allospecific rejection of MHC class I-deficient bone marrow by CD8 T cells. American Journal of Transplantation, 2014 Jan 14(1): 49-58. doi: 10.1111/ajt.12525. PMID: 24304495. PMCID: PMC4045013.
  • Griesemer A, Yamada K, Sykes M. Xenotransplantation: Immunological hurdles and progress toward tolerance. Immunological Reviews; 2014 Mar;258(1):241-58. doi: 10.1111/imr.12152. PMID: 24517437. PMCID: PMC4023346.
  • Sykes M. Transplantation: Moving to the Next Level. Immunological Reviews; 2014. 2014 Mar;258(1):5-11. doi: 10.1111/imr.12161. PMID: 24517422. PMCID: PMC4038030.
  • Sykes M. Transplantation Immunology. In: The Cecil Text Book of Medicine, 25th Edition. (Eds), Goldman L, Ausiello, D. Philadelphia, PA; Saunders Elsevier; 2014; (In Press)
  • Kalscheuer H, Onoe T, Dahmani A, Holzl M, Yamada K, Sykes M. Xenograft tolerance and immune function of human T cells developing in pig thymus xenografts. Journal of Immunology, 2014 Apr 1;192(7):3442-50. doi: 10.4049/jimmunol.1302886. PMID: 24591363. PMCID: PMC3983999.
  • Li H, Yang YG, Sykes M. Thymic education of human T cells and regulatory T cell development in humanized mice. In: Humanized Mice for HIV Research; Poluektova LY, Garcia-Martinez JV, Koyanagi Y, Manz MG, Tager AM (Ed.), New York, NY, Springer Science+Business Media; 2014; 10: (page number to be determined) (In Press)
  • Kawai T, Sachs DH, Sprangers B, Spitzer T, Saidman S, Zorn E, Tolkoff-Rubin N, Preffer F, Crisalli K, Gao B, Wong W, Morris H, LoCascio S, Sayre P, Shonts B, Williams W, Smith R, Colvin R, Sykes M, Cosimi A. Long-Term Results in Recipients of Combined HLA-Mismatched Kidney and Bone Marrow Transplantation Without Maintenance Immunosuppression. American Journal of Transplantation. 2014 June 5; XX:1-13. doi: 10.1111/ajt.12731. PMID: 24903438.
  • H. Morris, S. DeWolf, H. Robins, B. Sprangers, S. A. LoCascio, B. A. Shonts, T. Kawai, W. Wong, S. Yang, J. Zuber, Y. Shen, M. Sykes, Tracking donor-reactive T cells: Evidence for clonal deletion in tolerant kidney transplant patients. Sci. Transl. Med. 7, 272ra10 (2015).
  • Zuber J, Rosen S, Shonts B, Sprangers B, Savage T, Richman S, Yang S, Lau S, DeWolf S, Vlad G, Zorn E, Wong W, Emond J, Martinez M, Kato T, Sykes, M. Macrochimerism in intestinal transplantation: association with lower rejection rates and multivisceral transplants, without GVHD. American Journal of Transplantation. 2015 Oct 15(10):2691-703 doi: 10.1111/ajt. 13325. Epub 2015 May 18. PMC4575629.
  • DeWolf, S., Y. Shen, and M. Sykes, A New Window into the Human Alloresponse. Transplantation, 2016. PubMed PMID: 26760572
  • DeWolf S, Morris H, Shen Y, Sykes M.  Author response to comment on Tracking donor-reactive T cells: Evidence for clonal deletion in tolerant kidney transplant patients. Science Translational Medicine.  2015 Jul 22; 7(297):297Ir1. Doi: 10.1126/scietranslmed.aac9461.
  • Julien Zuber, Brittany Shonts, Sai-Ping Lau, Aleksandar Obradovic, Jianing Fu, Suxiao Yang,Marion Lambert, Shana Coley, Joshua Weiner, Joseph Thome, Susan DeWolf, Donna L. Farber, Yufeng Shen, Sophie Caillat-Zucman,Govind Bhagat. Adam Griesemer, Mercedes Martinez, Tomoaki Kato,and Megan Sykes. Bidirectional intragraft alloreactivity drives the repopulation of human intestinal allografts and correlates with clinical outcome. Science Immunology, 07 Oct, 2016: Vol. 1., Issue 4, DOI:10.1126/sciimmunol.aah3732. Read full text here.
  • Gao B, Gu Y, Rong C, Moore C, Porcheray F, Wong W, Preffer FI, Saidman SL, Fu Y, AB Cosimi B, Sachs DH, Kawai T, Sykes M, Zorn E.  Dynamics of B cell recovery following kidney/bone marrow transplant recipients.  Transplantation. 2017 Apr 19. doi: 10.1097/ TP.0000000000001789. [Epub ahead of print] PMID: 28422925
  • DeWolf S, Sykes M. Alloimmune T cells in transplantation. J Clin Invest. 2017 Jun 30;127(7):2473-2481. doi: 10.1172/JCI90595. Epub 2017 Jun 19. PMCID: PMC5490749
  • Zuber J, Sykes M. Mechanisms of Mixed Chimerism-Based Transplant Tolerance. Trends Immunol. 2017 Aug 18. pii: S1471-4906(17)30146-1. doi: 10.1016/ [Epub ahead of print] PMID: 28826941
  • Yamada K, Sykes M, Sachs D. Tolerance in xenotransplantation. Curr Opin Organ Tran. 2017. In Press
  • Sprangers B, DeWolf S, Savage T, Morokata T, Obradovic A, LoCascio S, Shonts B, Zuber J, Lau SP, Shah R, Morris H, Steshenko V, Zorn E, Preffer F, Olek S, Dombkowski D, Turka L, Colvin R, Winchester R, Kawai T, Sykes M. Origin of enriched regulatory T cells in patients receiving combined kidney/bone marrow transplantation to induce transplantation tolerance. American Journal of Transplantation (2017). DOI: 10.1111/ajt.14251- PMID:2825180

