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A New Tolerance Strategy for Diabetic Recipients

A novel approach involving transplantation of composite islet–kidney (IK) grafts in combination with tolerance induction could potentially become an attractive treatment option for diabetic patients with end-stage renal disease (ESRD) say researchers. CCTI principal investigator Kazuhiko Yamada and colleagues report that this strategy enabled graft acceptance and reduced the need for insulin therapy in a Rhesus macaque model. Click here for the full story on the Nature website. For Dr. Yamada's publication entitled "Tolerance of vascularized islet-kidney transplants in rhesus monkeys" on which the Nature Reviews highlight refers to, please click here.