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Immunity publishes CCTI paper

Dendritic Cells Display Subset and Tissue-Specific Maturation Dynamics over Human Life

The latest issue of the journal Immunity features "Dendritic Cells Display Subset and Tissue-Specific Maturation Dynamics over Human Life" by Tomer Granot, et al of Dr. Donna Farber's lab. Some highlights include:

  • Human cDC1 and cDC2 subset distribution is a function of tissue site;
  • cDC2s exhibit maturation and migration phenotypes in mucosal-draining lymph nodes;
  • Mature cDC2s accumulate in lymph node interfollicular zones;
  • Localized cDC subset distribution and maturation is largely retained over life.

For the complete article, please go to the Immunity page here.