David Sachs, MD

  • Tasaki M, Villani V, Shimizu A, Sekijima M, Yamada R, Hanekamp IM, Hanekamp JS, Cormack TA, Moran SG, Kawai A, Sachs DH, Yamada K.  Role of Bone Marrow Maturity, Insulin-like Growth Factor 1 Receptor and Forkhead Box Protein N1 in Thymic Involution and Rejuvenation.  Am J Transplant. 2016 May 4. In press.
  • Tena A, Sachs DH, Mallard C, Yang Y, Tasaki M, Farkash E, Rosales I, Colvin RB, Leonard DA, Hawley RJ. Prolonged Survival of Pig Skin on Baboons following Administration of Pig Cells Expressing Human CD47. Transplantation. In press.
  • Shah JA, Navarro-Alvarez N, DeFazio M, Rosales IA, Elias N, Yeh H, Colvin RB, Cosimi AB, Markmann JF, Hertl M, Sachs DH, Vagefi PA.  A Bridge to Somewhere: 25-day Survival after Pig-to-Baboon Liver Xenotransplantation. Ann Surg. 2016 Jan 28. [Epub ahead of print] No abstract available. PMCID: PENDING.
  • Buhler L, Illigens BM, Nadazdin O, Tena A, Lee S, Sachs DH, Cooper DK, Benichou G. Persistence of indirect but not direct T cell xenoresponses in baboon recipients of pig cell and organ transplants. Am J Transplant. 2015 Dec 31. doi: 10.1111/ajt.13695. PMCID: PENDING.
  • Sihag S, Haas MS, Kim KM, Guerrero JL, Beaudoin J, Alicot EM, Schuerpf F, Gottschall JD, Puro RJ, Madsen JC, Sachs DH, Newman W, Carroll MC, Allan JS. Natural IgM Blockade Limits Infarct Expansion and Left Ventricular Dysfunction in a Swine Myocardial Infarct Model. Circ Cardiovasc Interv. 2016 Jan;9(1):e002547. PMCID: PMC4687758.
  • Wang Z, Pratts SG, Zhang H, Spencer PJ, Yu R, Tonsho M, Shah JA, Tanabe T, Powell HR, Huang CA, Madsen JC, Sachs DH, Wang Z. Treg depletion in non-human primates using a novel diphtheria toxin-based anti-human CCR4 immunotoxin. Mol Oncol. 2015 Nov 19. PMCID: PMC4826841.
  • Navarro-Alvarez N, Shah JA, Zhu A, Ligocka J, Yeh H, Elias N, Rosales I, Colvin R, Cosimi AB, Markmann JF, Hertl M, Sachs DH, Vagefi PA. The Effects of Exogenous Administration of Human Coagulation Factors Following Pig-to-Baboon Liver Xenotransplantation. Am J Transplant. 2015 Nov 27. doi: 10.1111/ajt.13647. [Epub ahead of print] PMCID: IN PROCESS.
  • Cetrulo CL Jr, Drijkoningen T, Sachs DH. Tolerance induction via mixed chimerism in vascularized composite allotransplantation: is it time for clinical application? Curr Opin Organ Transplant. 2015 Dec;20(6):602-7. doi: 10.1097/MOT.0000000000000248. PMCID: N/A.
  • Duran-Struuck R, Huang CA, Orf K, Bronson RT, Sachs DH, Spitzer TR. Miniature Swine as a Clinically Relevant Model of Graft-Versus-Host Disease. Comp Med. 2015 Oct;65(5):429-43. PMCID: PMC4617335.
  • Madariaga ML, Spencer PJ, Michel SG, La Muraglia GM 2nd, O'Neil MJ, Mannon EC, Leblang C, Rosales IA, Colvin RB, Sachs DH, Allan JS, Madsen JC. Effects of Lung Cotransplantation on Cardiac Allograft Tolerance Across a Full Major Histocompatibility Complex Barrier in Miniature Swine. Am J Transplant. 2015 Oct 15. doi: 10.1111/ajt.13489. [Epub ahead of print] PMCID: IN PROCESS.
  • Newell KA, Asare A, Sanz I, Wei C, Rosenberg A, Gao Z, Kanaparthi S, Asare S, Lim N, Stahly M, Howell M, Knechtle S, Kirk A, Marks WH, Kawai T, Spitzer T, Tolkoff-Rubin N, Sykes M, Sachs DH, Cosimi AB, Burlingham WJ, Phippard D, Turka LA. Longitudinal studies of a B cell-derived signature of tolerance in renal transplant recipients. Am J Transplant. 2015 Nov;15(11):2908-20. doi: 10.1111/ajt.13480. Epub 2015 Oct 13. PMCID: PMC4725587.
  • Navarro Alvarez N, Zhu A, Arellano RS, Randolph MA, Duggan M, Scott Arn J, Huang CA, Sachs DH, Vagefi PA. Postnatal xenogeneic B-cell tolerance in swine following in utero intraportal antigen exposure. Xenotransplantation. 2015 Sep;22(5):368-78. doi: 10.1111/xen.12186. Epub 2015 Aug 28. PMCID: IN PROCESS.
  • Pathiraja V, Villani V, Tasaki M, Matar AJ, Duran-Struuck R, Yamada R, Moran SG, Clayman ES, Hanekamp J, Shimizu A, Sachs DH, Huang CA, Yamada K. Tolerance of Vascularized Islet-Kidney Transplants in Rhesus Monkeys. Am J Transplant. 2017 Jan; 17(1):91-102. doi: 10.1111/ajt.13952. PMCID: PMC5195889.
  • Tena A, Sachs DH, Mallard C, Yang Y, Tasaki M, Farkash E, Rosales I, Colvin RB, Leonard DA, Hawley RJ. Prolonged Survival of Pig Skin on Baboons following Administration of Pig Cells Expressing Human CD47. Transplantation. 2017 Feb; 101(2):316-321. PMCID: PMC5124423.
  • Holzer PW, Leonard DA, Shanmugarajah K, Moulton KN, Ng ZY, Cetrulo CL Jr, Sachs DH. A Comparative Examination of the Clinical Outcome and Histological Appearance of Cryopreserved and Fresh Split-Thickness Skin Grafts. J Burn Care Res. 2017 Jan/Feb; 38(1):e55-e61. PMCID: PMC5179303
  • Eliaz I, Patil A, Navarro-Alvarez N, Wang Z, Eliaz A, Weil E, Wilk B, Sachs DH, Huang CA. Methods for the detection and serum depletion of porcine galectin-3. J Clin Apher. 2017 Jan 13. PMCID: N/A.

