A Science Translational Medicine Paper
Studies of human immune diseases are generally limited to the analysis of peripheral blood lymphocytes of heterogeneous patient populations.
Columbia University Medical Center (CUMC) scientists have developed a way to recreate an individual's immune system in a mouse.
Dr. Megan Sykes featured in the Spring, 2011 edition of CUMC's P&S Magazine in "Reimagining Organ Transplantation", by Susan Conova.
Dr. Sykes discusses the CCTI's commitment to the strategy of preventing attacks on donated organs by the creation of a chimeric immune system within the transplant patient; one that is part donor...
Anette Wu, MD, PhD
Induction of Liver Allograft Tolerance through Bone Marrow Transplantation: Translational Preclinical Pilot Study in Monkeys
Nichole M. Danzl, PhD
Cell intrinisc immunopathology of type 1 diabetes in a humanized mouse model
Hiroyuki Tahara MD, PhD
There is a critical shortage of allogeneic organs. A more elegant, long-term solution is to use transplantation from other species. However, unresolved questions exist concerning the...