Daichi Shimbo, M.D.

  • Associate Professor of Medicine
  • Director, Laboratory, Center for Behavioral Cardiovascular Health
  • Director, Cardiovascular Physiology Research
Contact Information: 

622 W. 168th Street
PH 9 Room 310
New York, NY 10032
Phone: 212-342-4490
ds2231@cumc.columbia.edu

Google Scholar
Curriculum Vitae

Education

Board Certification:
Cardiovascular Medicine, Echocardiography
Fellowship:
Fellowship, Cardiovascular Medicine (2003), Mount Sinai School of Medicine
Chief Resident, Internal Medicine (1999), Mount Sinai School of Medicine
Residency:
Resident, Internal Medicine (1998), Mount Sinai School of Medicine, New York, NY
Graduate:
M.D., Medical School (1995), Albany Medical College, Albany, NY
Undergraduate:
B.S., Biomedical Engineering (1991), The Johns Hopkins University, Baltimore, MD

Research

Dr. Daichi Shimbo is the Director of the Laboratory at the Center for Behavioral Cardiovascular Health at Columbia University. He conducts translational research into the behavioral and biological mechanisms that underlie hypertension and cardiovascular disease. He has expertise in ambulatory blood pressure monitoring in the characterization of several blood pressure phenotypes based on diurnal pattern and office-ambulatory mismatch (white coat hypertension and masked hypertension). As a non-invasive cardiologist, Dr. Shimbo also has training in 2D and 3D-echocardiography for the assessment of cardiac structure and ventricular function. Presently, he is Principal Investigator of a Program Project study that examines the optimal strategies for the diagnosis of masked hypertension in the general population. This study investigates a range of stepped and non-stepped algorithms for diagnosing masked hypertension and to evaluate and compare their reproducibility and diagnostic accuracy. As the Director of Cardiovascular Physiology Research, Dr. Shimbo is the leader of the Core Laboratory for endothelium-dependent arterial vasodilation testing for several translational studies. He published one of the largest epidemiologic studies examining the relationship between impaired endothelium-dependent vasodilation and incident CVD events in a multi-ethnic population-based sample. In a second multi-ethnic population-based sample, he recently examined the relationship between impaired endothelium-dependent vasodilation and prevalent and incident hypertension. Recently, he was the Leader of the Core Lab for endothelium-dependent vasodilation testing for a multi-site NIH-sponsored study of pulmonary hypertension patients. Finally, he is the leader of the Core Lab for the assessment of endothelial microparticles (a marker of endothelial cell injury) for a multi-site NIH-sponsored study of chronic obstructive pulmonary disease patients. Dr. Shimbo has received numerous teaching awards, and has been an active mentor of several early career investigators.
 
Selected Publications

  1. Badimon JJ. Exaggerated serotonin-mediated platelet reactivity as a possible link in depression and the acute coronary syndromes. Am J Cardiol 2002; 89(3): 331-333
  2. Pickering TG, Shimbo D, Haas DC. Ambulatory Blood Pressure Monitoring. N Engl J Med 2006 Jun 1;354(22):2368-74
  3. Shimbo D, Kuruvilla S, Haas D, Pickering TG, Schwartz JE, Gerin W. Preventing misdiagnosis of ambulatory hypertension: algorithm using office and home blood pressures. J Hypertens. 2009 Sep;27(9):1775-83.
  4. Shimbo D, Muntner P, Mann D, Viera A, Homma S, Polak JF, Herrington D, Shea S. Endothelial Dysfunction and the Risk of Hypertension: The Multi-Ethnic Study of Atherosclerosis. Hypertension. 2010 Jun;55(6):1339-45.
  5. Newman JD, Davidson KW, Shaffer JA, Schwartz JE, Chaplin W, Kirkland S, Shimbo D. Observed Hostility and the Risk of Incident Ischemic Heart Disease: A Prospective Population Study from the 1995 Canadian Nova Scotia Health Survey. J Am Coll Cardiol. 2011 Sep 13;58(12):1222-8.
  6. Kawut SM, Bagiella E, Lederer DJ, Shimbo D, Horn EM, Roberts KE, Hill NS, Barr RG, Rosenzweig EB, Post W, Tracy RP, Palevsky HI, Hassoun PM, Girgis RE; ASA-STAT Study Group.
  7. Randomized clinical trial of aspirin and simvastatin for pulmonary arterial hypertension: ASA-STAT. Circulation. 2011 Jun 28;123(25):2985-93.