Markus Mapara, MD, PhD

  • Ganjoo KN, de Vos S, Pohlman BL, Flinn IW, Forero-Torres A, Enas NH, Cronier DM, Dang NH, Foon KA, Carpenter SP, Slapak CA, Link BK, Smith MR, Mapara MY, Wooldridge JE. Phase 1/2 Study of Ocaratuzumab, an Fc-Engineered Humanized Anti-CD20 Monoclonal Antibody, in Low-Affinity FcγRIIIa Patients with Previously Treated Follicular Lymphoma. Leuk Lymphoma. 2014 Jul 14:1-7. [Epub ahead of print] PMID: 24717109 [PubMed - as supplied by publisher] PMCID IN PROGRESS
  • Choi SW, Braun T, Chang L, Ferrara JL, Pawarode A, Magenau JM, Hou G, Beumer JH, Levine JE, Goldstein S, Couriel DR, Stockerl-Goldstein K, Krijanovski OI, Kitko C, Yanik GA, Lehmann MH, Tawara I, Sun Y, Paczesny S, Mapara MY, Dinarello CA, DiPersio JF, Reddy P. Lancet Vorinostat plus tacrolimus and mycophenolate to prevent graft-versus-host disease after related-donor reduced-intensity conditioning allogeneic haemopoietic stem-cell transplantation: a phase 1/2 trial. Oncol. 2014 Jan;15(1):87-95. doi: 10.1016/S1470-2045(13)70512-6. Epub 2013 Nov 30. PMID: 24295572 [PubMed - indexed for MEDLINE] PMCID: PMC4103793

Ran Reshef, MD

  • Pasquini MC, Zhang MJ, Medeiros BC, Armand P, Hu ZH, Nishihori T, Aljurf MD, Akpek G, Cahn JY, Cairo MS, Cerny J, Copelan EA, Deol A, Freyl CO, Gale RP, Ganguly S, George B, Gupta V, Hale GA, Kamble RT, Kulmpp TR, Lazarus HM, Luger SM, Liesveld JL, Litzow MR, Marks DI, Martino R, Norkin M, Olsson RF, Oran B, Pawarode A, Pulsipher MA, Ramanathan M, Reshef R, Saad AA, Saber W, Savani BN, Schouten HC, Ringden O, Tallman MS, Uy GL, Wood, WA, Wirk B, Perez WS, Batiwalla M, Weisdorf DJ (2016). Hematopoietic Cell Transplantation Outcomes in Monosomal Karyotype Myeloid Malignancies. Biol Blood Marrow Transplant 22:248-257
  •  Meng L, Bai Z, He S, Mochizuki K, Liu Y, Purushe J, Sun H, Wang J, Yagita H, Mineishi S, Fung H, Yanik GA, Carrichio R, Fan X, Crisalli LM, Hexner EO, Reshef R, Zhang Y, Zhang Y (2016). “The Notch ligand DLL4 defines a unique capability of human dendritic cells in regulating Th1 and Th17 differentiation” J Immunol 196:1070-1080
  • Ganetsky A, Shah A, Miano TA, Hwang WT, He J, Loren AW, Hexner EO, Frey NV, Porter DL, Reshef R (2016). “Higher Tacrolimus Concentrations Early After Transplant Reduce the Risk of Acute GvHD in Reduced-Intensity Allogeneic Stem Cell Transplantation” Bone Marrow Transplant 51:568-572
  • Seftel MD, Neuberg D, Zhang MJ, Wang HL, Ballen KK, Bergeron J, Couban S, Freytes CO, Hamadani M, Kharfan-Dabaja MA, Lazarus HM, Nishihori T, Paulson K, Saber W, Sallan SE, Soiffer R, Tallman MS, Woolfrey AE, DeAngelo DJ, Weisdorf DJ; Collaborators: Akpek G, Baron F, Bashey A, Cahn JY, Camitta BM, Copelan EA, de Lima M, Deol A, Gale RP, Gergis U, Hogan WJ, Kebriaei P, Litzow MR, Loren AW, Miller AM, Norkin M, Olsson RF, Reshef R, Savani BN, Schouten HC, Vij R, Wiernik PH, Wirk B, Wood WA (2016). “Pediatric-inspired Therapy compared to Allografting for Philadelphia Chromosome Negative Adult ALL in First Complete Remission” Am J Hematol 91:322-329
  • Hexner EO, Luger SM, Reshef R, Jeschke GR, Mangan JK, Frey NV, Frank DM, Richman LP, Vonderheide RH, Aqui NA, Rosenbach M, Zhang Y, Chew A, Loren AW, Stadtmauer EA, Levine BL, June CH, Emerson SG, Porter DL (2016) “Infusion of CD3/CD28 co-stimulated umbilical cord blood T cells at the time of single umbilical cord blood transplantation may enhance engraftment” Am J Hematol 91:453-460
  • Kumar AJ, Vassilev P, Loren AW, Luger SM, Reshef R, Gill S, Smith J, Goldstein SC, Hexner EO, Stadtmauer EA, Porter DL, Frey NV (2016) “Time to Unrelated Donor Leukocyte Infusion is Longer, but Incidence of GVHD and Overall Survival are Similar for Recipients of Unrelated DLI Compared to Matched Sibling DLI” Am J Hematol 91:426-429
  • Shaffer BC, Ahn KW, Hu ZH, Nishihori T, Malone A, Valcárcel D, Grunwald MR, Bacher U, Hamilton B, Kharfan-Dabaja MA, Saad A, Cutler C, Warlick E, Reshef R, Wirk B, Sabloff M, Fasan O, Gerds A, Marks DI, Olsson RF, Wood WA, Costa LJ, Miller AM, Cortes J, Daly A, Kindwall-Keller T, Kamble R, Rizzieri D, Cahn JY, Gale RP, William BM, Litzow M, Wiernik PH, Liesveld J, Savani BN, Vij R, Ustun C, Copelan E, Popat U, Kalaycio M, Maziarz R, Alyea E, Sobecks R, Pavletic S, Tallman M, Saber W (2016) “A Scoring System Prognostic of Outcomes in Patients Undergoing Allogeneic Hematopoietic Cell Transplantation for Myelodysplastic Syndrome” J Clin Oncol (In Press)
  • Mochizuki K, Meng L, Mochizuki I, Tong Q, He S, Liu Y, Purushe J, Fung H, Zaidi RM, Zhang Y, Reshef R, Blazar BR, Yagita H, Mineishi S, Zhang Y (2016). “Programming of Donor T Cells Using Allogeneic Delta-like ligand 4-positive Dendritic Cells to Reduce GVHD in Mice” Blood (In Press)
  • Deol A, Sengsayadeth S, Ahn KW, Wang HL, Aljurf M, Antin JH, Battiwalla M, Bornhauser M, Cahn JY, Camitta B, Chen YB, Cutler CS, Gale RP, Ganguly S, Hamadani M, Inamoto Y, Jagasia M, Kamble R, Koreth J, Lazarus HM, Liesveld J, Litzow MR, Marks DI, Nishihori T,  Olsson RF, Reshef R, Rowe JM, Saad AA, Sabloff M, Schouten HC, Shea TC, Soiffer RJ, Uy GL, Waller EK, Wiernik PH, Wirk B, Woolfrey AE, Bunjes D, Devine S, de Lima M, Sandmaier BM, Weisdorf D, Khoury HJ, Saber W (2016). “Does FLT3 Mutation Impact Survival after Hematopoietic Cell Transplant for AML? A CIBMTR Analysis” Cancer (In Press)
  • Yam C, Crisalli L, Luger SM, Loren AW, HExner EO, Frey NV, Mangan JK, Gao A, Stadtmauer EA, Porter DL, Reshef R (2016). “Unrelated Donors are Associated with Improved Relapse Free Survival Compared to Related Donors in Patients with Myelodysplastic Syndrome Undergoing Reduced Intensity Allogeneic Stem-Cell Transplantation” Am J Hematol (In Press)
  • Ryan H. Moy, Austin P. Huffman, Lee P. Richman, Lisa Crisalli, Ximi K. Wang, James A. Hoxie, Rosemarie Mick, Stephen G. Emerson, Yi Zhang, Robert H. Vonderheide, David L. Porter and Ran Reshef. Clinical and immunologic impact of CCR5 blockade in graft-versus-host disease prophylaxis. Blood 2017 129:906-916

