Natural Killer Cells: An Anatomical View

Farber Lab Publishes in Latest Issue of Cell

Dr. Donna Farber's lab has published a study of the distribution and function of natural killer cells across various human tissues, revealing anatomic control of their development as well as populations that mediate immunosurveillance systemically.

 

Some Highlights
  • Highresolution map of human NK cells shows tissue-driven distribution across ages

  • Differentiated NK cells predominate in blood, bone marrow, spleen, and lungs

  • Tissueresident NK cells exhibit specific adaptations in mucosal and lymphoid sites

  • Lymph nodes and intestines are reservoirs for precursor and immature NK cells

The full paper, can be found here and an accompanying video produced by Cell here.