Remi Creusot, PhD

  • Creusot RJ, Giannoukakis N, Trucco M, Clare-Salzler MJ, Fathman CG. It's time to bring dendritic cell therapy to type 1 diabetes. Diabetes. 2014 Jan;63(1):20-30. (PMID: 24357690; PMCID: PMC3968436)
  • Yip L, Fuhlbrigge R, Taylor C, Creusot RJ, Nishikawa-Matsumura T, Whiting CC, Schartner JM, Akter R, von Herrath M, Fathman CG. Inflammation and hyperglycemia mediate Deaf1 splicing in the pancreatic lymph nodes via distinct pathways during type 1 diabetes. Diabetes. 2015 Feb;64(2):604-17. (PMID: 25187368; PMC4303971)
  • Johannesson B, Sui L, Freytes DO, Creusot RJ, Egli D. Toward beta cell replacement for diabetes. EMBO J. 2015 Apr 1;34(7):841-55. (PMID: 25733347; PMCID: PMC4388595)
  • Creusot RJ, Battaglia M, Roncarolo MG, Fathman CG. Cell-Based Therapies and Other Non-Traditional Approaches for Type 1 Diabetes. Stem Cells. 2016 Apr;34(4):809-19. (PMID: 26840009; PMCID: PMC5021120)
  • Dastagir SR, Postigo-Fernandez J, Xu C, Stoeckle JH, Firdessa-Fite R, Creusot RJ. Efficient Presentation of Multiple Endogenous Epitopes to Both CD4+ and CD8+ Diabetogenic T Cells for Tolerance. Mol Ther Methods Clin Dev. 2016 Dec 24;4:27-38. (PMID: 28344989; PMCID: PMC5363322)

Hans Snoeck, MD, PhD

  • Huang SX, Islam MN, O’Neill J, Hu Z, Yang Y-Y, Chen Y-W, Green MD, Mumau M, Vunakc-Novakovic G, Bhattacharya J, Snoeck HW. (2014) Highly efficient generation of lung and airway epithelial cells from human pluripotent stem cells. Nat Biotechnol., 32:84-91. PMID: 24291815 [PubMed - in process] PMCID: PMC4101921
  • Kamezaki K, Snoeck HW. (2014) Differential requirement of wild-type Flt3 in leukemic stem cells which is not reflected in vitro assays for leukemic stem cells. Exp Hematol, 32:84-91.
  • Baker SJ, Ma’ayan A, Lieu YK, John P, Reddy MVR, Chen EY, Duan Q, Snoeck HW, Reddy EP. (2014) B-myb is Essential Regulator of Hematopoietic Stem Cell and Myeloid Progenitor Cell Development. Proc. Natl. Acad Sci USA, 111:3122-3127. PMID: 24516162 [PubMed - indexed for MEDLINE] PMCID: PMC3939923.
  • Huang SX, Green M, Toste A, Mumau M, Chen YW, Snoeck HW. Protocol of for the generation of lung and airway epithelial cells from human pluripotent stem cells. Nat Protocols, in press.

Xiaojuan Chen, MD, PhD

  • Woodland D, Wei Liu, Liang J, Sears M, Chen X. Short-term high fat feeding induces islet macrophage infiltration and b-cell replication independent of cellular oxidative stress. AJP-Endocrinology & Metabolism 2016 (in revision).

Adam Griesemer, MD

  • Griesemer A, Yamada K, Sykes M. Xenotransplantation: immunological hurdles and progress toward tolerance. Immunological Reviews. Immunol Rev. 2014 Mar;258(1):241-58. PMID: 24517437
  • Weiner J, Wu J, Martinez M, Lobritto S, Ovchinsky N, Rohde C, Griesemer A, Kato T. The use of bi-planar tissue expanders to augment abdominal domain in a pediatric intestinal transplant recipient. Pediatric Transplantation. 2014 Aug: 18(5): E174–E179, PMID: 25041331.
  • Halazun KJ, Patzer RE, Rana AA, Verna EC, Griesemer AD, Parsons RF, Samstein B, Guarrera JV, Kato T, Brown RS Jr, Emond JC. Standing the test of time: Outcomes of a decade of prioritizing patients with HCC, results of the UNOS natural geographic experiment. Hepatology. 2014 Jun 20. PMID: 24954365.
  • Wang H, Griesemer AD, Parsons RF, Graham JA, Emond JC, Samstein B. Delayed gastric emptying after living donor hepatectomy for liver transplantation. Case Rep Transplant. 2014;2014:582183. PMCID: PMC4291134.
  • Case Rep Transplant. 2014;2014:582183.

Yong-Guang Yang, MD, PhD

  • Wang H, Yang YG. The complex and central role of interferon-g in graft-versus-host disease and graft-versus-tumor activity. Immunol Rev. 2014 Mar;258(1):30-44. NIHMSID 579492.
  • Huang SXL, Islam MN, O’Neil J, Hu Z, Yang YG, Chen YW, Mumau M, Green MD, Vunjak-Novakovic G, Battachariya J, Snoeck HW. Efficient generation of lung and airway epithelial cells from human pluripotent stem cells. Nat Biotechnol. 2014;32(1):84-91. doi: 10.1038/nbt.2754.
  • Navarro-Alvarez N, Yang YG. Lack of CD47 on donor hepatocytes promotes innate immune cell activation and graft loss: a potential barrier to hepatocyte xenotransplantation. Cell Transplant 2014;23(3):345-54. PMID: 23394628; PMCID: PMC3751988
  • Rong Z, Wang M, Hu Z, Stradner M, Zhu S, Kong H, Yi H, Goldrath A, Yang YG, Xu Y, Fu X. An effective approach to prevent immune rejection of human ESC-derived allografts. Cell Stem Cell 2014;2:14(1):121-30. doi: 10.1016/j.stem.2013.11.014. PMCID: PMC4023958.
  • Hu L, Cheng H, Gao Y, Shi M, Liu Y, Hu Z, Xu J, Qiu L, Yuan W, Leung AY, Yang YG, Cheng T. The antioxidant N-acetyl-L-cysteine increases engraftment of human hematopoietic stem cells in immune-deficient mice. Blood. 2014 Oct 6. pii: blood-2014-03-559369.
  • Wang Y, Wang H, Bronson R, Fu Y, Yang YG. Rapid dendritic cell activation and resistance to allotolerance induction in anti-CD154-treated mice receiving CD47-deficient donor-specific transfusion. Cell Transplant 2014;23(3):355-63. PMID: 23295133; PMCID: PMC3732805
  • Wang Y, Wang H, Ren L, Weng Q, Bao Y, Tian H, Yang YG, Li X. Non-mitogenic form of acidic fibroblast growth factor protects against graft-versus-host disease without accelerating leukemia. Int Immunopharmacol. 2014 Sep 16. pii: S1567-5769(14)00347-6. doi: 10.1016/j.intimp.2014.09.006.
  • Li HW, Yang YG, Sykes M. Thymic Education of Human T Cells and Regulatory T Cell Development in Humanized Mice (Chapter 11). In: Humanized Mice for HIV Research; Springer Science New York 2014, pp.127.
  • Hu Z, Yang YG. Biology of Human Hematopoietic Stem Cell Xenotransplantation in Mice (Chapter 5). In: Humanized Mice for HIV Research; Springer Science New York; 2014, pp.53.
  • Zhao T, Zhang ZN, Westenskow PD, Todorova D, Hu Z, Lin T, Rong Z, Kim J, He J, Wang M, Clegg DO, Yang YG, Zhang K, Friedlander M, Xu Y. Humanized Mice Reveal Differential Immunogenicity of Cells Derived from Autologous Induced Pluripotent Stem Cells. Cell Stem Cell. 2015 Sep 3;17(3):353-9. doi: 10.1016/j.stem.2015.07.021. Epub 2015 Aug 20.
  • Hu Z, Jin F, Chen B, Guo J, He J, Liu Z, Liu B, Yang YG. Humanized mouse models with functional human lymphoid and hematopoietic systems through human hematopoietic stem cell and human fetal thymic tissue transplantation (Chapter 9). In Hematopoietic Differentiation of Human Pluripotent Stem Cells; Springer Science New York; 2015, pp120.
  • Jin F, He J, Jin C, Fan W, Shan Y, Zhang Z, Sun L, Hu Z, Yang YG. Antithymocyte globulin treatment at the time of transplantation impairs donor hematopoietic stem cell engraftment. Cell Mol Immunology 2015 October 26 doi:10.1038/cmi.2015.922015. [Epub ahead of print]. NIHMSID: NIHMS726521
  • Hu Z, Xia J, Fan W, Wargo J, Yang YG. Human melanoma immunotherapy using tumor antigen-specific T cells generated in humanized mice. Oncotarget 2016 Jan 27. doi: 10.18632/oncotarget.7044. [Epub ahead of print].
  • Zhang M, Wang H, Tan S, Navarro-Alvarez N, Zheng Y, Yang YG. Donor CD47 controls T cell alloresponses and is required for tolerance induction following hepatocyte allotransplantation. Scientific Reports 2016;6:26839. PMCID: PMC4882503
  • Tena A, Sachs DH, Mallard C, Yang YG, Tasaki M, Farkash E, Rosales IA, Colvin RB, Leonard DA, Hawley RH.  Prolonged survival of pig skin on baboons after administration of pig cells expressing human CD47. Transplantation 2016 May 26. Epub 2016 May 26.
  • Wu H, Zhen Y, Xu ZG, Ma Z, Li H, Yu J, Wang XY, Yi H, Yang YG. Arginase-1-dependent promotion of Th17 differentiation and disease progression by MDSCs in systemic lupus erythematosus. Sci Transl Med. 2016 Mar 23;8(331):331ra40. doi: 10.1126/scitranslmed.aae0482. NIHMSID: NIHMS790036; PubMed Central PMCID: PMC4895207.
  • Xia J, Hu Z, Yoshihara S, Li Y, Jin C-H, Tan S, Li W, Chen QF, Sykes M, Yang YG.  Modeling Human Leukemia Immunotherapy in Humanized mice. EBioMedicine 2016;10:11-12. Epub 23 June 2016; doi:10.1016/j.ebiom.2016.06.028
  • Gao L, Chen K, Gao Q, Sun J, Yang YG. CD47 deficiency in tumor stroma promotes tumor progression by enhancing angiogenesis. Oncotarget (In press) DOI: 10.18632/oncotarget.9899 [Epub ahead of print June 07 2016].
  • Gao Q, Chen K, Gao L, Zheng Y, Yang YG. Thrombospondin-1 signaling through CD47 inhibits cell cycle progression and induces senescence in endothelial cells. Cell Death & Disease 2016;7,e2368; doi:10.1038/cddis.2016.155; Published online 8 September 2016.

Donna Farber, PhD

  • Turner, D.L., Bickham, K.L., Thome, J.J.T., Kim, C., D’Ovidio, F., Wherry, E.J. and Farber, D.L. (2014) Lung resident niches for the generation and maintenance of influenza-specific memory T cells. Mucosal Immunology. 7:501-10.
  • Farber, D.L. , Yudanin, N.A. and Restifio, N.P. (2014) Human Memory T cells: generation, compartmentalization and homeostasis. Nature Reviews Immunology.14:24-35. (featured on cover)
  • Turner, D.L., Gordon, C.L. and Farber, D.L. (2014) Tissue resident T cells, in situ immunity and transplantation. Immunol. Reviews. 258:150-166.
  • Subramanian, M., Hayes, C.D., Thome, J.J., Thorp, E., Matsushima, G.K., Herz, J., Farber, D.L., Liu, K., Lakshmana, M. and Tabas, I. (2014) A Multiprotein Complex of Axl, LRP-1, and RanBP9 Mediates Dendritic Cell Efferocytosis and Antigen Cross-Presentation In Vivo. J. Clin. Invest. 124:1296-308.
  • Zens, K.D. and Farber, D.L. (2014) Memory CD4 T cell responses to influenza virus. Current Topics in Microbiology and Immunology. [Epub ahead of print].
  • Turner, D.L. and Farber, D.L. (2014) Mucosal resident memory CD4 T cells in protection and immunopathology. Front. Immunol. 5:331
  • Camirand, G., Wang, Y., Lu, Y. Wan, Y.Y., Lin, Y., Deng, S., Guz, G., Perkins, D.L., Finn, P.W., Farber, D.L., Flavell, R.A., Shlomchik, W.D., Lakkis, F.G., Rudd, C.E., and Rothstein, D.M. (2014) CD45 Ligation increases antigen-mediated expansion of regulatory T cell by promoting interactions with dendritic cells in vivo. J. Clin. Invest. In Press.
  • Thome, J.J.C., Yudanin, N.A., Ohmura, Y., Kubota, M., Grinshpun, B., Sathaliyawala, T., Kato, T., Lerner, H., Shen, Y. and Farber, D.L. (2014) Spatial map of human T cell compartmentalization and maintenance over decades of life. Cell. In Press.
  • Brestoff,J.R., Kim,B.S., Saenz,S.A., Stine,R.R., Monticelli,L.A., Sonnenberg,G.A., Thome,J.J.T., Farber,D.L., Lutfy,K., Seale, P., and Artis, D. (2014) Group 2 innate lymphoid cells promote beiging of white adipose tissue and limit diet-induced obesity. Nature, doi: 10.1038/nature14115.
  • Connors TJ, Ravindranath TM, Bickham KL, Gordon CL, Zhang F, Levin B, Baird JS, Farber DL. Airway CD8(+) T Cells Are Associated with Lung Injury during Infant Viral Respiratory Tract Infection. American Journal of Respiratory and Critical Care Medicine.PMC4942220. 10.1165/rcmb.2015-02970
  • Zens KD and Farber DL. Memory CD4 T cells in Influenza. In Compans RW and Oldstone MBA (Eds.) Current Topics in Microbiology and Immunology Cham, CH: Springer International. PMID:25005927. PMCID: PMC4339101.
  • Zens KD, Chen JK, Farber DL. Vaccine-Generated Lung Tissue-Resident Memory T cells Provide Heterosubtypic Protection to Influenza Infection. JCI Insights JCI Insight. 2016;1(10):e85832.doi:10.1172/jci.insight.85832.
  • Donna Farber, Thome J, Grinshpun B, Kumar B, Kubota M, Ohmura Y, Lerner H, Sempowski G, Shen Y. Long term maintenance of human naïve T cells through in situ homeostasis in lymphoid tissue sites. Science Immunology. 02 Dec 2016: Vol. 1, Issue 6, DOI: 10.1126/sciimmunol.aah6506
  • Tomer Granot, Takashi Senda, Dustin J. Carpenter, Nobuhide Matsuoka, Joshua Weiner, Claire L. Gordon, Michelle Miron, Brahma Kumar, Adam Griesemer, Siu-Hong Ho, Harvey Lerner, Joseph J.C. Thome, Thomas Connors, Boris Reizis, and Donna L. Farber. Dendritic cells display subset and tissue-specific maturation dynamics over human life.  Immunity.
  • Kumar, B.V., Ma, W. Miron, M., Granot, T., Guyer, R.S., Carpenter, D.J., Senda, T., Ho, S.-H., Lerner, H., Friedman, A.L., Shen, Y., Farber, D.L. (2017) Human tissue-resident memory T cells are defined by core transcriptional and functional signatures in lymphoid and mucosal sites. Cell Reports. In Press.
  • Zens, K.D., Chen, J.-K., Guyer, R.S., Wu, F.L., Cvetkovski, F., Miron, M. and Farber, D.L. (2017) Reduced generation of lung-tissue resident memory T cells during infancy. J. Exp. Med. In Press.

Emmanuel Zorn, PhD

  • Gao B, Moore C, Porcheray F, Rong C, Abidoglu C, DeVito J, Paine R, Girouard TC, Saidman SL, Schoenfeld D, Levin B, Wong W, Elias N, Schuetz C, Rosales I, Fu Y, Zorn E. Pretransplant IgG reactivity to apoptotic cells correlates with late kidney allograft loss. Am J Transplant. 2014 Jul;14(7):1581-91. doi: 10.1111/ajt.12763. Epub 2014 Jun 16. PMID: 24935695
  • Kawai T, Sachs DH, Sprangers B, Spitzer TR, Saidman SL, Zorn E, Tolkoff-Rubin N, Preffer F, Crisalli K, Gao B, Wong W, Morris H, LoCascio SA, Sayre P, Shonts B, Williams WW Jr, Smith RN, Colvin RB, Sykes M, Cosimi AB. Long-term results in recipients of combined HLA-mismatched kidney and bone marrow transplantation without maintenance immunosuppression. Am J Transplant. 2014 Jul;14(7):1599-611. doi: 10.1111/ajt.12731. Epub 2014 Jun 5. PMID: 24903438
  • Ferdman J, Porcheray F, Gao B, Moore C, DeVito J, Dougherty S, Thomas MV, Farkash EA, Elias N, Kawai T, Malek SK, Tullius SG, Wong W, Zorn E. Expansion and Somatic Hypermutation of B-cell Clones in Rejected Human Kidney Grafts. Transplantation. 2014 May 12. [Epub ahead of print] PMID: 24825521
  • Mengel M, Chong A, Rothstein DM, Zorn E, Maltzman JS. AST Cutting Edge of Transplantation 2013 Meeting Report: a comprehensive look at B cells and antibodies in transplantation. Am J Transplant. 2014 Mar;14(3):524-30. doi: 10.1111/ajt.12593. Epub 2014 Jan 24. PMID: 24674597
  • Yamada Y, Nadazdin O, Boskovic S, Lee S, Zorn E, Smith RN, Colvin RB, Madsen JC, Cosimi AB, Kawai T, Benichou G. Repeated Injections of IL-2 Break Renal Allograft Tolerance Induced via Mixed Hematopoietic Chimerism in Monkeys. Am J Transplant. 2015 Dec;15(12):3055-66. doi: 10.1111/ajt.13382. Epub 2015 Jul
  • Zuber J, Rosen S, Shonts B, Sprangers B, Savage TM, Richman S, Yang S, Lau SP, DeWolf S, Farber D, Vlad G, Zorn E, Wong W, Emond J, Levin B, Martinez M, Kato T, Sykes M. Macrochimerism in Intestinal Transplantation: Association With Lower Rejection Rates and Multivisceral Transplants, Without GVHD. Am J Transplant. 2015 Oct;15(10):2691-703.
  • Clerkin KJ, Farr MA, Restaino SW, Zorn E, Latif F, Vasilescu ER, Marboe CC, Colombo PC, Mancini DM. Donor-specific anti-HLA antibodies with antibody-mediated rejection and long-term outcomes following heart transplantation. J Heart Lung Transplant. 2016 Nov 17. pii: S1053-2498(16)30403-X. doi: 10.1016/j.healun.2016.10.016. [Epub ahead of print] PMID:27916323
  • Clerkin KJ, Restaino SW, Zorn E, Vasilescu ER, Marboe CC, Mancini DM. The effect of timing and graft dysfunction on survival and cardiac allograft vasculopathy in antibody-mediated rejection. J Heart Lung Transplant. 2016 Sep;35(9):1059-66. doi: 10.1016/j.healun.2016.04.007. PMID:27423693
  • Gao, B, Rong, C, Porcheray, F , Moore, C, Girouard, TC, Saidman, SL, Wong, W, Fu, Y, and Zorn, E. Evidence to support a contribution of polyreactive antibodies to HLA serum reactivity. Transplantation. 2016; PMID: 26285015 DOI:10.1097/TP.0000000000000840
  • Zorn E, See SB. Polyreactive natural antibodies in transplantation. Current Op Organ Transplant. 2017 Feb;22(1):8-13. doi: 10.1097/MOT.0000000000000376. PMID: 28005572

Joji Fujisaki, M.D., PhD

  • Yuichi Hirata, Hao-Wei Li, Kazuko Takahashi, Hiroshi Ishii, Megan Sykes and Joji Fujisaki; MHC class I expression by donor hematopoietic stem cells is required to prevent NK cell attack in allogeneic, but not syngeneic recipient mice, PLoS One, Nov 6, 2015. PMID: 26544200, PMCID:PMC4636372

Kazuhiko Yamada, M.D., PhD

  • Tasaki M, Shimizu A, Hanekamp I, Torabi R, Villani V, Yamada K.  The protective effects of Rituximab against early development of proteinuria in pig-to-baboon xeno kidney transplantation.  J Am Soc Nephrol. 2014 Apr;25(4):737-44.  PMID: 24459229
  • Kalscheuer H, Onoe T, Dahmani A, Li HW, Hölzl M, Yamada K, Sykes M.  Xenograft tolerance and immune function of human T cells developing in pig thymus xenografts. J Immunol. 2014 Apr 1;192(7):3442-50. PMID: 24591363
  • Lee PW, Hanekamp JS, Villani V, Vagefi PA, Cina RA, Kamano C, O'Malley PE, Arn S, Yamada K, Sachs DH.  Evidence for a Gene Controlling the Induction of Transplantation Tolerance.  Am J Transplant. 2014 Apr;14(4):952-9. PMID: 24592880
  • Yamada K, Tasaki T, Sekijima M, Wilkinson RA, Villani V, Moran SG, Cormack TA, Hanekamp IM, Arn S, Fishman JA, Shimizu A, Sachs DH.  Porcine CMV Infection Is Associated with Early Rejection of Kidney Grafts in a Pig to Baboon Xenotransplantation Model.  Transplantation 2014 Aug 27;98(4):411-8.
  • Griesemer A, Yamada K, Sykes M.  Xenotransplantation: immunological hurdles and progress toward tolerance.  Immunol Rev. 2014 Mar;258(1):241-58. PMID:24517437
  • Sekijima M, Waki S, Sahara H, Tasaki M, Wilkinson RA, Villani V, Shimatsu Y, Nakano K, Matsunari H, Nagashima H, Fishman JA Shimizu A and Yamada K.  Results of Life-Supporting GalT-KO kidneys in Cynomolgus Monkeys Using Two Different Sources of GalT-KO Swine Transplantation 2014 Aug 27. 98(4):419-26.
  • Scalea J, Okumi M, Villani V, Shimizu A, Nishimura H, Gillon BC, Torabi R, Cormack T, Moran S, LeGuern C, Sachs DH and Yamada K.  Abrogation of Renal Allograft Tolerance in MGH Miniature Swine: The Role of Intragraft and Peripheral Factors in Long-term Tolerance.  Am J Transplant 2014 Sep;14(9):2001-10. PMID: 25100613
  • Miura K, Sahara H, Sekijima M, Kawai A, Waki S, Nishimura S, Oku M, Clayman ES, Shimizu A and Yamada K. Protective Effect of Neutralization of the Extracellular High-Mobility Group Box-1 on Renal Ischemia-Reperfusion Injury in Miniature Swine.  Transplantation 2014 Nov 15;98(9):937-43. PMID: 25136847.
  • Scalea JR, Villani V, Gillon BC, Weiner J, Gianello P, Turcotte N, Arn JS, Yamada K, Sachs DH. Development of Antidonor Antibody Directed Toward Non-Major Histocompatibility Complex Antigens in Tolerant Animals. Transplantation. 2014 Sep 15;98(5):514-9 PMID:24933456.
  • Scalea JR, Torabi R, Tena A, Tasaki M, Gillon BC, Moran S, Cormack T, Villani V, Shimizu A, Sachs DH, Yamada K. The rejuvenating effects of leuprolide acetate on the aged baboon's thymus. Transpl Immunol. 2014 Sep 18;31(3):134-9. PMID: 25240733
  • Tasaki M, Wamala I, Tena A, Villani V, Sekijima M, Pathiraja V, Wilkinson R, Pratts S, Cormack T, Clayman E, Scott JA, Shimizu A, Fishman JA, Sachs DH, Yamada  K. High incidence of xenogenic bone marrow engraftment in pig-to-baboon intra-bone bone marrow transplantation.  Am J Transplant 2015 Apr;15(4):974-83.PMID: 25676635
  • Le Bas-Bernardet S, Tillou X, Branchereau J, Dilek N, Poirier N, Châtelais M, Charreau B, Minault D, Hervouet J, Renaudin K, Crossan C, Scobie L, Takeuchi Y, Diswall M, Breimer ME, Klar N, Daha MR, Simioni P, Robson SC, Nottle MB, Salvaris EJ, Cowan PJ, d'Apice AJ, Sachs DH, Yamada K, Lagutina I, Duchi R, Perota A, Lazzari G, Galli C, Cozzi E, Soulillou JP, Vanhove B, Blancho G.  Bortezomib, C1-Inhibitor and Plasma Exchange Do Not Prolong the Survival of Multi-Transgenic GalT-KO Pig Kidney Xenografts in Baboons.  Am J Transplant. 2015 Feb;15(2):358-70. doi: 10.1111/ajt.12988.
  • Wang P, Schuetz C, Vallabhajosyula P, Medarova Z, Tena A, Wei L, Yamada K, Deng S, Markmann JF, Sachs DH, Moore A.  Monitoring of allogeneic islet grafts in nonhuman primates using magnetic resonance imaging.  Transplantation. 2015, Aug;99(8):1574-81. PMID: 258064075
  • Madariaga MLL, Shanmugarajah K, Michel S, Villani V, Torabi R, Leonard D, Randolph M, Colvin R, Yamada K, Madsen JC, Cetrulo C, Sachs D. Immunomodulatory Strategies Directed Towards Tolerance of Vascularized Composite Allografts.  Transplantation 2015, Aug;99(8):1590-7. PMID: 25757218
  • Madariaga ML, Michel SG, La Muraglia GM 2nd, Sekijima M, Villani V, Leonard DA, Powell HJ, Kurtz JM, Farkash EA, Colvin RB, Allan JS, Cetrulo CL Jr, Huang CA, Sachs DH, Yamada K, Madsen JC.  Kidney-induced cardiac allograft tolerance in miniature swine is dependent on MHC-matching of donor cardiac and renal parenchyma.  Am J Transplant. 2015 Jun;15(6):1580-90. PMID: 25824550
  • Villani V, Yamada K, Scalea JR, Gillon BC, Arn JS, Sekijima M, Tasaki M, Cormack TA, Moran SG, Torabi R, Shimizu A, Sachs DH.  Adoptive Transfer of Renal Allograft Tolerance in a Large Animal Model.  Am J Transplant. Am J Transplant. 2016 Jan;16(1):317-24. [Epub ahead of print], PMID: 26260215
  • Book Chapter:  Yamada K*, Scalea J. Masayuki Tasaki.  Oxford Textbook of Transplant Anaesthesia (ed.  E Pretto).  Chapter 11: Xenotransplantation.  pp 111-123Oxford University Press. 2015
  • Miura K, Sahara H, Waki S, Kawai A, Sekijima M, Kobayashi T, Zhang Z, Wakai T, Shimizu A, Yamada K.  Development of the Intestinal Transplantation Model With Major Histocompatibility Complex Inbred CLAWN Miniature Swine. Transplant Proc. 2016 May;48(4):1315-9. PMID: 27320612
  • Tasaki M, Villani V, Shimizu A, Sekijima M, Yamada R, Hanekamp IM, Hanekamp JS, Cormack TA, Moran SG, Kawai A, Sachs DH, Yamada K. Role of Bone Marrow Maturity, Insulin-Like Growth Factor 1 Receptor, and Forkhead Box Protein N1 in Thymic Involution and Rejuvenation. Am J Transplant. 2016 Oct;16(10):2877-2891. Epub 2016 Jun 13. PMID: 27145342
  • Pathiraja V, Villani V, Tasaki M, Matar AJ, Duran-Struuck R, Yamada R, Moran SG, Clayman ES, Hanekamp J, Shimizu A, Sachs DH, Huang CA, Yamada K. Tolerance of Vascularized Islet-Kidney Transplants in Rhesus Monkeys. Am J Transplant. 2017 Jan;17(1):91-102. Epub 2016 Aug 9. PMID: 27376692
  • Tanabe T, Watanabe H, Shah JA, Sahara H, Shimizu A, Nomura S, Asfour A, Danton M, Boyd L, Dardenne Meyers A, Ekanayake-Alper DK, Sachs DH, Yamada K. Role of Intrinsic (Graft) Versus Extrinsic (Host) Factors in the Growth of Transplanted Organs Following Allogeneic and Xenogeneic Transplantation. Am J Transplant. 2017 Jan 24. doi: 10.1111/ajt.14210. [Epub ahead of print]
  • Kazuhiko Yamada, Jigesh A. Shah, Tatsu Tanabe, Miguel A. Lanaspa, Richard J. Johnso. Xenotransplantation: Where Are We with Potential Kidney Recipients? Recent Progress and Potential Future Clinical Trials. Current Transplantation Reports. 2017 June: 4 (2): 101-109. doi: 10.1007/s40472-017-0149-6
  • Jigesh A Shah, Tatsu Tanabe, Kazuhiko Yamada. Role of Intrinsic Factors in the Growth of Transplanted Organs Following Transplantation. J immuno Biol 2017, 2 (2): 122.1-14. doi: 10.4172/2476-1966.1000122
  • Kazuhiko Yamada, Masayuki Tasaki, Adam Griesemer and Jigesh Shah. Chapter 84: Xenotransplantation and Kidney Regenerative Technology: Kidney Transplantation, Bioengineering, and Regeneration 1st Edition -Kidney Transplantation in the Regenerative Medicine Era. Eds: Giuseppe Orlando, Giuseppe Remuzzi, David Williams. Publisher: AP – Elsevier.  eBook ISBN: 9780128018361, Hardcover ISBN: 9780128017340